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Cleft lip and palate in thalidomide-induced embryopathies*
Published online by Cambridge University Press: 01 August 2014
Summary
In 3 out of 161 cases of thalidomide embryopathy seen in Hamburg, typical malformations of thalidomide causation were associated with cleft lip and/or palate. The same association was present in 6 out of 918 cases of thalidomide embryopathy reported by correspondence. Clefts of the face are more common in thalidomide children than in other children. Usually, they are associated with ear deformities. In cases of aplasia of the radius observed before the introduction of thalidomide but not in those connected with thalidomide intake, clefts are more common than in the general population. The association of clefts and ear deformities has been known before the introduction of thalidomide. Thalidomide is probably the cause of only some cases of association.
- Type
- Research Article
- Information
- Acta geneticae medicae et gemellologiae: twin research , Volume 16 , Issue 3 , July 1967 , pp. 244 - 274
- Copyright
- Copyright © The International Society for Twin Studies 1967
Footnotes
Diese Arbeit wurde der Medizinischen Fakultät der Universität Hamburg als Dissertation zur Erlangung des Grades eines Doktors der Medizin vorgelegt.
References
Literaturverzeichnis
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