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Familial risks and genetic counselling for common psychiatric disorders

Published online by Cambridge University Press:  02 January 2018

Jane Scourfield  and
Peter McGuffin
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The main aim of genetic counselling is to inform about disorders that may have a genetic basis. The following definition is a helpful starting point:

Type
Research Article
Information
Advances in Psychiatric Treatment , Volume 5 , Issue 1 , January 1999 , pp. 39 - 45
Copyright
Copyright © The Royal College of Psychiatrists 1999 

References

American College of Medical Genetics/American Society of Human Genetics Working Group on ApoE and Alzheimer Disease (1995) Statement on the use of apolipoprotein E testing for Alzheimer's disease. Journal of the American Medical Association, 274, 1627–1629.CrossRefGoogle Scholar
American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM–IV) Washington, DC: APA.Google Scholar
Bertelsen, A., Harvald, B. & Hauge, M. (1977) A Danish twin study of manic depressive disorders. British Journal of Psychiatry, 130, 330–351.CrossRefGoogle ScholarPubMed
Bohman, M., Sigvardsson, S. & Cloninger, C. R. (1981) Maternal inheritance of alcohol abuse: cross-fostering analysis of adopted women. Archives of General Psychiatry, 35, 965–969.CrossRefGoogle Scholar
Cardno, A., Murphy, K. & McGuffin, P. (1997) The genetics of schizophrenia. In Basic and Clinical Science of Mental and Addictive Disorders (eds Judd, L., Saletu, B. & Filip, V.) pp. 89–104. Basel: Karger.CrossRefGoogle Scholar
Clarke, A. (1994) Genetic Counselling: Practice and Principles. London: Routledge.CrossRefGoogle Scholar
Cloninger, C., Bohman, M. & Sigvardsson, S. (1981) Inheritance of alcohol abuse: cross-fostering analysis of adopted men. Archives of General Psychiatry, 38, 861–868.CrossRefGoogle ScholarPubMed
Crocq, M. A., Mant, R., Asherson, P. et al (1992) Association between schizophrenia and homozygosity at the dopamine D3 receptor gene. Journal of Medical Genetics, 29, 858–860.CrossRefGoogle ScholarPubMed
Gottesman, I. I. (1991) Schizophrenia Genesis. New York: W. H. Freeman Google Scholar
Gottesman, I. I. & Shields, J. (1982) Schizophrenia, the Epigenetic Puzzle. Cambridge: Cambridge University Press.Google Scholar
Gurling, H., Murray, R. & Clifford, C. A. (1981) Investigations into the genetics of alcohol dependence and into its effect on brain function. In Twin Research 3, Part C. Epidemiological and Clinical Studies (eds Gedda, L., Parisi, P. & Nance, W.) pp. 77–87. New York: Alan R. Liss.Google Scholar
Harper, P. (1993) Practical Genetic Counselling. London: Butterworth.Google Scholar
Harper, P., Soldan, J. & Tyler, A. (1996) Predictive tests in Huntington's disease. In Huntington's Disease (ed. Harper, P.) pp. 395–425. London: W. B. Saunders Google ScholarPubMed
Heath, A. C., Bucholz, K. K., Madden, P. A. F. et al (1997) Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men. Psychological Medicine, 27, 1381–1396.CrossRefGoogle Scholar
Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell, 72, 971–983.CrossRefGoogle Scholar
McGuffin, P. & Katz, R. (1986) Nature, nurture and affective disorder. In The Biology of Depression (ed. Deakin, J.) pp. 26–52. London: Gaskell.Google Scholar
McGuffin, P., Asherson, P., Owen, M. et al (1994a) The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia? British Journal of Psychiatry, 164, 593–599.CrossRefGoogle ScholarPubMed
McGuffin, P., Owen, M. J., O'Donovan, M. C. et al (1994b) Seminars in Psychiatric Genetics. London: Gaskell.Google Scholar
McGuffin, P., Katz, R., Watkins, S. et al (1996) A hospital-based twin register of the heritability of DSM–IV unipolar depression. Archives of General Psychiatry, 53, 129–136.CrossRefGoogle ScholarPubMed
Murphy, E. A. & Chase, G. A. (1975) Principles of Genetic Counselling. Chicago, IL: Yearbook Publishers.Google Scholar
Murphy, K., Cardno, A. & McGuffin, P. (1996) The molecular genetics of schizophrenias. Journal of Molecular Neuroscience, 7, 147–157.CrossRefGoogle Scholar
Pickens, R., Svikis, D. & McGue, M. (1991) Heterogeneity in the inheritance of alcoholism. Archives of General Psychiatry, 48, 19–28.CrossRefGoogle ScholarPubMed
Quaid, K. (1993) Presymptomatic testing for Huntington's disease in the United States. American Journal of Human Genetics, 53, 785–787.Google ScholarPubMed
Reich, T. & Cloninger, R. (1990) Time-dependent model of the familial transmission of alcoholism. In Genetics and Biology of Alcoholism. Banbury Report 33, pp. 55–73. Cold Spring Harbor: Cold Spring Harbor Press.Google Scholar
Tsuang, M. T. (1978) Genetic counseling for psychiatric patients and their families. American Journal of Psychiatry, 135, 1465–1475.Google ScholarPubMed
Williams, J., McGuffin, P., Nothen, M. et al (1997) A meta-analysis of association between the 5-HT2a receptor T102C polymorphism and schizophrenia. Lancet, 349, 1221.CrossRefGoogle ScholarPubMed
World Federation of Neurology Research Committee. Research Group on Huntington's Disease (1989) Ethical issues policy statement on Huntington's disease molecular genetics predictive test. Journal of Neurological Science, 94, 327–332.CrossRefGoogle Scholar
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