Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-13T03:20:12.711Z Has data issue: false hasContentIssue false

Self-injurious behavior and mental retardation; a multidisciplinary approach

Published online by Cambridge University Press:  18 September 2015

W.M.A. Verhoeven*
Affiliation:
Vincent van Gogh Instituut, Venray
A. Dosen
Affiliation:
Nieuw Spraeland, Oostrum-Venray
S. Tuinier
Affiliation:
Vincent van Gogh Instituut, Venray
A.E.S. Sijben
Affiliation:
Vincent van Gogh Instituut, Venray
*
Vincent van Gogh Instituut voor Psychiatrie, Stationsweg 46, 5803 AC Venray

Summary

Research on the phenomenon of self-injurious behaviour (SIB) has been very limited despite the relative high prevalence of this type of disorder. The relative lack of knowledge of psychopathology in this field and the methodological problems in performing research projects may have contributed to the limitations in the interest for this area. Recently, research into biological aspects of the etiopathogenesis of SIB has yielded results that might open new vistas for a rational and effective pharmacotherapeutical approach. In this concise review the psychiatric, neurological, biological, pharmacological and methodological aspects of SIB in mental retardation will be mentioned.

Type
Research Article
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Literatuur

1.Winchel, RM, Stanley, M. Self-injurious behavior: a review of the behavior and biology of self-mutilation. Am J Psychiat 1991; 148:306–15.Google ScholarPubMed
2.Rojahn, J. Self-injurious and stereotypic behavior of noninstitutionalized mentally retarded people: prevalence and classification. Am J ment Defic 1986; 91:268–76.Google ScholarPubMed
3.Reis, S. Prevalence of dual diagnosis in community-based day programs in the Chicago metropolitan area. Am J ment Retard 1990; 4:578–85.Google Scholar
4.Duker, PCC. Zelfverwondend gedrag bij zwakzinnigen: ge-dragsanalyse en -therapie. Nijmegen: KUN, 1975: Proefschrift.Google Scholar
5.Oliver, C, Murphy, GH, Corbett, JA. Self-injurious behavior in people with mental handicap: a total population study. J ment Defic Res 1978; 31:147–62.Google Scholar
6.Campbell, M, Malone, RP. Mental retardation and psychiatric disorders. Hosp Comm Psychiat 1991; 42:374–79.Google ScholarPubMed
7.Gualtieri, CT. The differential diagnosis of self-injurious behavior in mentally retarded people. Psychopharmacol Bull 1989; 25:358–63.Google ScholarPubMed
8.Menolascino, FJ. Mental illness in the mentally retarded: diagnostic issues and treatment considerations. In: Dosen, A, Van Gennep, A en Zwanikken, GJ, red. Treatment of Mental Illness and behavioral Disorder in the Mentally Retarded. Leiden: Logon Publications, 1990; 2136.Google Scholar
9.Dosen, A. Psychische stoornissen bij zwakzinnige kinderen. Lisse: Swets en Zeitlinger, 1983: Proefschrift.Google Scholar
10.Zwanikken, GJ, Fischer, AA, Zitman, FG, red. Psychiatrie, Utrecht: Bunge, 1990.Google Scholar
11.Verhoeven, WMA, Tuinier, S, Sijben, AES. Biological and pharmacological aspects of selfinjurious behaviour. In: Fletcher, RJ, red. Mental Health Aspects of Mental Retardation. New York: Lexington Books, in press.Google Scholar
12.Kars, H, Broekema, W, Glaudemans-van Gelderen, I, Verhoeven, WMA, Van Ree, JM. Naltrexone attenuates self-injurious behavior in mentally retarded subjects. Biol Psychiat 1990; 27:741–6.CrossRefGoogle ScholarPubMed
13.Sijben, AES. Omzien naar Weldoen, Programma Evaluatie in Theorie en Praktijk. Nijmegen: K.U., 1986: Proefschrift.Google Scholar
14.Dosen, A. Agressief en zichzelf beschadigend gedrag bij zwakzinnigen. In: Dosen, A, red. Psychische en Gedragsstoornissen bij Zwakzinnigen; een ontwikkelingsdynamische Benadering. Amsterdam: Boom Meppel 1990: 251–60.Google Scholar
15.Dosen, A. Diagnostic and treatment of mental illness in mentally retarded children; a developmental model. Child Psychiat hum Devel 1989; 20:7384.CrossRefGoogle ScholarPubMed
16.Bueno, M. Mental deficiency. Concept, epidemiology and preventive measures. In: Seva, A, red. European Handbook of Psychiatry and Mental Health. Barcelona: Anthropos 1991: 1507–22.Google Scholar
17.Lesch, M, Nyhan, WL. A familial disorder of uric acid metabolism and central nervous system function. Am J Med 1964; 36:561–70.CrossRefGoogle ScholarPubMed
18.Lloyd, KG, Hornykiewicz, O, Davidson, L, Shannak, K, Farley, I, Goldstein, M, Shibuya, M, Kelley, WN, Fox, IH. Biochemical evidence of dysfunction of brain neurotransmitters in the Lesch-Nyhan syndrome. N Engl J Med 1981; 305:1106–11.CrossRefGoogle ScholarPubMed
19.Breese, GR, Criswell, HE, Duncan, GE, Mueller, RA. Dopamine deficiency in self-injurious behavior. Psychopharmacol Bull 1989; 25:353–7.Google ScholarPubMed
20.Verhoeven, WMA, Tuinier, S. Pharmacotherapy in aggressive and autoaggressive behaviour. In: Dosen, A en Day, K, red. The Treatment of Mental Illness and Behaviour Disorders in mentally retarded Children and Adults. London: Royal College of Psychiatrists, in press.Google Scholar
21.Tuinier, S. De Psychiater en de Wilde Man; een Veldstudie over de Relatie psychiatrisch Syndroom en Criminaliteit. Proefschrift Meppel: Drukkerij Giethoorn, 1989.Google Scholar
22.Greenberg, AS, Coleman, M. Depressed 5-hydoxyindole levels associated with hyperactive and aggressive behavior. Relationship to drug response. Arch gen Psychiat 1976; 33:331–6.CrossRefGoogle Scholar
23.O'Neal, M, Page, N, Atkins, WN, Eichelmann, B. Tryptophan-trazadone treatment of aggressive behavior. Lancet 1986; 2:859–60.CrossRefGoogle Scholar
24.Gillberg, C, Terenius, L, Lunnerholm, G. Endorphin activity in childhood psychosis. Arch gen Psychiat 1985; 42:780–3.CrossRefGoogle ScholarPubMed
25.Sandman, CA, Barron, JL, Chicz-Demet, A, Demet, EM. Plasma Bendorphin levels in patients with self-injurious behavior and stereotypy. Am J ment Retard 1990; 95:8492.Google ScholarPubMed
26.Rasmussen, DL, Olivier, B, Raghoebar, M, Mos, J. Possible clinical applications of serenics and some implications of their preclinical profile for their clinical use in psychiatric disorders. In: Raghoebar, M, Olivier, B, Rasmussen, DL, Mos, J, red. Drug Metabolism and Drug Interactions, Eltoprazine: a serenic compound. London: Freund Publ House, 1989: 159–86.Google Scholar
27.Zwanikken, GJ, Sijben, AES. Psychiaters en zwakzinnigenzorg. Tijdsch Psychiat 1991; 533:530–40.Google Scholar