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Prevalence of tuberculosis, brucellosis and trypanosomiasis in cattle in Tanzania: a systematic review and meta-analysis

Published online by Cambridge University Press:  18 July 2016

Silvia Alonso Open the ORCID record for Silvia Alonso [Opens in a new window] ,
Ian Dohoo ,
Johanna Lindahl ,
Cristobal Verdugo ,
Isaiah Akuku  and
Delia Grace
Silvia Alonso*
Affiliation:
Integrated sciences department, International Livestock Research Institute, Nairobi 00100, Kenya
Ian Dohoo
Affiliation:
Department of Health Management, University of PEI, Charlottetown PEI C1A 4P3, Canada
Johanna Lindahl
Affiliation:
Integrated sciences department, International Livestock Research Institute, Nairobi 00100, Kenya
Cristobal Verdugo
Affiliation:
Instituto de Medicina Preventiva Veterinaria, Universidad Austral de Chile, Valdivia, Chile
Isaiah Akuku
Affiliation:
Integrated sciences department, International Livestock Research Institute, Nairobi 00100, Kenya
Delia Grace
Affiliation:
Integrated sciences department, International Livestock Research Institute, Nairobi 00100, Kenya
*
*Corresponding author. E-mail: s.alonso@cgiar.org
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Abstract

A meta-analysis was performed to derive prevalence estimates for Brucella spp., Mycobacterium spp. and Trypanosoma spp. in cattle in Tanzania using data derived from a systematic review of zoonotic hazards in cattle production systems. Articles published before 2012 reporting prevalence and considered at least moderate in quality were included in the analysis. Results showed high heterogeneity between studies, with wide ranges in the reported prevalence: Brucella (0.3–60.8%), Mycobacterium (0.1–13.2%) and Trypanosoma (0.82–33.3%). Overall meta-analytic mean prevalence estimates were 8.2% (95% CI 6.5–10.2), 1.28% (95% CI 0.35–4.58) and 10.3% (95% CI 6.20–16.70) respectively, for Brucella spp., Mycobacterium spp. and Trypanosoma spp. Time and region were predictors of variability of Brucella spp. prevalence, while diagnostic test was a strong predictor of Mycobacterium spp. prevalence, with higher prevalence estimates given by skin tests compared with post-mortem inspection. None of the studied factors were associated with prevalence of Trypanosoma spp. The small sample sizes, range of study locations, study designs and diagnostics used, contributed to high variability among prevalence estimates. Larger and more robust prevalence studies are needed to adequately support risk assessment and management of animal and public health threats.

Keywords

Brucella spp.Mycobacterium spp.Trypanosoma spp.cattleTanzaniaprevalencemeta-analysis
Type
Review Article
Information
Animal Health Research Reviews , Volume 17 , Special Issue 1: Systematic Reviews , June 2016 , pp. 16 - 27
Copyright
Copyright © Cambridge University Press 2016 

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References

Ahmed, HA, Picozzi, K, Welburn, SC and MacLeod, ET (2013). A comparative evaluation of PCR-based methods for species-specific determination of African animal trypanosomes in Ugandan cattle. Parasites & Vectors 6: 316. [Online]. doi: 10.1186/1756-3305-6-316.Google Scholar
Akakpo, AJ, Têko-Agbo, A and Koné, P (2010). The impact of brucellosis on the economy and public health in Africa. In: Compendium of Technical Items Presented to the OIE World Assembly of Delegates or to OIE Regional Commissions, 2009. OIE (World Organisation for Animal Health), pp. 71–84.Google Scholar
