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Possible Linkage Relationship Between Genetic Markers and Blood Magnesium and Zinc A Twin Study

Published online by Cambridge University Press:  01 August 2014

P. Darlu ,
E. Defrise-Gussenhoven ,
Y. Michotte ,
C. Susanne  and
J.G. Henrotte
P. Darlu*
Affiliation:
Groupe de Recherches de Génétique Epidémiologique, INSERM, Paris R.C.P. Magnésium et Oligoéléments, CNRS, Faculté de Pharmacie, Paris
E. Defrise-Gussenhoven
Affiliation:
Laboratorium Antropogenetika, Vrije Universiteit, Brussels
Y. Michotte
Affiliation:
Pharmaceutical Institute, Brussels
C. Susanne
Affiliation:
Laboratorium Antropogenetika, Vrije Universiteit, Brussels
J.G. Henrotte
Affiliation:
R.C.P. Magnésium et Oligoéléments, CNRS, Faculté de Pharmacie, Paris
*
Groupe de Recherches de Génétique Epidémiologique, INSERM U. 155, Château de Longchamp, 75016 Paris, France

Abstract

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In a sample of 63 like-sex dizygotic twins, red blood ceE and plasma magnesium and red blood cell zinc concentrations were analyzed for linkage to each of 23 genetic systems by estimating correlation between proportion of genes identical by descent and biological resemblance for the trait. The results suggest possible linkage of red blood cell magnesium with the HLA locus and of red blood cell zinc with the GLO1 locus. However, studies applying more powerful tests are needed to confirm such conclusions.

Keywords

LinkageMagnesiumZincTwinsSib-pair methodMarker loci
Type
Short Note
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 34 , Issue 1-2 , April 1985 , pp. 109 - 112
Copyright
Copyright © The International Society for Twin Studies 1985

References

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