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Canine distemper, a re-emerging morbillivirus with complex neuropathogenic mechanisms

Published online by Cambridge University Press:  28 February 2007

Christian Griot ,
Marc Vandevelde ,
Martina Schobesberger  and
Andreas Zurbriggen
Christian Griot*
Affiliation:
Institute of Virology and Immunoprophylaxis, Swiss Federal Veterinary Office, 3147 Mittelhäusern, University of Bern, 3012 Bern, Switzerland Institute of Animal Neurology, University of Bern, 3012 Bern, Switzerland
Marc Vandevelde
Affiliation:
Institute of Animal Neurology, University of Bern, 3012 Bern, Switzerland
Martina Schobesberger
Affiliation:
Institute of Animal Neurology, University of Bern, 3012 Bern, Switzerland
Andreas Zurbriggen
Affiliation:
Institute of Animal Neurology, University of Bern, 3012 Bern, Switzerland
*
*Institute of Virology and Immunoprophylaxis, P.O. Box 17, Sensemattstrasse 293, CH-3147 Mittelhäusern, Switzerland E-mail: Christian.Griot@ivi.admin.ch Fax: +41(0)31 848 9222
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Abstract

Paramyxoviruses are responsible for a wide variety of diseases both in humans and in animals. Common to many paramyxoviruses is the fact that they can cause neurological symptoms in their final host. Newly discovered paramyxoviruses, such as the Hendra and Nipah viruses, show the same pattern of pathogenesis as that of the paramyxoviruses already known. Canine distemper virus (CDV) is a well-studied member of the genus Morbillivirus. Study of the neuropathogenesis of CDV might give insight into disease mechanisms and suggest approaches for the prevention of other recently discovered paramyxovirus infections.

Keywords

canine distempermorbillivirusdogshenipahneuropathology
Type
Research Article
Information
Animal Health Research Reviews , Volume 4 , Issue 1 , June 2003 , pp. 1 - 10
Copyright
Copyright © CAB International 2003

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