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Application of XRF to Measure Strontium in Human Bone In Vivo

Published online by Cambridge University Press:  06 March 2019

L. Wielopolski ,
D. Vartsky ,
S. Yasumura  and
S.H. Cohn
L. Wielopolski
Affiliation:
Brookhaven National Laboratory, Medical Research Center, Upton, New York 11973
D. Vartsky
Affiliation:
Brookhaven National Laboratory, Medical Research Center, Upton, New York 11973
S. Yasumura
Affiliation:
Brookhaven National Laboratory, Medical Research Center, Upton, New York 11973
S.H. Cohn
Affiliation:
Brookhaven National Laboratory, Medical Research Center, Upton, New York 11973
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Extract

Strontium appears in the earth's crust at a concentration of about 400 ppm and in sea water about 8,1 ppm. Consequently, all living forms have evolved in the presence of this alkaline earth and have incorporated it in their tissues. The exact role of Sr in the human body remains ambiguous (1), even though Sr has been extensively studied with reference to the radiation hazard from 90Sr (2).

Metabolic behavior of Sr, in some aspects, is similar to that of Ca (3), but substantial dissimilarities between these two are also well recognized (1,4). It has been suggested that Sr stimulates the formation of bone matrix. At higher concentrations, however, it interferes with calcification mechanism of the bone matrix (5).

Type
VIII. XRF General Applications
Information
Advances in X-Ray Analysis , Volume 26: Thirty-First Annual Conference on Applications of X-ray Analysis, August 1-6, 1982 , 1982 , pp. 415 - 421
Copyright
Copyright © International Centre for Diffraction Data 1982

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References

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