Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-13T04:57:49.208Z Has data issue: false hasContentIssue false
  • English
  • Français

The potential of Nigerian bioactive plants for controlling gastrointestinal nematode infection in livestock

Published online by Cambridge University Press:  01 June 2016

Isaiah Oluwafemi Ademola
Isaiah Oluwafemi Ademola*
Affiliation:
Department of Veterinary Microbiology and Parasitology, University of Ibadan, Ibadan, Nigeria
*
Corresponding author. E-mail: io.ademola@ui.edu.ng
Get access Rights & Permissions [Opens in a new window]

Abstract

Bioactive compounds from marine and terrestrial organisms have been used extensively in the treatment of many diseases in both their natural form and as templates for synthetic modifications. This review summarizes present knowledge about anthelmintic effects of the extracts of bioactive plants in Nigeria against helminth parasites of ruminants. Plants traditionally used in livestock production are discussed. The main focus is hinged on in vitro and in vivo activities of secondary plant metabolites against nematodes of livestock. This review provides insight into preliminary studies of medicinal plants, which can be investigated further to discover promising molecules in the search for novel anthelmintic drugs and nutraceuticals.

Keywords

anthelminticnematodesbioactive plantsNigeria
Type
Review Article
Information
Animal Health Research Reviews , Volume 17 , Issue 2 , December 2016 , pp. 85 - 91
Check for updates
Copyright
Copyright © Cambridge University Press 2016 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Adamu, M, Oshadu, OD and Ogbaje, CI (2010). Anthelminthic efficacy of aqueous extract of Acanthus montanus leaf against strongylid nematodes of small ruminants. African Journal of Traditional Complementary and Alternative Medicine 7: 279–285.Google ScholarPubMed
Addae-Mensah, I and Munenge, RW (1989). Quercetin-3-neohesperidose (rutin) and other flavonoids as the active hypoglyeaemic agents in Bridelia ferruginae . Fitoterapia 9: 359–362.Google Scholar
Adebowale, EA (1997). Proceedings of a Workshop on Indigenous Knowledge in Agriculture and Rural Development. Organized by the South West Zonal farming systems research and extension. IAR&T. Obafemi Awolowo University, Moor Plantation, Ibadan, Nigeria.Google Scholar
Ademola, IO (2002). A survey on Ivermectin resistance in strongyles of sheep in Oyo State, Nigeria, using a larval development assay. Israel Journal of Veterinary Medicine 57: 149–151.Google Scholar
Ademola, IO and Eloff, JN (2010). In vitro anthelmintic activity of Combretum molle (R. Br. ex G. Don) (Combretaceae) against Haemonchus contortus ova and larvae. Veterinary Parasitology 169: 198–203.CrossRefGoogle Scholar
Ademola, IO and Eloff, JN (2011a). Anthelminthic activity of acetone extract and fractions of Vernonia amygdalina against Haemonchus contortus eggs and larvae. Tropical Animal Health and Production 43: 521–527.CrossRefGoogle ScholarPubMed
Ademola, IO and Eloff, JN (2011b). In vitro anthelmintic effect of Anogeissus leiocarpus (dc.) guill. & perr. leaf extracts and fractions on developmental stages of Haemonchus contortus . African Journal of Traditional Complementary and Alternative Medicine 8: 134–139.Google ScholarPubMed
Ademola, IO and Eloff, JN (2011c). Ovicidal and larvicidal activity of Cassia alata leaf acetone extract and fractions on Haemonchus contortus: in vitro studies. Pharmaceutical Biology 49: 539–544.CrossRefGoogle ScholarPubMed