Alonso, S, Lindahl, J, Roesel, K, Traore, SG, Yobouet, BA, Ndour, APN, Carron, M and Grace, D (2016). Where literature is scarce: observations and lessons learnt from four systematic reviews of zoonoses in African countries. Animal Health Research Reviews. doi: 10.1017/S1466252316000104.CrossRefGoogle ScholarPubMed
Alvarez, J, Perez, A, Bezos, J, Marqués, S, Grau, A, Saez, JL, Mínguez, O, de Juan, L and Domínguez, L (2012). Evaluation of the sensitivity and specificity of bovine tuberculosis diagnostic tests in naturally infected cattle herds using a Bayesian approach. Veterinary Microbiology 155: 38–43. [Online]. doi: 10.1016/j.vetmic.2011.07.034.Google Scholar
Ayele, WY, Neill, SD, Zinsstag, J, Weiss, MG and Pavlik, I (2004). Bovine tuberculosis: an old disease but a new threat to Africa. The International Journal of Tuberculosis and Lung Disease 8: 924–937.Google Scholar
Cleaveland, S, Shaw, DJ, Mfinanga, SG, Shirima, G, Kazwala, RR, Eblate, E and Sharp, M (2007). Mycobacterium bovis in rural Tanzania: risk factors for infection in human and cattle populations. Tuberculosis (Edinburgh, Scotland) 87: 30–43. [Online]. doi: 10.1016/j.tube.2006.03.001.Google Scholar
Connor, J (1991). The diagnosis, treatment and prevention of animal trypanosomiasis under field conditions. In: Programme for the Control of African Animal Trypanosomiasis and Related Development.Google Scholar
Corbel, MJ (2006). Brucellosis in humans and animals. WHO, FAO and OiE, WHO Press, Switzerland.Google Scholar
Cosivi, O, Grange, JM, Daborn, CJ, Raviglione, MC, Fujikura, T, Cousins, D, Robinson, RA, Huchzermeyer, HF, de Kantor, I and Meslin, FX (1998). Zoonotic tuberculosis due to Mycobacterium bovis in developing countries. Emerging Infectious Diseases 4: 59–70. [Online]. doi: 10.3201/eid0401.980108.Google Scholar
DerSimonian, R and Laird, N (1986). Meta-analysis in clinical trials. Controlled Clinical Trials 7: 177–188.Google Scholar
Durnez, L, Sadiki, H, Katakweba, A, Machang'u, RR, Kazwala, RR, Leirs, H and Portaels, F (2009). The prevalence of Mycobacterium bovis-infection and atypical mycobacterioses in cattle in and around Morogoro, Tanzania. Tropical Animal Health and Production 41: 1653–1659. [Online]. doi: 10.1007/s11250-009-9361-4.Google Scholar
Dürr, S, Müller, B, Alonso, S, Hattendorf, J, Laisse, CJM, van Helden, PD and Zinsstag, J (2013). Differences in primary sites of infection between zoonotic and human tuberculosis: results from a worldwide systematic review. PLoS Neglected Tropical Diseases 7: e2399. [Online]. doi: 10.1371/journal.pntd.0002399.Google Scholar
Gall, D and Nielsen, K (2004). Serological diagnosis of bovine brucellosis: a review of test performance and cost comparison. Revue Scientifique et Technique (International Office of Epizootics) 23: 989–1002.Google Scholar
Goossens, B, Mbwambo, H, Msangi, A, Geysen, D and Vreysen, M (2006). Trypanosomosis prevalence in cattle on Mafia Island (Tanzania). Veterinary Parasitology 139: 74–83. [Online]. doi: 10.1016/j.vetpar.2006.02.022.Google Scholar
Haidich, AB (2010). Meta-analysis in medical research. Hippokratia 14 (suppl. 1): 29–37.Google Scholar
Hyera, JMK, Kapaga, AM, Msami, HM and Schoepf, K (1996). A sero-epidemiological survey of infectious bovine rhinotracheitis/infectious pustulo-vulvovaginitis (IBR/IPV) virus and Brucella abortus in dairy cattle herds in Tanzania. Bulletin of Animal Health and Production in Africa 44: 79–81.Google Scholar
ILRI (1989). Trypanosomiasis. [Online]. [Available online at https://www.ilri.org/InfoServ/Webpub/fulldocs/ilrad89/Trypano.htm#TopOfPage] [Accessed 22 February 2016].Google Scholar
