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Optimization Procedures in Twin Zygosity Diagnosis by Genetic Markers. A Cost-Effectiveness Analysis

Published online by Cambridge University Press:  01 August 2014

Seppo Sarna  and
Jaakko Kaprio
Seppo Sarna*
Affiliation:
Department of Public Health Science, University of Helsinki
Jaakko Kaprio
Affiliation:
Department of Public Health Science, University of Helsinki
*
Department of Public Health Science, Haartmaninkatu 3, SF-00290 Helsinki 29, Finland

Abstract

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More and more genetic markers usable for twin zygosity determination have become available. A relatively small number of markers is sufficient to achieve a satisfactory probability of correctly classifying a twin pair. Previously only the genetic properties of markers have been considered when choosing the markers to be determined. A cost-effectiveness analysis, which considers both genetic properties and relative determination costs of markers, is presented and illustrated with data from the Finnish Twin Registry studies.

Keywords

Twin zygosity diagnosisGenetic markersOptimization proceduresFinnish twin registry
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 28 , Issue 2 , April 1979 , pp. 139 - 148
Copyright
Copyright © The International Society for Twin Studies 1979

References

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