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Family History and Birthweight in Monozygotic Twins Concordant and Discordant for Psychosis

Published online by Cambridge University Press:  01 August 2014

S.W. Lewis ,
B. Chitkara ,
A.M. Reveley  and
R.M. Murray
S.W. Lewis*
Affiliation:
Institute of Psychiatry, University of London, London, UK
B. Chitkara
Affiliation:
Institute of Psychiatry, University of London, London, UK
A.M. Reveley
Affiliation:
Maudsley Hospital, London, UK
R.M. Murray
Affiliation:
Institute of Psychiatry, University of London, London, UK
*
Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK

Abstract

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In a sample of monozygotic twins, intrapair differences in reported birthweight were larger in those pairs discordant for later psychosis, compared to pairs concordant for psychosis. A trend towards less family history of psychiatric disorder was also found in the discordant pairs.

Keywords

PsychosisBirthweightMZ Twins
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 36 , Issue 2 , April 1987 , pp. 267 - 273
Copyright
Copyright © The International Society for Twin Studies 1987

References

REFERENCES

1.Andreasen, NC, Rice, J, Endicott, J, Reich, T, Coryell, W (1986): The family history approach to diagnosis. Arch Gen Psychiatry 43:421–429.Google Scholar
2.Eaves, LJ, Kendler, KS, Schulz, SC (1986): The familial sporadic classification: Its power for the resolution of genetic and environmental aetiologic factors. J Psychiatr Res 20:115–130.CrossRefGoogle Scholar
3.Gershon, ES, Hamovit, JJ, Guraff, JJet al (1982): A Family stydy of schizoaffective, bipolar 1, bipolar 2, unipolar and normal control probands. Arch Gen Psychiatry 39:1157–1167.CrossRefGoogle Scholar
4.Gottesman, II, Shields, J (1972): Schizophrenia and Genetics: A Twin Study Vantage Point. New York: Academic Press.Google Scholar
5.Gottesman, II, Shields, J (1977): Obstetric complications and twin studies of schizophrenia: Clarifications and affirmations. Schizophrenia Bull 3:351–354.Google Scholar
6.Gottesman, II, Shields, J (1982): Schizophrenia: The Epigenetic Puzzle. Cambridge: Cambridge University Press.Google Scholar
7.Kringlen, E (1967): Heredity and Environment in the Functional Psychoses. London: William Heinemann.Google Scholar
8.Kringlen, E (1986): Status of twin research in functional psychoses. Psychopathol 19:85–92.Google Scholar
9.Lewis, SW, Reveley, AM, Reveley, MA, Chitkara, B, Murray, RM (1987) The familial sporadic distinction as a strategy in schizophrenia research. Br J Psychiatry, in press.Google Scholar
10.McGue, M, Gottesman, II, Rao, DC (1983): The transmission of schizophrenia under a multifactorial threshold model. Am J Hum Genet 35:1161–1178.Google Scholar
11.McNeil, TF, Kaij, L (1978): Obstetric factors in the development of schizophrenia: complications in the births of preschizophrenics and in reproduction by schizophrenic parents. In Wynne, LC, Cromwell, RL, Matthysse, S (eds): The Nature of Schizophrenia. New York: Wiley.Google Scholar
12.Mosher, LR, Pollin, W, Stabenau, JR (1971): Identical twins discordant for schizophrenia. Arch Gen Psychiatry 24:422–430.Google Scholar
13.Murray, RM, Lewis, SW, Reveley, AM (1985): Towards an aetiological classification of schizophrenia. Lancet i: 1023–6.Google Scholar
14.Reveley, AM, Reveley, MA, Clifford, CA, Murray, RM (1982): Cerebral ventricular size in twins discordant for schizophrenia. Lancet i:50–541.Google Scholar
15.Reveley, AM, Reveley, MA, Murray, RM (1984): Cerebral ventricular enlargement in non-genetic schizophrenia: A controlled twin study. Br Psychiatry 144:89–93.Google Scholar
16.Reich, T, Cloninger, CR, Guze, SB (1975): The multifactorial model of disease trasmission: description of the model and its use in psychiatry. Br J Psychiatry 127:1–10.CrossRefGoogle Scholar
17.Robbins, LC (1963): The accuracy of parental recall of aspects of childdevelopment and of child rearing practices. J Abnorm Soc Psychol 66:262–270.Google Scholar
18.Rosanoff, AJ, Handy, LM, Plesset, I, Brush, S (1934): The etiology of so-called schizophrenic psychoses with special reference to their occurrence intwins. Am J Psychiatry 91:247–286.CrossRefGoogle Scholar
19.Rosenthal, D (1959): Some factors associated with concordance anddiscordance with respect to schizophrenia in monozygotic twins. J Nerv MentDis 129:1–10.CrossRefGoogle Scholar
20.Slater, E (1953): Psychotic and Neurotic Illnesses in Twins. MedicalResearch Council Special Report, Series No. 278. London: Her Majesty'sStationery Office.Google Scholar
21.Spillman, JR, (1987): Birthweight effects on twin temperament and maternal rewards. Acta Genet Med Gemellol, in press.Google Scholar
22.Spitzer, R, Endicott, J, Rogins, E (1975): Research Diagnostic Criteria, Instrument No. 58. New York: NY State Psychiatric Institute.Google Scholar
23.Tienari, P (1963): Psychiatric illnesses in idendical twins. Acta Psychiatr Scand Suppl 171:9–195.Google Scholar
24.Torgersen, S (1979): The determination of twin zygosity by means of a mailed questionnaire. Acta Genet Med Gemellol 28:225–236.Google Scholar
25.Torrey, EF (1977): Birth weights perinatal insults and HLA types: return to “original din”. Schizophr Bull 3:347–351.CrossRefGoogle ScholarPubMed