Ademola, IO and Eloff, JN (2011d). Anthelmintic efficacy of cashew (Anarcadium occidentale L.) on in vitro susceptibility of the ova and larvae of Haemonchus contortus . African Journal of Biotechnology 10: 9700–9705.Google Scholar
Ademola, IO and Idowu, SO (2006). Evaluation of the anthelmintic activity of Leucaena leucocephala seed aqueous extract on Haemonchus contortus infective larvae. Veterinary Record 158: 485–486.CrossRefGoogle Scholar
Ademola, IO, Fagbemi, BO and Idowu, SO (2004). Evaluation of the anthelmintic activity of Khaya senegalensis against gastrointestinal nematodes of sheep: in vitro and in vivo studies. Veterinary Parasitology 122: 151–164.CrossRefGoogle ScholarPubMed
Ademola, IO, Akanbi, AI and Idowu, SO (2005a). Anthelmintic activity of Leucaena leucocephala chromatographic seed fractions on gastrointestinal sheep nematodes. Pharmaceutical Biology 45: 599–604.CrossRefGoogle Scholar
Ademola, IO, Fagbemi, BO and Idowu, SO (2005b). Anthelmintic activity of Spondias mombin against gastrointestinal nematodes of sheep: in vitro and in vivo studies. Tropical Animal Health and Production 37: 223–235.CrossRefGoogle Scholar
Ademola, IO, Fagbemi, BO and Idowu, SO (2007a). Evaluation of the anthelmintic activity of Nauclea latifolia leaf extract against gastrointestinal nematodes of sheep: in vitro and in vivo studies. African Journal of Traditional Complementary and Alternative Medicine 4: 148–156.Google Scholar
Ademola, IO, Fagbemi, BO and Idowu, SO (2007b). Anthelmintic activity of Spigelia anthelmia extract against gastrointestinal sheep nematodes. Parasitology Research 101: 63–69.CrossRefGoogle Scholar
Ademola, IO, Fagbemi, BO and Idowu, SO (2009). Bioseparation and activity of Khaya senegalensis fractions against Infective Larvae of Haemonchus contortus . Veterinary Parasitology 165: 170–174.CrossRefGoogle ScholarPubMed
Ademola, IO, Krücken, J, Ramünke, S, Demeler, J and von Samson-Himmelstjerna, G (2015). Absence of detectable benzimidazole resistance alleles in Haemonchus placei in cattle in Nigeria revealed by pyrosequencing of β-tubulin isotype 1. Parasitology Research 114: 1997–2001.CrossRefGoogle ScholarPubMed
Adjanahoun, E, Ahyi, MRA, Ake-Assi, L, Elewude, JA, Fadoju, SO, Gbile, ZO, Goudole, E, Johnson, CLA, Keita, A, Morakinyo, O, Ojewole, JAO, Olatunji, AO and Sofowora, EA (1991). Traditional Medicine and Pharmacopoeia. Contribution to Ethnobotanical Floristic Studies in Western Nigeria. Lagos, Nigeria: Publication of the Organization of African Unity, Scientific Technical and Research Commission, pp. 420.Google Scholar
Agaie, BM and Onyeyili, PA (2011). In vitro anthelmintic activity of the aqueous leaf extract of Anogeissus leiocarpus and its phytochemical, proximate and elemental contents. Journal of Medicinal Plant Research 5: 6656–6661.CrossRefGoogle Scholar
Ajayi, I, Ademola, IO and Okotie, SV (2008). Larvicidal effect of Aframomum danieli seed extracts against gastrointestinal nematode of sheep: in vitro studies. African Journal of Traditional Complementary and Alternative Medicine 5: 244–246.Google ScholarPubMed
Alawa, CBI, Adamu, AM, Gefu, JO, Ajanusi, OJ, Abdu, PA and Chiezey, NP (2010). In vivo efficacy of Vernonia amygdalina (compositae) against natural helminth infection in Bunaji (Bos indicus) calves. Pakistan Veterinary Journal 30: 215–218.Google Scholar
Anjara, J (1996). Ethnoveterinary pharmacology in India: past, present and future. In: Mc corkle, CM, Mathia, E and schillhorn van veen, TW (eds) Ethnoveterinary Research and Development. London: Intermidiate Technology, Publication, pp. 137–147.CrossRefGoogle Scholar