Jiwa, SFH, Kazwala, RR, Tungaraza, R, Kimera, SI and Kalaye, WJ (1996). Bovine brucellosis serum agglutination test prevalence and breed disposition according to prevalent management systems in the Lake Victoria zone of Tanzania. Preventive Veterinary Medicine 26: 341–346. [Online]. doi: 10.1016/0167-5877(95)00543-9.Google Scholar
Kaare, MT, Picozzi, K, Mlengeya, T, Fèvre, EM, Mellau, LS, Mtambo, MM, Cleaveland, S and Welburn, SC (2007). Sleeping sickness – a re-emerging disease in the Serengeti? Travel Medicine and Infectious Disease 5: 117–124. [Online]. doi: 10.1016/j.tmaid.2006.01.014.CrossRefGoogle ScholarPubMed
Karimuribo, ED, Ngowi, HA, Swai, ES and MKambarage, DM (2007). Prevalence of brucellosis in crossbred and indigenous cattle in Tanzania. Livestock Research for Rural Development 19: 148.Google Scholar
Karimuribo, ED, Morrison, LJ, Black, A, Turner, CMR, Kambarage, DM and Ballingall, KT (2011). Analysis of host genetic factors influencing African trypanosome species infection in a cohort of Tanzanian Bos indicus cattle. Veterinary Parasitology 179: 35–42. Elsevier B.V. [Online]. doi: 10.1016/j.vetpar.2011.02.001.Google Scholar
Katale, BZ, Mbugi, EV, Kendal, S, Fyumagwa, RD, Kibiki, GS, Godfrey-Faussett, P, Keyyu, JD, van Helden, P and Matee, MI (2012). Bovine tuberculosis at the human-livestock-wildlife interface: is it a public health problem in Tanzania? A review. Onderstepoort Journal of Veterinary Research 79: 1–8. [Online]. doi: http://dx.doi.org/10.4102/ojvr.v79i2.463.Google Scholar
Katale, BZ, Mbugi, EV, Karimuribo, ED, Keyyu, JD, Kendall, S, Kibiki, GS, Godfrey-Faussett, P, Michel, AL, Kazwala, RR, van Helden, P and Matee, MI (2013). Prevalence and risk factors for infection of bovine tuberculosis in indigenous cattle in the Serengeti ecosystem, Tanzania. BMC Veterinary Research 9: 267. BioMed Central. [Online]. doi: 10.1186/1746-6148-9-267.Google Scholar
Kazwala, RR, Kambarage, DM, Daborn, CJ, Nyange, J, Jiwa, SF and Sharp, JM (2001). Risk factors associated with the occurrence of bovine tuberculosis in cattle in the Southern Highlands of Tanzania. Veterinary Research Communications 25: 609–614.Google Scholar
Luckins, AG (1992). Methods for diagnosis of trypanosomiasis in livestock. Trypanosomiasis and tsetse - Africa's disease challenge. World Animal Review 70–71: 1–2.Google Scholar
Mahlau, EA (1967). Further brucellosis surveys in Tanzania. Bulletin of Epizootic Diseases of Africa. Bulletin des épizooties en Afrique 15: 373–378.Google Scholar
Malele, II (2012). Fifty years of Tsetse control in Tanzania: challenges and prospects for the future. Tanzania Journal of Health Research 13: 1–10. National Institute for Medical Research. [Online]. doi: 10.4314/thrb.v13i5.9.CrossRefGoogle Scholar
Mangen, MJ, Otte, J, Pfeiffer, DU and Chilonda, P (2002). Bovine brucellosis in Sub-Saharan Africa: estimation of sero-prevalence and impact on meat and milk offtake potential. FAO, Livestock Information and Policy Branch, Livestock Policy Discussion Paper No. 8, Rome, Italy. [Online]. [Available online at http://www.fao.org/3/a-ag274e.pdf].Google Scholar
Matope, G, Muma, JB, Toft, N, Gori, E, Lund, A, Nielsen, K and Skjerve, E (2011). Evaluation of sensitivity and specificity of RBT, c-ELISA and fluorescence polarisation assay for diagnosis of brucellosis in cattle using latent class analysis. Veterinary Immunology and Immunopathology 141: 58–63. [Online]. doi: 10.1016/j.vetimm.2011.02.005.Google Scholar
