Hostname: page-component-78c5997874-94fs2 Total loading time: 0 Render date: 2024-11-13T02:43:56.041Z Has data issue: false hasContentIssue false

Leeftijdsgeassocieerde cognitieve functiestoornissen: Cognitive aging in a longitudinal perspective: the Maastricht Aging Study (MAAS)

Published online by Cambridge University Press:  18 September 2015

J. Jolles*
Affiliation:
Vakgroep Psychiatrie en Neuropsychologie, Universiteit Maastricht
M.P.J. van Boxtel
Affiliation:
Vakgroep Psychiatrie en Neuropsychologie, Universiteit Maastricht
R.W.H.M. Ponds
Affiliation:
Vakgroep Psychiatrie en Neuropsychologie, Universiteit Maastricht
J.F.M. Metsemakers
Affiliation:
Vakgroep Huisartsgeneeskunde, Universiteit Maastricht
P.J. Houx
Affiliation:
Vakgroep Psychiatrie en Neuropsychologie, Universiteit Maastricht
*
Instituut Hersenen & Gedrag, Universiteit Maastricht, Vakgroep Psychiatrie en Neuropsychologic Postbus 616, 6200 MD Maastricht

Summary

Cognitive dysfunctions in old individuals can be a precursor of dementia. The Maastricht Aging Study (MAAS) was designed to characterize the usual and pathological aging of cognitive function. The study involves a group of 1,900 initially healthy individuals who will be followed-upfor a period of 12 years with respect to health characteristics and neurocognitive status. For this purpose a sample was drawn from a patient register of collaborating family practices, stratified for age (range 24 to 81 years), sex and general ability level. Rationale and design of MAAS are discussed and also some findings from the cross-sectional baseline measurement: general aspects of memory and attention, cognitive functioning after brain trauma and general anesthesia, physical condition (fitness, morbidity and vascular risk factors) as predictor of cognitive function, and finally cognitive complaints and metamemory.

Type
Research Article
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Literatuur

1. Jolles, J. Cognitive, emotional and behavioral dysfunctions in aging and dementia. In: Swaab, DF, Fliers, E, Mirmirian, M, van Gool, WA, van Haaren, F, eds. Progress in Brain Research. Amsterdam: Elsevier Sci Publ, 1986: 70, 1539.Google Scholar
2. Rabbitt, P. Applied cognitive gerontology: Some problems, methodology and data. Appl Cogn Psychol 1990; 4: 143–9.10.1002/acp.2350040402Google Scholar
3. Jolles, J, Houx, PJ, van Boxtel, MPJ, Ponds, RWHM, eds. Maastricht Aging Study: Determinants of cognitive aging. Maastricht: Neuropsych Publish, 1995.Google Scholar
4. Houx, PJ, Vreeling, FW, Jolles, J. Rigorous health screening reduces age effect on memory scanning task. Brain Cogn 1991; 15: 246–60.10.1016/0278-2626(91)90029-8Google Scholar
5. Houx, PJ, Jolies, J. Age-related decline of psychomotor speed: Effects of age, brain health, sex, and education. Percep Mot Skills 1993; 76: 195211.10.2466/pms.1993.76.1.195Google Scholar
6. Jolies, J, Verhey, FRJ, Riedel, WJ, Houx, PJ. Cognitive impaiment in elderly people: Predisposing factors and implications for experimental drug studies. Drugs Aging 1995; 7:459–79.Google Scholar
7. Jolies, J, van Boxtel, MPJ, Ponds, RWHM, Metsemakers, JFM, Houx, PJ. De Maastricht Aging Study (MAAS): Het longitudinaal perspectief van cognitieve veroudering. Tijdschr Geront Geriat 1998; 29: 120–9.Google Scholar
8. Klein, M, Houx, PJ, Jolies, J. Long-term persisting cognitive sequelae of closed head injury and the effect of age. J Nerv Ment Dis 1996; 184: 459–67.10.1097/00005053-199608000-00002Google Scholar
9. Møller, JT, Cluitmans, P, Rasmussen, L, et al. Long-term postoperative dysfunction in the elderly: ISPOCD-1 Study. Lancet 1998; 351: 857–61.10.1016/S0140-6736(97)07382-0Google Scholar
10. Van Boxtel, MPJ, Buntinx, F, Houx, PJ, Metsemakers, JFM, Knottnerus, JA, Jolies, J. Prevalent morbidity as recorded by the general practitioner and cognitive performance in a normal aging population. J Geront-Med Sci 1998; 53A: M146–54.Google Scholar
11. Van Boxtel, MPJ, Gaillard, C, Houx, PJ, Buntinx, F, de Leeuw, PW, Jolies, J. Can the blood pressure predict cognitive task performance in a healthy population sample. J Hypert 1997; 15: 1069–79.10.1097/00004872-199715100-00004Google Scholar
12. Ponds, RWHM, Commissaris, CJAM, Jolies, J. Prevalence and covariates of subjective forgetfulness in a normal population. In J Aging Hum Develop 1997; 45: 207–21.10.2190/MVQ1-WB58-875H-Y4X0CrossRefGoogle Scholar