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Cardiovascular Reflexes in Monozygotic Twins Discordant for Exposure to Organic Solvents

Published online by Cambridge University Press:  01 August 2014

E. Matikainen ,
J. Juntunen ,
M. Koskenvuo ,
M. Antti-Poika  and
J. Kaprio
E. Matikainen*
Affiliation:
Institute of Occupation Health, Helsinki, Finland
J. Juntunen
Affiliation:
Institute of Occupation Health, Helsinki, Finland
M. Koskenvuo
Affiliation:
Department of Public Health, University of Helsinki, Finland
M. Antti-Poika
Affiliation:
Institute of Occupation Health, Helsinki, Finland
J. Kaprio
Affiliation:
Department of Public Health, University of Helsinki, Finland
*
Institute of Occupational Health, Topeliuksenkatu 41 a A, SF-00250 Helsinki, Finland

Abstract

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Eighteen pairs of monozygotic twins discordant for long-term occupational exposure to organic solvents were examined for disturbances of cardiovascular reflexes. All of the subjects were asymptomatic, and considered themselves healthy. No significant differences were observed between the exposed and the nonexposed twins. The finding suggests that occupational solvent exposure at these particular levels is unlikely to cause disturbances of the autonomic nervous function.

Keywords

NeuropathySolvent exposureCotwin control study
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 36 , Issue 4 , October 1987 , pp. 503 - 507
Copyright
Copyright © The International Society for Twin Studies 1987

References

REFERENCES

1. Allen, N (1979): Solvents and other industrial organic compounds. In Vinken, PJ, Bruyn, GW (eds): Intoxications of Nervous System, Part I. Amsterdam: North-Holland, pp 361–389.Google Scholar
2. Endré, ZH, Perl, SI, Kraegen, EW, Chasleworth, JA, McDonald, GJ (1981): Reduced cardiac beat-to-beat variation in chronic renal failure: a ubiquitous marker of autonomic neuropathy. Clin Sci 5:561–563.Google Scholar
3. Edwing, DJ, Borsey, DQ, Bellavere, G, Clarke, BF (1981): Cardiac autonomic neuropathy in diabetes: comparison of measures of R-R interval variation. Diabetologia 21:18–24.CrossRefGoogle Scholar
4. Juntunen, J (1986): Occupational solvent poisoning: clinical aspeets. In Riihimäki, V, Ulfvarsson, U, (eds): Safety and Health Aspeets of Organic Solvents. New York: Alan R Liss, pp 265–279.Google Scholar
5. Juntunen, J, Hupli, V, Hernberg, S, Luisto, M (1976): Neurological picture of organic solvent poisoning in industry. Int Arch Occup Environ Health 2:14–20 Google Scholar
6. Juntunen, J, Matikainen, E, Antti-Poika, M, Suoranta, H, Valle, M (1985): Nervous system effects of long-term occupational exposure to toluene. Acta Neurol Scand 72:512–517.CrossRefGoogle ScholarPubMed
7. Levin, AB (1966): A simple test of cardiac function based upon the heart rate changes induced by the Valsalva manoeuvre. Am J Cardiol 18:90–99.CrossRefGoogle Scholar
8. Matikainen, E (1982): Diabetic Neuropathy: A Clinical, Electrophysiological and Histopathological Study. Academic dissertation, University of Helsinki, pp 1–111.Google Scholar
9. Matikainen, E, Juntunen, J (1985): Autonomic nervous system dysetion in workers exposed to organic solvents. J Neuiol Neurosurg Psychiatry 48:1021–1024.CrossRefGoogle ScholarPubMed
10. Matikainen, E, Juntunen, J, Salmi, T (1986): Autonomic dysfunction in long-standing alcoholism. Alcohol & Alcoholism 21:69–73.Google ScholarPubMed
11. McLeod, JG (1980): Autonomic nervous system. In Sumner, AJ (ed): The Physiology of Peripheral Nerve Disease. Philadelphia: WB Saunders Co.Google Scholar
12. Sundkvist, G, Almér, LO, Lilja, B (1979): Respiratory influence on heart rate in diabetes mellitus. Br Med J 1:924–926.CrossRefGoogle ScholarPubMed