McDermott, J, Grace, D and Zinsstag, J (2013). Economics of brucellosis impact and control in low-income countries. Revue Scientifique et Technique (International Office of Epizootics) 32: 249–261.Google Scholar
Mdegela, RH, Kusiluka, LJM, Kapaga, AM, Karimuribo, ED, Turuka, FM, Bundala, A, Kivaria, F, Kabula, B, Manjurano, A, Loken, T and Kambarage, DM (2004). Prevalence and determinants of mastitis and milk-borne zoonoses in smallholder dairy farming sector in Kibaha and Morogoro districts in Eastern Tanzania. Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health 51: 123–128. Blackwell Wissenschafts-Verlag GmbH. [Online]. doi: 10.1111/j.1439-0450.2004.00735.x.Google Scholar
Mellau, LSB, Nonga, HE and Karimuribo, ED (2010). A slaughterhouse survey of lung lesions in slaughtered stocks at Arusha, Tanzania. Preventive Veterinary Medicine 97: 77–82. Elsevier B.V. [Online]. doi: 10.1016/j.prevetmed.2010.08.008.Google Scholar
Mellau, LSB, Kuya, SL and Wambura, PN (2009). Seroprevalence of brucellosis in domestic ruminants in livestock-wildlife interface: a case study of Ngorongoro Conservation Area, Arusha, Tanzania. Tanzania Veterinary Journal 26: 44–50. Tanzania Veterinary Association LA – English. [Online]. doi: 10.4314/tvj.v26i1.49234.Google Scholar
MLD (2006). National Livestock Policy. Ministry of Livestock Development. The United Republic of Tanzania. Dar es Salaam, Tanzania. [Online]. [Available online at http://www.tnrf.org/files/E-INFO_National_Livetock_Policy_Final_as_per_Cabinet_Dec-2006.pdf].Google Scholar
MLFD (2010). Livestock sector development strategy. Ministry of Livestock and Fisheries Development. The United Republic of Tanzania, Dar es Salaam, Tanzania. [Online]. [Available online at http://www.tanzania.go.tz/egov_uploads/documents/development_strategy-_Livestock_sw.pdf].Google Scholar
Mugittu, KN, Silayo, RS, Majiwa, PA, Kimbita, EK, Mutayoba, BM and Maselle, R (2001). Application of PCR and DNA probes in the characterisation of trypanosomes in the blood of cattle in farms in Morogoro, Tanzania. Veterinary Parasitology 94: 177–189.Google Scholar
Müller, B, Dürr, S, Alonso, S, Hattendorf, J, Laisse, CJM, Parsons, SDC, van Helden, PD and Zinsstag, J (2013). Zoonotic Mycobacterium bovis-induced tuberculosis in humans. Emerging Infectious Diseases 19: 899–908. [Online]. doi: 10.3201/eid1906.120543.Google Scholar
Mwakapuja, RS, Makondo, ZE, Malakalinga, J, Bryssinckx, W, Mdegela, RH, Moser, I, Kazwala, RR and Tanner, M (2013). Prevalence and significant geospatial clusters of bovine tuberculosis infection at livestock-wildlife interface ecosystem in Eastern Tanzania. Tropical Animal Health and Production 45: 1223–1230. [Online]. doi: 10.1007/s11250-013-0350-2.CrossRefGoogle ScholarPubMed
Mwambu, PM and Mayende, JSP (1973). Salivarian trypanosome infections in cattle in Ikoma, South Mara District, Tanzania. Parasitology 66: 381–385.Google Scholar
Njombe, AP, Msanga, YN, Mbwambo, NR and Temba, A (2012). Efforts to improve the dairy industry in Tanzania. In: The Smallholder Dairy Value Chain in Tanzania Stakeholder Meeting, Morogoro, Tanzania, 9 March 2012.Google Scholar
Nonga, HE and Kambarage, DM (2009). Prevalence of Bovine Trypanosomosis in Morogoro, Tanzania. Pakistan Journal of Nutrition 8: 208–213. [Online]. doi: 10.3923/pjn.2009.208.213.Google Scholar
O'Connor, AM, Anderson, KM, Goodell, CK and Sargeant, JM (2014). Conducting systematic reviews of intervention questions I: writing the review protocol, formulating the question and searching the literature. Zoonoses and Public Health 61 (suppl. 1): 28–38. [Online]. doi: 10.1111/zph.12125.Google Scholar