Assis, LM, Bevilaqua, CML, Morais, SM, Vieira, LS, Costa, CTC and Souza, JAL (2003). Ovicidal and larvicidal activity in vitro of Spigelia anthelmia Linn. extracts on Haemonchus contortus . Veterinary Parasitology 117: 43–49.CrossRefGoogle ScholarPubMed
Asuzu, IU and Njoku, CJ (1996). The anthelmintic effect of Alstonia boonia and Nauclea latifolia leaf aqueous extracts on Trichostrongylus infective larvae. Fitoterapia 3: 220–222.Google Scholar
Athanasiadou, S, Kyriazakis, I, Jackson, F and Coop, RL (2001). Direct anthelmintic effects of condensed tannins towards different gastrointestinal nematodes of sheep: in vitro and in vivo studies. Veterinary Parasitology 1996; 99: 205–219.CrossRefGoogle ScholarPubMed
Ayensu, ES (1978). Medicinal Plants of West Africa. Algonac, MI: Michigan Reference Publication Inc.Google Scholar
Datsu, KR, Slyaranda, BA, Wycliff, A and Fanna, IA (2011). Preliminary phytochemical screening and in vitro anthelmintic effects of aqueous extracts of Salvadora persica and Terminalia avicennoides against strongyline nematodes of small ruminants in Nigeria. Journal of Animal and Veterinary Advances 10: 437–442.Google Scholar
Ekeanyanwu, RC and Etienajirhevwe, OF (2012). In vitro anthelmintic potentials of Xylopia aethiopica and Monodora myristica from Nigeria. African Journal of Biochemistry Research 6: 115–120.CrossRefGoogle Scholar
Fashanu, SO and Fagbemi, BO (2003). A preliminary investigation of resistance to anthelmintics in strongyles of cattle in Shaki, Nigeria. African Journal of Biomedical Research 6: 111–112.Google Scholar
Hoste, H, Martinez-Ortiz-De-Montellano, C, Manolaraki, F, Brunet, S, Ojeda-Robertos, N, Fourquaux, I, Torres-Acosta, JFJ and Sandoval-Castro, CA (2012). Direct and indirect effects of bioactive tannin-rich tropical and temperate legumes against nematode infections. Veterinary Parasitology 186: 18–27.CrossRefGoogle ScholarPubMed
Ibrahim, MA (1986). Veterinary traditional practices in Nigeria. In: von Kaufmann, R, Chater, S and Blench, R (eds) Livestock System Research in Nigeria's Subhumid zone. Proceedings of the 2nd ILCA/NAPRI Symposium held in Kaduna, Nigeia, 29th October–2nd November 1984, International Livestock Centre for Africa (ILCA), P.O. Box 5689, AddisAbaba, Ethiopia, pp. 189–203.Google Scholar
Iwu, MM (1986). African Ethnomedicine. Enugu, Nigeria: USP Press, pp. 134–136.Google Scholar
Iwu, MM (1993). CRC Hand Book of African Medicinal Plants. Boca Raton, Ann Arbor, London, Tokyo: CRC Press.Google Scholar
Kabore, A. and Belem, AM (2009). Gaston, Tamboura Hamidou H, Traore Amadou, Sawadogo Laya. In vitro anthelmintic effect of two medicinal plants (Anogeissus leiocarpus and Daniellia oliveri) on Haemonchus contortus, an abosomal nematode of sheep in Burkina Faso. African Journal of Biotechnology 8: 4690–4695.Google Scholar
Kundu, S, Roy, S and Lyndem, LM (2014). Broad spectrum anthelmintic potential of Cassia plants. Asian Pacific Journal of Tropical Biomedicine 4: S436–S441.CrossRefGoogle ScholarPubMed
Lasisi, AA and Kareem, SO (2011). Evaluation of anthelmintic activity of the stem bark extract and chemical constituents of Bridelia ferruginae (Benth) Euphorbiaceae. African Journal of Plant Sciences 5: 469–474.Google Scholar
Max, RA, Wakelin, D, Craigon, J, Kassuku, AA, Kimambo, AE and Mutenga, LA (2005). Effects of two commercial preparation of condensed tannins on the survival of gastro-intestinal nematodes of mice and goats in vitro . South African Journal Animal Science 35: 213–220.Google Scholar
