Hostname: page-component-cd9895bd7-fscjk Total loading time: 0 Render date: 2024-12-26T22:42:10.222Z Has data issue: false hasContentIssue false
  • English
  • Français

Some Observations Concerning Leukemia in Twins

Published online by Cambridge University Press:  01 August 2014

Ronald P. Danis  and
Louis G. Keith
Ronald P. Danis
Affiliation:
Departments of Obstetrics and Gynecology, Northwestern University Medical School, Chicago
Louis G. Keith*
Affiliation:
Departments of Obstetrics and Gynecology, Northwestern University Medical School, Chicago Prentice Women's Hospital and Maternity Center, Chicago
*
Prentice Women's Hospital and Maternity Center, 333 Superior Street, Suite 463–5, Chicago, Illinois 60611

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The first report of leukemia occurring in both members of a twin pair was by Seigel in 1928. Since this time many more case reports and epidemiologic studies have appeared in the literature. In recent years, however, published reports on leukemia in twins have been less common. This waning interest is certainly not due to overstudy, since even the most basic questions concerning the occurrence of leukemia in twins have yet to be definitively answered. Apparently, research on this subject is at an impasse due to the difficulty of obtaining study populations and the lack of substantial experimental data in the records of the few twin registries in existence. This report represents an update on the observations and comments on this subject begun in 1970 by Keith and Brown [4].

Keywords

LeukemiaTwinsConcordanceDiscordance
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 31 , Issue 3-4: Special Issue on Twin Pregnancies , July 1982 , pp. 173 - 177
Copyright
Copyright © The International Society for Twin Studies 1982

