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Estimates of Genetic and Environmental Components of Serum Isocitrate Dehydrogenase (ICDH) in Normal Twins

Published online by Cambridge University Press:  01 August 2014

D. Rapaport ,
G.M.D.D. Colletto ,
M. Vainzof  and
M. Zatz
D. Rapaport
Affiliation:
Department of Biology, Bioscience Institute, University of Sao Paulo, Brazil
G.M.D.D. Colletto
Affiliation:
Informatics and Data Analysis Division, Biomedical Science Institute, University of Sao Paulo, Brazil
M. Vainzof
Affiliation:
Department of Biology, Bioscience Institute, University of Sao Paulo, Brazil
M. Zatz*
Affiliation:
Department of Biology, Bioscience Institute, University of Sao Paulo, Brazil
*
Departamento de Biologia, Universidade de São Paulo, Caixa Postal 11461, São Paulo, SP, Brazil

Abstract

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Environmental (b2) and genetic heritability (h2) of serum isocitrate dehydrogenase (ICDH) were estimated in 96 pairs of healthy twins according to a path analysis model. The results showed significant heritability (0.42) and a very low environmental component (based on obesity and level of habitual physical activity), suggesting that these factors do not influence ICDH serum activity.

Keywords

Isocitrate dehydrogenaseObesityHeritabilityTwins
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 40 , Issue 1 , January 1991 , pp. 77 - 82
Copyright
Copyright © The International Society for Twin Studies 1991

References

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