Mba, AH, Ogunrinade, AF and Dina, OA (1992). Benzimidazole resistance in strongyles of sheep in Ibadan, Nigeria. African Livestock Research 1: 16–17.Google Scholar
McCorkle, CM and Balazar, H (1996). Field trials in ethnoveterinary R and D; Lessons from the Andes. In: Corkle, CM, Mathias, E and Schillhorn van Veen, TW (eds) Ethnoveterinary Research and Development. London: Intermediate Technology Publication, pp. 265–282.CrossRefGoogle Scholar
Nuwanyakpa, M, Toyang, J, Njakio, H and Djangos, (1995). Forward with Ethnoveterinary and paraveterinary medicine development in the NWP Cameroon. In: Proceedings of Ethnovet Workshop. Heiter Project International. Sagba (Cameroon), pp. 16–17.Google Scholar
Nweze, NE, Ogidi, A and Ngongeh, LA (2013). Anthelmintic potential of three plants used in Nigerian ethnoveterinary medicine. Pharmaceutical Biology 51: 311–315.CrossRefGoogle ScholarPubMed
Nwosu, CO, Yakubu, S, Saleh, UA, Abdullahi, G (2006). In vitro anthehelmintic efficacy of crude aqueous extracts of neem (Azadirachta indica) leaf, stem and root on nematode. Animal Research International 3: 549–552.Google Scholar
Onocha, PA and Olusanya, TOB (2010). Antimicrobial and anthelmintic Evaluation of Nigerian Euphorbiaceae Plants 3: Acalypha wilkesiana . African Science 11: 85–89.Google Scholar
Rahmann, G (2004). Gehölzfutter – eine neue Quelle für die ökologische Tierernährung. Landbauforsch Völkenrode SH 272: 29–42.Google Scholar
Rahmann, G, Koopmann, R and Hertzberg, H (2002). Gesundheit erhalten statt Krankheit Kurieren. FORSCHUNGSReport, Verbraucherschutz, Ernährung, Landwirtschaft. Forschungs Report No. 1, pp. 4–7.Google Scholar
Sobiyi, KO and Tom Ashafa, AO (2015). In vitro anthelmintic activity of Heliotropium indicum, Senna fistula and Spigelia anthelmia used as worm expeller in South West Nigeria. Bangladesh Journal Pharmacology 10: 417–422.CrossRefGoogle Scholar
Soulsby, EJL (1982). Helminths, Arthropod and Protozoa of Domestic Animals. London: The English Language Book Society and Bailliere Tindall, 2011; pp. 238–245.Google Scholar
Suleiman, MM, Mamman, M, Yusuf, O, Aliu, YO and Ajanusi, JO (2005). Anthelmintic activity of the crude methanol extract of Xylopia aethiopica against Nippostrongylus brasiliensis in rats. Veterinary Archive 75: 487–495.Google Scholar
Suleiman, MM, Mohammed, M, Adamu, S, Eserohene, JI, Mohammad, T and Ahmad, MT (2014). Evaluation of anthelmintic activity of Nigerian ethnoveterinary plants; Cassia occidentalis and Guiera senegalensis . Veterinary World 2005 7: 536–541.CrossRefGoogle Scholar
Varghese, CG, Jacobo, PD, Georgekutty, PT and Peter, CT (1971). Use of cashew (Anacardium occidentale) nut sheet oil as an anthelmintic against ascaridiasis in the domestic fowl. Kerala Journal of Veterinary Science 2: 5–10.Google Scholar
Wahab, AR and Hiew, PP (2014). Anthelmintic activities of Spondias mombin leaves and fruits extracts against Trichostrongylid nematodes in Goats. Asian Journal of Agricultural and Food Sciences 2: 2321–1571.Google Scholar
Wahua, TAT and Oji, VI (1987). A survey of browse plants in upland areas of River State. In: Browse use and Small Ruminant Production in Southeast Nigeria. Proceedings of a Symposium held at the Federal University of Technology, Owerri, Imo State, 4th May 1987, pp. 2–33.Google Scholar
Waller, PJ (1997). Anthelmintic resistance. Veterinary Parasitology 72: 391–412.Google Scholar