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Neuropathological studies of bipolar disorder

Published online by Cambridge University Press:  18 September 2015

P.J. Harrison
P.J. Harrison*
Affiliation:
University Department of Psychiatry, Oxford, United Kingdom
*
Neurosciences Building, University Department of Psychiatry, Warneford Hospital, Oxford 0X3 7JX, United Kingdom Fax 00-44-1865 251076, E-mail paul.harrison@psych.ox.ac.uk
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Abstract

The few available neuropathological studies of bipolar disorder are reviewed and placed in the context of structural imaging findings. Candidate pathological processes include cy-toarchitectural abnormalities, particularly in the anterior cingulate cortex and affecting glia, and disruption of white matter connections. The possible neuropathological relationship of bipolar disorder with major depression and with schizophrenia is discussed.

Keywords

astrocytesaffective disordermood disorderneuropathologypost mortem
Type
Articles
Information
Acta Neuropsychiatrica , Volume 12 , Issue 3 , September 2000 , pp. 96 - 98
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 2000

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