References

REFERENCES

1. Pearson, HA, Grello, FW, Cone, TE (1963): Leukemia in identical twins. New Engl J Med 268:1151–6.Google Scholar
2. Miller, RW (1971): Deaths from childhood leukemia and solid tumors among twins and other sibs in the U.S., 1960–67. J Natl Cancer Inst 46:203–209.Google Scholar
3. Hewitt, D, Lashof, JC, Stewart, AM (1966): Childhood cancer in twins. Cancer 19:157–161.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
4. Keith, L, Brown, E (1971): Epidemiologic study of leukemia in twins (1928–1969). Acta Genet Med Gemellol 20:1–22.Google Scholar
5. Keith, L, Brown, E, Fields, C (1970): A review: Perinatal-congenital leukemia in twins. Chicago Med School Quart 29:1–8.Google Scholar
6. Draper, GJ, Heaf, MM, Wilson, LM (1977): Occurrence of childhood cancers among sibs and estimation of familial risk. J Med Genet 14:81–90.CrossRefGoogle Scholar
7. Li, FP, Tucker, ME, Fraumeni, JF Jr (1976): Childhood cancer in sibs. J Pediatr 88:419–23.Google Scholar
8. Zuelzer, WW, Cox, DE (1969): Genetic aspects of leukemia. Semin Hematol 6:228–249.Google Scholar
9. Felleta, JM, Starling, KA, Fernbach, DJ (1973): Leukemia in twins. Pediatrics 52:846–49.CrossRefGoogle Scholar
10. Jackson, EW, Norris, FD, Klauber, MR (1969): Childhood leukemia in California-born twins. Cancer 23:913–919.Google Scholar
11. Miller, RW (1967): Persons with exceptionally high risk of leukemia. Cancer Res 27:2420–23.Google Scholar
12. MacMahon, B, Levy, MA (1964): Prenatal origin of childhood leukemia. New Engl J Med 270:1082–85.Google Scholar
13. Keith, L, Brown, ER, Fields, C, Stepto, R (1973): Age group differences of twins with leukemia. Bibl Haemetol (Basel) 39:1125–1135.Google ScholarPubMed
14. Schmitt, TA, Degos, L (1978): Leucemies familiales. Bull Cancer (Paris) 65:83–8.Google Scholar
15. Keith, L, Brown, ER, Ames, B, Stotsky, M (1976): Possible obstetrical factors effecting leukemia in twins. Bibl Haemetol (Basel) 43:221–223.Google Scholar
16. Hilton, HB, Lewis, K, Trowell, HR (1970): Group trisomy in identical twins with acute leukemia. Blood 35:222–226.Google Scholar
17. Kucera, J (1972): Concordance of leukemia and twinning in Down's syndrome families. (Letter), Lancet 1:150.CrossRefGoogle ScholarPubMed
18. Svarch, E, De la Torre, E (1977): Myelomonocytic leukemia with a preleukoemia syndrome and Ph 1 chromosome in monozygotic twins. Arch Dis Child 52:72–74.Google Scholar
19. Bauke, J (1969): Chronic myelocytic leukemia. Chromosome studies of a patient and his nonleukemic identical twin. Cancer 24:643–648.3.0.CO;2-6>CrossRefGoogle ScholarPubMed
20. Clarkson, BD, Boyse, EA (1971): Possible explanation for the high concordance for acute leukemia in monozygotic twins. Lancet 1:699–701.Google Scholar
21. Sikov, MR (1971): Carcinogenesis following prenatal exposure to radiation. Biol Res Pregnancy 2:159–167.Google Scholar
22. Rigby, PG, Hanson, TA, Smith, RS (1964): Passage of leukemic cells across the placenta. New Engl J Med 271:124–127.Google Scholar
23. Yunis, JJ, Bloomfield, CD, Ersrud, K (1981): All patients with acute nonlymphocytic leukemia may have a chromosomal defect. New Engl J Med 305:135–139.CrossRefGoogle ScholarPubMed
24. Spiegelman, S, Baxt, W, Kufe, D, Peters, WP, Schlom, J (1975): Sequences related to the RNA tumor viruses in the RNA and DNA of human leukemias and lymphomas. Bibl Haemetol (Basel) 40:3–25.Google Scholar
25. Knudson, AG Jr (1973): Leukemia-specific DNA and twins. (Letter), Lancet 2:1032.Google Scholar
26. Baxt, W, Yates, JW, Wallace, HJ Jr, Holland, JF, Spiegelman, S (1973): Leukemia—specific DNA sequences in leukocytes of the leukemic member of identical twins. Proc Natl Acad Sci USA 70:2629–32.Google Scholar
27. Mavligit, GW, Gutterman, JU, Hersh, EM, Rossen, RD, Butler, WT, McCredie, KB, Freireich, EJ (1973): Lymphoma associated HLA antigens in the mixed leucocyte reactivity between identical siblings. Transplantation 16:217–20.Google Scholar
28. Fefer, A, Mickelson, E, Thomas, ED (1974): Leukemia antigens: Mixed leucocyte culture tests on twelve leukemic patients with identical twins. Clin Exp Immunol 18:237–42.Google ScholarPubMed
29. Rosenberg, EB, Herberman, RB, Levine, PH, Halterman, RH, McCoy, JL, Wunderlich, JR (1972): Lymphocyte cytotoxicity reactions to leukemia associated antigens in identical twins. Int J Cancer 9:648–58.Google Scholar
30. Han, T, Wang, J (1972): ‘Antigenic’ disparity between leukaemic lymphoblasts and normal lymphocytes in identical twins. Clin Exp Immunol 12:171–5.Google Scholar
31. Levine, PH, Herberman, RB, Rosenberg, EB, McClure, PD, Roland, A, Dienta, RJ, Ting, RC (1972): Acute leukemia in identical twins: Search for viral and leukemia-associated antigens. J Natl Cancer Inst 49:943–52.Google Scholar
32. Fefer, A, Einstein, AB, Thomas, ED, Buckner, CD, Clift, RA, Glucksberg, H, Neiman, PE, Storb, R (1974): Bone-marrow transplantation for hematologic neoplasia in 16 patients with identical twins. N Engl J Med 290:1389–93.Google Scholar
33. Fefer, A, Buckner, CD, Clift, RA, Fass, L, Glucksberg, H, Mickelson, EM, Neiman, P, Storb, R, Thomas, ED (1973): Marrow grafting and immunotherapy in identical twins with hemotologic malignancies. Trans Assoc Am Phys 86:178–84.Google Scholar
34. Raccuglia, G, Lansing, A (1973): Spleen transplantation in a leukemic individual from his healthy identical twin. Clin Exp Immunol 14:1–18.Google Scholar
35. Fefer, A, Buckner, CD, Clift, RA, Fass, L, Lerner, KG, Mickelson, EM, Neiman, P, Rudolph, R, Storb, R, Thomas, ED (1973): Marrow grafting in identical twins with hematologic malignancies. Transplant Proc 5:927–31.Google Scholar
36. Bortin, MM, Rimm, AA (1978): Bone marrow transplantation for AML. JAMA 240:1245–52.Google Scholar
37. Fefer, A, Buckner, CD, Thomas, ED, Cheewer, MA, Clift, RA, Glucksberg, H, Neiman, PE, Storb, R (1977): Cure of hematologic neoplasia with transplantation of marrow from identical twins. New Engl J Med 297:146–8.Google Scholar
38. Fefer, A, Cheever, MA, Greenberg, PD, Appelbaum, FR, Boyd, CN, Buckner, CD, Kaplan, HG, Ramberg, R, Sanders, JE, Storb, R, Thomas, ED (1982): Treatment of CGL with chemo-radiotherapy and transplantation of marrow from identical twins. New Engl J Med 306:63–8.Google Scholar
39. Stewart, A (1971): Low dose radiation cancers in man. Adv Cancer Res 14:359–390.Google Scholar