OIE, W. A. H. O. (2016). Manual of diagnostic tests and vaccines for terrestrial animals 2016. World Animal Health Organization (OiE). [Online]. [Available online at http://www.oie.int/international-standard-setting/terrestrial-manual/access-online/].Google Scholar
OIE, W. A. H. O. (n.d.). Animal health situation. World Animal Health Information System (WAHIS). [Online]. [Available online at http://www.oie.int/animal-health-in-the-world/the-world-animal-health-information-system/the-oie-data-system/].Google Scholar
Sargeant, JM and O'Connor, AM (2014). Conducting systematic reviews of intervention questions II: relevance screening, data extraction, assessing risk of bias, presenting the results and interpreting the findings. Zoonoses and Public Health 61 (suppl. 1): 39–51. [Online]. doi: 10.1111/zph.12124.Google Scholar
Sargeant, JM, Rajic, A, Read, S and Ohlsson, A (2006). The process of systematic review and its application in agri-food public-health. Preventive Veterinary Medicine 75: 141–151. [Online]. doi: 10.1016/j.prevetmed.2006.03.002.Google Scholar
Shirima, GM, Kazwala, RR and Kambarage, DM (2003). Prevalence of bovine tuberculosis in cattle in different farming systems in the eastern zone of Tanzania. Preventive Veterinary Medicine 57: 167–172.Google Scholar
Staak, C and Protz, D (1973). A brucellosis survey in the Masailand and Mbulu districts of Tanzania. Bulletin of Epizootic Diseases of Africa 21: 67–74.Google Scholar
Swai, ES and Kaaya, JE (2012). A parasitological survey for bovine trypanosomosis in the livestockwildlife ecozone of Northern Tanzania. Veterinary World 5: 459. [Online]. doi: 10.5455/vetworld.2012.459-464.Google Scholar
Swai, ES and Schoonman, L (2010). The use of rose bengal plate test to asses cattle exposure to Brucella infection in traditional and smallholder dairy production systems of tanga region of Tanzania. Veterinary Medicine International 2010: 837950. [Online]. doi: 10.4061/2010/837950.CrossRefGoogle ScholarPubMed
Swai, ES and Schoonman, L (2012a). Differences in prevalence of tuberculosis in indigenous and crossbred cattle under extensive and intensive management systems in Tanga region of Tanzania. Tropical Animal Health and Production 44: 459–465. [Online]. doi: 10.1007/s11250-011-9919-9.Google Scholar
Swai, E and Schoonman, L (2012b). A survey of zoonotic diseases in trade cattle slaughtered at Tanga city abattoir: a cause of public health concern. Asian Pacific Journal of Tropical Biomedicine 2: 55–60. Asian Pacific Tropical Biomedical Magazine. [Online]. doi: 10.1016/S2221-1691(11)60190-1.Google Scholar
Swai, E, Mshanga, D, Sanka, N and Marandu, N (2005). Prevalence of bovine brucellosis in smallholder dairying farming area, Moshi, Tanzania. Bulletin of Animal Health and Production in Africa 53: 97–105. [Online]. doi: 10.4314/bahpa.v53i2.32695.Google Scholar
United Nations (2015). World Population Prospects, the 2015 Revision. [Online]. [Available online at http://esa.un.org/unpd/wpp/].Google Scholar
Weinhäupl, I, Schöpf, KC, Khaschabi, D, Kapaga, AM and Msami, HM (2000). Investigations on the prevalence of bovine tuberculosis and brucellosis in dairy cattle in Dar es Salaam region and in zebu cattle in Lugoba Area, Tanzania. Tropical Animal Health and Production 32: 147–154. [Online]. doi: 10.1023/A:1005231514467.Google Scholar
WHO (2015). Trypanosomiasis, Human African (sleeping sickness). World Health Organization, Switzerland.Google Scholar