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Excessive Follicular Recruitment and Growth in Mothers of Spontaneous Dizygotic Twins

Published online by Cambridge University Press:  01 August 2014

N.G. Martin ,
S. Shanley ,
K. Butt ,
J. Osborne  and
G. O'Brien
N.G. Martin*
Affiliation:
Queensland Institute of Medical Research, Brisbane, Australia
S. Shanley
Affiliation:
Queensland Institute of Medical Research, Brisbane, Australia
K. Butt
Affiliation:
Queensland Institute of Medical Research, Brisbane, Australia
J. Osborne
Affiliation:
Department of Radiology, Royal Women's Hospital, Brisbane, Australia
G. O'Brien
Affiliation:
Department of Radiology, Royal Women's Hospital, Brisbane, Australia
*
Queensland Institute of Medical Research, Brisbane, Qld 4029, Australia.

Abstract

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We wished to establish the frequency, regularity and laterality of multiple ovulation in mothers of dizygotic (DZ) twins and controls. Subjects had regular menses and were not using oral contraceptives. Ovarian ultrasound scans were taken over a number of cycles in 21 mothers of DZ twins and 18 controls (including 13 mothers of monozygotic [MZ] twins). Multiple large follicles (≥ 12 mm diameter) were seen significantly more frequently in mothers of DZ twins (13/21 mothers, 24/77 cycles, average ± SE follicles/cycle 1.34 ± 0.11) than controls (2/18 mothers, 3/31 cycles, average 1.10±0.08). Both ipsilateral and contralateral multiple follicles were observed. In one case a mother of DZ twins showed multiple large follicles in 7 out of 10 cycles in which she was scanned, including both ipsi-and contralateral patterns of occurrence.

Keywords

Dizygotic twinningMultiple ovulationFollicular developmentOvarian ultrasound
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 40 , Issue 3-4 , October 1991 , pp. 291 - 301
Copyright
Copyright © The International Society for Twin Studies 1991

References

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