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Korsakoff's syndrome on the MMPI-2

Published online by Cambridge University Press:  24 June 2014

Jos I. M. Egger ,
Arie J. Wester ,
Hubert R. A. De Mey  and
Jan J. L. Derksen
Jos I. M. Egger*
Affiliation:
University of Nijmegen, Nijmegen, the Netherlands Vincent van Gogh Institute for Psychiatry, Venray, the Netherlands
Arie J. Wester
Affiliation:
Vincent van Gogh Institute for Psychiatry, Venray, the Netherlands
Hubert R. A. De Mey
Affiliation:
University of Nijmegen, Nijmegen, the Netherlands
Jan J. L. Derksen
Affiliation:
University of Nijmegen, Nijmegen, the Netherlands
*
Jos I.M. Egger, Department of Clinical Psychology and Personality, University of Nijmegen, PO Box 9104, 6500 HE Nijmegen, the Netherlands. Tel: + 31 (0) 24 3612668; Fax: + 31 (0) 478 630797; E-mail: jegger@baserv.uci.kun.nl
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Abstract

Background:

This article describes an exploratory study of MMPI-2 administration to 20 patients with Korsakoff's disease, all admitted to the Korsakoff unit of a major psychiatric hospital in the Netherlands.

Methods:

We compared their MMPI-2 basic profiles with those of an inpatient alcohol-dependent non-Korsakoff group. Attention was also given to content scales and some selected supplementary scales. Furthermore, we explored the differences between MMPI-2 profiles of Korsakoff patients with and without insight into oneself and one's disease.

Results:

Compared with both the Dutch norms and the scale means of the non-Korsakoff alcoholics, Korsakoff patients showed an extraordinary flat profile. Illness insight appeared to be related to the levels of the various scales.

Discussion:

The results show the potential usefulness of the MMPI-2 in the differential diagnosis of chronic alcoholism and Korsakoff's disease.

Keywords

chronic alcoholismKorsakoffMMPI-2neuropsychiatric disorderspsychological assessmentpsychological profile
Type
Original Article
Information
Acta Neuropsychiatrica , Volume 14 , Issue 5 , October 2002 , pp. 231 - 236
Copyright
Copyright © Acta Neuropsychiatrica 2002

