Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-10T12:07:36.488Z Has data issue: false hasContentIssue false
  • English
  • Français

Magnetic Resonance Imaging of Cerebral Central Sulci: a Study of Monozygotic Twins

Published online by Cambridge University Press:  01 August 2014

I. Bonan ,
A.M. Argenti ,
M. Duyme ,
D. Hasboun ,
A. Dorion ,
C. Marsault  and
A. Zouaoui
I. Bonan
Affiliation:
Department of Neuroradiology
A.M. Argenti*
Affiliation:
Department of Biological Anthropology and Genetic Epidemiology, INSERM U155, Paris
M. Duyme
Affiliation:
Department of Biological Anthropology and Genetic Epidemiology, INSERM U155, Paris
D. Hasboun
Affiliation:
Department of Neurology (D.H.) Pitié-Salpêtrière Hospital, University of Paris VI, Paris, France
A. Dorion
Affiliation:
Department of Biological Anthropology and Genetic Epidemiology, INSERM U155, Paris
C. Marsault
Affiliation:
Department of Neuroradiology
A. Zouaoui
Affiliation:
Department of Neuroradiology
*
Unité d'Epidémiologie Génétique INSERM U155, Case 7041, Université de Paris VII, 75005, Paris, France; e-mail: argenti@ccr.jussieu.fr.

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The cerebral central sulci, seat of the sensorimotor cortex, vary anatomically in form, length and depth among individuals and present a left/right asymmetry. The purpose of this work was to measure central sulcus's lengths, at the surface and in-depth, in each hemisphere of monozygotic twins in order to evaluate the influence of environmental factors on the morphometry and asymmetry of this structure. A measurement technique on MR images of the brains using 3 D software was developed. Two operators applied this technique to measure central sulcus lengths at the surface of the brain and in-depth in each hemisphere. Besides the fact that the technique developed gave high Intraclass Correlation Coefficients (ICC) for the surface lengths (mean value 0.94), and slightly less high for the in-depth length (mean value 0.87), we found a weak (from 0.57 to 0.73 for raw data) but significant ICC between homologous sulci in pairs of twins. In addition, the ICC for asymmetry indices were not significant. Hence, if central sulcus morphometry is in part genetically influenced, these results show that nongenetic factors are nonetheless important in their development.

Keywords

TwinsBrainAsymmetryCentral sulcusGenetics
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 47 , Issue 2 , April 1998 , pp. 89 - 100
Copyright
Copyright © The International Society for Twin Studies 1998

References

REFERENCES

1.Bartley, AJJones, DWWeinberger, DR (1997): Genetic variability of human brain size and cortical gyral patterns. Brain 120: 257–269.Google Scholar
2.Biondi, A, Noqueira, H, Dormont, Det al. (1998): Are the brains of monozygotic twins similar? A three-dimensionnal MR study. Am J Neuroradio 19: 1361–1367.Google Scholar
3.Cannelli, D, DeCarli, C, Swan, GEet al. (1998): Evidence for genetic variance in white matter hyperintensity volume in normal elderly male twins. Stroke 29: 1177–1181.Google Scholar
4.Cheverud, JMFalk, D, Vannier, Met al. (1990): Heritability of brain size and surface feature in Rhesus macaques (macaca mulatla). J Hered 81: 51–71.Google Scholar
5.Chi, JGDooling, ECGilles, FH (1977): Gyral development of brain. Annals of Neurology 1: 86–93CrossRefGoogle Scholar
6.Clarisse, J, Ares, GSPertuzon, Bet al. (1997): Repérage du sillon central en scanner et en IRM. J Neuroradiol 24: 187–204.Google Scholar
7.Graf, D, Keyserlink, V, Niemann, Ket al. (1988): A quantitative approach to spatial variations of human cerebral sulci. Acta Anat 131: 127–131.Google Scholar
8.Hasboun, D, Chantome, M, Zouaoui, Aet al. (1996): Evaluation du volume cérébral: reproductibilité et précision d'une technique 3D IRM. Bull, et Mem. de la Société d'Anthropologie de Paris 8: 43–56.Google Scholar
9.Leamy, L (1988): Genetic and maternal influences on brain and body size in randombred house mice. Evolution 42: 42–53.Google Scholar
10.Le Goualher, G, Barillot, C (1997): Modeling cortical sulci with active ribbons. International Journal of Pattern Recognition and Artificial Intelligence 11–8: 1295–1315.CrossRefGoogle Scholar
11.Naidich, T, Brightbill, TC (1996): Systems for localizing fronto-parietal gyri and sulci on axial CT and MRI. International Journal of Neuroradiology 4: 313–338.Google Scholar
12.Ono, M, Kubik, S, Abernathy, CD (1990): Atlas of cerebral sulci. New York: Georg Thieme Verlag.Google Scholar
13.Oppenheim, JSSkerry, JFTramo, MJet al. (1989): Magnetic resonance imaging morphology of the corpus callosum in MZT. Annals of Neurology 26: 100–104.Google Scholar
14.Riska, B, Atchley, WR (1985): Genetics of growth predict patterns of brain size evolution. Science 229: 668–671.Google Scholar
15.Roderick, THWiner, RFWiner, CCet al. (1973): Genetic and phenotypic variation in weight of brain and spinal cord between inbred strains of mice. Brain Research 64: 345–353.Google Scholar
16.Sarna, S, Kaprio, J, Sistonen, Pet al. (1972): Diagnosis of twin zygosity by mailed questionnaire. Hum Hered 28: 241–254.Google Scholar
17.Steinmetz, H, Herzog, A, Schlaug, Get al. (1995): Brain (a)symmetry in Monozygotic Twins. Cerebral Cortex 5: 296–300.Google Scholar
18.Tramo, JTLoftus, WCThomas, CEet al. (1995): Surface area of human cerebral cortex and its gross morphological subdivisions: in vivo measurements in monozygotic twins suggest differential hemisphere effects of genetic factors. J Cogn Neurosci 7: 2, 292–301.Google Scholar
19.Tramo, MJLoftus, WCStuckel, TAet al. (1998): Brain size, head size, and intelligence quotient in monozygotic twins. Neurology 50: 1246–1252.Google Scholar
20.Vannier, MWBrunsden, BSHildebolt, CFet al. (1991): Brain surface cortical sulcal lengths: quantification with three-dimensional MR imaging. Radiology 180: 479–484.Google Scholar
21.Weinberger, DRBartley, AJJones, DWet al. (1992): Regional cortical gyral variations in human monozygotic twins (abstr). Soc Neurosci Abstr 18: 595.Google Scholar
22.Welker, W (1990): Why does the cerebral cortex fissure and fold? A review of determinants of gyri and sulci. In Peters, A, Jones, KG eds. Cerebral Cortex. Comparative structure and evolution of cerebral cortex, Part II. New York: Plenum 8B: 3–136.Google Scholar
23.White, LELucas, G, Richards, Purves, D (1994): Cerebral asymmetry an handeness. Nature 197–198.Google Scholar
24.White, LEAndrews, IJHulette, C, et al. (1997a): Structure of the human sensorimotor system. I: morphology and cytoachitecture of the central sulcus. Cerebral Cortex 7: 18–30.Google Scholar
25.White, LEAndrews, IJHulette, Cet al. (1997b): Structure of the human sensorimotor system. II: lateral symmetry. Cerebral Cortex 7: 31–47.Google Scholar
26.Yetkin, FZPapke, RAMark, LPet al. (1995): Location of the sensorimotor cortex: functionnal and conventional MR compared. AJNR 16: 2109–2113.Google Scholar