Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2024-12-28T06:14:40.956Z Has data issue: false hasContentIssue false
  • English
  • Français

A Family Study of Developmental Effects upon Blood Pressure Variation

Published online by Cambridge University Press:  01 August 2014

J. Sims ,
D. Carroll ,
J.K. Hewitt  and
J.R. Turner
J. Sims*
Affiliation:
Department of Psychology, University of Birmingham, UK Department of Human Genetics, Medical College of Virginia, Richmond, USA
D. Carroll
Affiliation:
Department of Psychology, University of Birmingham, UK Department of Human Genetics, Medical College of Virginia, Richmond, USA
J.K. Hewitt
Affiliation:
Department of Psychology, University of Birmingham, UK Department of Human Genetics, Medical College of Virginia, Richmond, USA
J.R. Turner
Affiliation:
Department of Psychology, University of Birmingham, UK Department of Human Genetics, Medical College of Virginia, Richmond, USA
*
P.O. Box 363, Department of Psychology, University of Birmingham, UK

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

In an earlier study of blood pressure variation in middle aged parents and their young adult twin offspring, the greater blood pressure variation observed in the parent sample was accounted for in terms of an increasing influence of individual environmental experiences with increasing age and a commensurate reduction in the impact of heredity. In the present study, the sample size was enlarged to provide a more powerful test of these effects. Maximum likelihood model-fitting techniques were applied to blood pressure covariation in balanced pedigrees, consisting of 85 families (40 MZ and 45 DZ twin pairs). As before, our analysis indicated that a developmental effect was a salient factor in the older age group.

Keywords

Blood pressureTwin family designHeredityAgeDevelopmental effectsIndividual environment
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 36 , Issue 4 , October 1987 , pp. 467 - 473
Copyright
Copyright © The International Society for Twin Studies 1987

References

REFERENCES

1. Borhani, A, Feinleib, M, Garrison, RJ, Christian, JC, Rosenman, RH (1976): Genetic variance in blood pressure. Acta Genet Med Gemellol 25:137–144.Google Scholar
2. Carroll, D, Hewitt, JK, Last, KA, Turner, JR, Sims, J (1985): A twin study of cardiac reactivity and its relationship to parental blood pressure. Physiol Behav 34:103–106.Google Scholar
3. De Faire, U, Iselius, L, Lundman, T (1982): Biological and cultural determinants of blood pressure. Hypertension 4:725–728.Google Scholar
4. Evans, JG, Rose, G (1971): Hypertension. Br Med Bull 27:37–42.CrossRefGoogle ScholarPubMed
5. Feinleib, M, Garrison, RJ (1979): The contribution of family studies to the partitioning of population variance of blood pressure. In Sing, CF, Skolnick, M (eds): Genetic Analysis of Common Diseases: Application to Predictive Factors in Coronary Heart Disease. New York: AR Liss p 653.Google Scholar
6. Feinleib, M, Garrison, RJ, Borhani, N, Rosenman, RH, Christian, JC (1975): Studies of hypertension in twins. In Oglesby, P (ed): Epidemiology and Control of Hypertension. Miami: Symposia Specialists, pp 3–20.Google Scholar
7. Harburg, E, Schork, MA, Erfurt, JC, Schull, WJ, Chape, C (1977): Heredity, stress and blood pressure, a family set method - II: Results of blood pressure measurement. J Chron Dis 30:649–658.CrossRefGoogle ScholarPubMed
8. Harlan, WR, Osborne, RK, Graybiel, A (1962): A longitudinal study of blood pressure. Circulation 26:530–543.CrossRefGoogle Scholar
9. Havlik, RJ, Garrison, RJ, Feinleib, M, Padgett, S, Castelli, WP, McNamara, PM (1979): Blood pressure aggregation in families. Am J Epidemiol 106:304–310.CrossRefGoogle Scholar
10. Havlik, RJ, Feinleib, M (1982): Epidemiology and genetics of hypertension. Hypertension 4 (Suppl III): 121–127.Google Scholar
11. Joreskog, KG, Sorbom, D (1984): Lisrel VI: Users Guide. Moresville, Indiana: Scientific Software Inc.Google Scholar
12. Kotchen, JM, Kotchen, TA, Guthrie, GP, Cottrill, CM, McKean, HE (1980): Correlates of adolescent blood pressure at five-year follow-up. Hypertension 2 (Suppl I): 124–129.CrossRefGoogle ScholarPubMed
13. Kotchen, JM, McKean, HE, Kotchen, TA (1982): Blood pressure trends with ageing. Hypertension 4: (Suppl III): 128–134.Google Scholar
14. Rose, RJ, Miller, JZ, Grim, CE, Christian, JC (1979): Aggregation of blood pressure in the families of identical twins. Am J Epidemiol 109:503–511.Google Scholar
15. Sims, J, Hewitt, JK, Kelly, KA, Carroll, D, Turner, JR (1986): Familial and individual influences on blood pressure. Acta Genet Med Gemellol 35:7–21.Google Scholar
16. Tyroler, HA (1977): The Detroit project studies of blood pressure: A prologue and review of related studies and epidemiological issues. J Chron Dis 30:613–624.Google Scholar