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Ovarian Hyperstimulation Syndrome May be More Likely if Multiple Pregnancy Occurs Following Assisted Conception

Published online by Cambridge University Press:  01 August 2014

R. S. Mathur ,
L. A. Joels  and
J. M. Jenkins
R. S. Mathur
Affiliation:
University of Bristol, Department of Obstetrics & Gynaecology, St. Michael's Hospital, Bristol
L. A. Joels
Affiliation:
University of Bristol, Department of Obstetrics & Gynaecology, St. Michael's Hospital, Bristol
J. M. Jenkins
Affiliation:
University of Bristol, Department of Obstetrics & Gynaecology, St. Michael's Hospital, Bristol

Abstract

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Whereas modern assisted conception with such techniques as in vitro fertilisation now helps many subfertile couples to fulfil their ambition to have a child, it has not been without a price. The increased incidence of multiple pregnancies, with their attendant maternal and perinatal sequelae following assisted conception is well known, but perinatologists may be less familiar with the Ovarian Hyperstimulation Syndrome (OHSS) which is the other major complication when controlled ovarian hyperstimulation is used during assisted conception treatment. Mild forms of OHSS are common and require no more than symptomatic treatment. Severe forms of OHSS are uncommon occurring in 0.6% to 14% of IVF cycles [15, 5], but are nonetheless very important to identify as they may lead to thrombo-embolic disease, cardiorespiratory dysfunction, renal failure and even death [6]. This review considers whether OHSS may be related to multiple pregnancy by reviewing the available literature and local experience.

Keywords

Ovarian Hyperstimulation SyndromeIn vitro fertilisationMultiple pregnancy
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 44 , Issue 3-4 , October 1995 , pp. 233 - 235
Copyright
Copyright © The International Society for Twin Studies 1995

References

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