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References

Korsakow, SS. Psychosis polyneuritica sum cerebropathia psychica toxaemica. Medizinskoje Obozrenije 1889: 31. Google Scholar
Kopelman, MD. The Korsakoff syndrome. Br J Psychiatry 1995;166: 154–173.CrossRefGoogle ScholarPubMed
Plutchik, R, Discipio, WJ. Personality patterns in chronic alcoholism (Korsakoff's syndrome), chronic schizophrenia, and geriatric patients with chronic brain syndrome. J Am Geriatr Soc 1974;22: 514–516.CrossRefGoogle Scholar
Plomin, R, McClearn, GE, eds. Nature, Nurture and Psychology. Washington DC: American Psychological Association, 1993. CrossRefGoogle Scholar
Kirkpatrick, BRyan, WG. At issue: a default analysis for schizophrenia research. Schizophr Bull 2000;26: 157–161.CrossRefGoogle ScholarPubMed
Ben-Porath, YSButcher, JNGraham, JR. Contribution of the MMPI-2 content scales to the differential diagnosis of schizophrenia and major depression. Psychol Assessm 1991;3: 634–640. CrossRefGoogle Scholar
Delisi, LE. A new classification for the psychoses? Arch General Psychiatry 1999;56: 672. CrossRefGoogle ScholarPubMed
Butters, N. Alcoholic Korsakoff's syndrome: Some unresolved issues concerning etiology, neuropathology, and cognitive deficits. J Clin Exp Neuropsychol 1985;7: 181–210.CrossRefGoogle Scholar
APA. Diagnostic and Statistical Manual of Mental Disorders, 4th edn. Washington DC: American Psychiatric Association, 1994. Google ScholarPubMed
Eyskens, E, Feenstra, L, Meinders, AE, Vandenbroucke, JP. Codex Medicus, 9th edn. Arnhem: Elsevier, 1991. Google Scholar
NIGZ. Alcohol en de Hersenen [Alcohol and the Brain]. Worden: Dutch Institute for Health Prevention (NIGZ), 1999. Google Scholar
Victor, M, Adams, RD, Collins, GH. The Wernicke–Korsakoff Syndrome and Related Neurological Disorders due to Alcoholism and Malnutrition. Philadelphia: F.A. Davis, 1989. Google Scholar
Blansjaar, BA, Vielvoye, GJ, Van Dijk, JG, Rijnders, RJ. Similar brain lesions in alcoholics and Korsakoff patients: MRI, psychometric and clinical findings. Clin Neurol Neurosurg 1992;94: 197–203.CrossRefGoogle ScholarPubMed
Blansjaar, BA. Het syndroom van Korsakoff [Korsakoff's syndrome]. Ndl Tijdschr Geneeskd 1993;137: 1043–1048. Google Scholar
Ganzevles, PG J, De Geus, BW J, Wester, AJ. Cognitive and behavioral aspects of Korsakoff's syndrome: the effect of special Korsakoff wards in a general psychiatric hospital. Tijdschr Alcohol Drugs Andere Psychotrope Stoffen 1994;20: 20–31. Google Scholar
Blansjaar, BA, Takens, H, Zwinderman, Ah. The course of alcohol amnestic disorder: a three-year follow-up study of clinical signs and social disabilities. Acta Psychiatr Scand 1992;86: 240–246.CrossRefGoogle ScholarPubMed
NZI. Statistics on Psychiatric Hospitals in the Netherlands. Utrecht, Nederlands: Ziekenhuis Instituut, 1992. Google ScholarPubMed
Butcher, JN, Dahlstrom, WG, Graham, JR, Tellegen, A, Kaemmer, B. Minnesota Multiphasic Personality Inventory (MMPI-2): Manual for Adminstration and Scoring. Minneapolis: University of Minnesota Press, 1989. Google Scholar
Derksen, JJ L, De Mey, HR A, Sloore, H, Hellenbosch, G. MMPI-2: Handleiding Bij Afname, Scoring En Interpretatie, 3rd edn. Nijmegen: PEN Test Publisher 1997. Google Scholar
Johnson, RS, Tobin, JW, Cellucci, T. Personality characteristics of cocaine and alcohol abusers: more alike than different. Addictive Behav 1992;17: 159–166. CrossRefGoogle ScholarPubMed
Nace, EP, Davis, CW, Gaspari, JP. Axis II comorbidity in substance abusers. Am J Psychiatry 1991;148: 118–120.Google Scholar
Butcher, JN, Williams, CL. Essentials of MMPI-2 and MMPI-A Interpretation. Minneapolis: University of Minnesota Press 1998. Google Scholar
Alfano, DP, Finlayson, MA, Stearns, GM, Neilson, PM. The MMPI and neurologic dysfunction. profile configuration and analysis. Clin Neuropsychol 1990;4: 69–79. CrossRefGoogle Scholar
Cripe, LI, Dodrill, CB. Neuropsychological test performances with chronic low-level formaldehyde exposure. Clin Neuropsychol 1988;2: 41–48. CrossRefGoogle Scholar
De Mey, HR A, Derksen, JJ L. The new ‘uniform’ of the MMPI-2: about T-scores. Gedrag Gezondheid 1995;23: 179–184. Google Scholar
MacAndrew, C. The differentiation of male alcoholic outpatients from nonalcoholic inpatients by means of the MMPI. Quart J Studies Alcohol 1965;26: 43–51. Google Scholar
Preng, KW, Clopton, JR. The MacAndrew Scale: clinical application and theoretical issues. J Studies Alcohol 1986;47: 228–236. CrossRefGoogle ScholarPubMed
Preng, KW, Clopton, JR. Application to the MacAndrew Alcoholism Scale to alcoholics with psychiatric diagnoses. J Personal Assessm 1986;50: 113–122. CrossRefGoogle ScholarPubMed
Weed, NC, Butcher, JN, McKenna, T, Ben Porath, YS. New measures for assessing alcohol and drug abuse with the MMPI-2. The APS and AAS. J Personal Assessm 1992;58: 389–404. CrossRefGoogle Scholar
Greene, RL, Weed, NC, Butcher, JN, Arredondo, R, Davis, HG. A cross-validation of MMPI-2 substance abuse scales. J Personal Assessm 1992;58: 405–410. CrossRefGoogle ScholarPubMed
Theuns, P, De Mey, HR A, Schaeks, HM J, Bögels, T, Roverts, A, Derksen, JJ L. MMPI-2. Computer Program for Administration and Scoring. Nijmegen: PEN Test Publisher 1994. Google Scholar
Marks, PA, Seeman, W. An Atlas for Use with the MMPI. Actuarial Description of Abnormal Personality. Baltimore: Williams & Wilkins, 1963. Google Scholar
Schippers, GM, Lammers, SM M, Schaap, CPDR, eds. Contributions to the Psychology of Addiction. Lisse: Swets and Zeitlinger, 1991. Google Scholar
Graham, JR, Ben-Porath, YS, McNulty, JL. MMPI-2 Correlates for Outpatient Community Mental Health Settings. Minneapolis: University of Minnesota Press 1999. Google Scholar
Graham, JR. MMPI-2. Assessing Personality and Psychopathology, 2nd edn. New York: Oxford University Press 1993. Google Scholar
Cummings, JL. Frontal-subcortical circuits and human behavior. Arch Neurol 1993;50: 873–880.CrossRefGoogle ScholarPubMed
Cummings, JL. Principles of neuropsychiatry: towards a neuropsychiatric epistemology. Neurocase 1999;5: 181–188. CrossRefGoogle Scholar