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Growth hormone release in calves selected for milk fat yield

Published online by Cambridge University Press:  02 September 2010

P. Løvendahl  and
K. Sejrsen
P. Løvendahl
Affiliation:
National Insitute of Animal Science, Research Centre Foulum, DK 8830 Tjele, Denmark
K. Sejrsen
Affiliation:
National Insitute of Animal Science, Research Centre Foulum, DK 8830 Tjele, Denmark
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Abstract

In two experiments Red Danish dairy calves of both sexes, and of two lines selected for high (H) and low (L) milk fat production (proportional difference 0·22), were tested at 4 months and again at 10 months of age for their growth hormone (GH) release following intravenous administration of either thyrotropin releasing hormone (TRH, experiment 1: 0·15 μig/kg live weight, no. = 16 H + 10 L) or arginine hydrochloride (ARG, experiment 2: 0·10 g/kg live weight, no. = 19 H + 10 L). The GH response was measured in serial blood samples for 0·5 h prior to and for 2 h following intravenous injections. The response peak, measured as the geometric mean of the 5-, 10- and 15-min samples following TRH was greater in the line selected for high yield, at 10 months (H, 42·4 μg/l; L, 20·6 μig/l; P < 0.01) but not at 4 months of age (H, 25·4 μg/l; L, 18·6 μg/l; P > 0·05). The response peak following arginine measured in the 20-, 30- and 45-min samples was smaller than the peak following TRH and did not differ between selection lines, although there was a tendency for H calves to have a larger release at 10 months of age. After puberty (10 months) male calves responded more to both secretagogues than females, while there was no difference before puberty (4 months). These results suggest that GH release may be useful as a juvenile predictor of dairy merit, but results need to be confirmed in further and larger studies.

Keywords

agedairy cattleselectionsexsomatotropin
Type
Research Article
Information
Animal Production , Volume 56 , Issue 3 , June 1993 , pp. 285 - 291
Copyright
Copyright © British Society of Animal Science 1993

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References

Anfinson, M. S., Davis, S. L., Christian, E. and Everson, D. O. 1975. Episodic secretion of growth hormone in steers and bulls: an analysis of frequency and magnitude of secretory spikes occurring in a 24 hour period. Proceedings, Western Section, American Society of Animal Science 26: 175–177.Google Scholar
Barnes, M. A., Kazmer, G. W., Akers, R. M. and Pearson, R. E. 1985. Influence of selection for milk yield on endogenous hormones and metabolites in Holstein heifers and cows. Journal of Animal Science 60: 271–284.CrossRefGoogle ScholarPubMed
Barnes, M. A., Kazmer, G. W., Pearson, R. E. and Akers, R. M. 1984. Endocrine and metabolite response after insulin, glucose or TRH in two genetically selected groups of Holstein cattle. Journal of Dairy Science 67, suppl. 1. p. 161 (abstr.).Google Scholar
Bauman, D. E., Eppard, P. J., DeGeeter, M. J. and Lanza, G. M. 1985. Responses of high producing dairy cows to long-term treatment with pituitary somatotropin and recombinant somatotropin. Journal of Dairy Science 68: 1352–1362.CrossRefGoogle ScholarPubMed
Bines, J. A., Hart, I. C. and Morant, S. V. 1983. Endocrine control of energy metabolism in the cow: diurnal variations in the hormones and metabolites in the blood plasma of beef and dairy cows. Hormone and Metabolic Research 15: 330–334.CrossRefGoogle ScholarPubMed
Bonczek, R. R., Young, C. W., Wheaton, J. E. and Miller, K. P. 1988. Response of somatotropin, insulin, prolactin, and thyroxine to selection for milk yield in Holsteins. Journal of Dairy Science 71: 2470–2479.CrossRefGoogle Scholar
Chew, B. P., Eisenman, J. R. and Tanaka, T. S. 1984. Arginine infusion stimulates prolactin, growth hormone, insulin, and subsequent lactation in pregnant dairy cows. Journal of Dairy Science 67: 2507–2518.CrossRefGoogle ScholarPubMed
Christensen, L. G., Vest, B., Jorgensen, J. and Andersen, N. 1985. Selection for high and low butterfat yield. Five hundred and eighty fifth report from the National Institute of Animal Science, Denmark.Google Scholar
Hart, I. C. 1981. Recent investigations into the physiology of beef and dairy cattle. EEC Scientific Workshop, Edinburgh. (Mimeograph.)Google Scholar
Land, R. B. 1981. Physiological criteria and genetic selection. Livestock Production Science 8: 203–213.CrossRefGoogle Scholar
Land, R. B., Carr, W. R., Hart, I. C., Osmond, T. J., Thompson, R. and Tilikaratne, N. 1983. Physiological attributes as possible selection criteria for milk production. 3. Plasma hormone concentrations and metabolite and hormonal responses to changes in energy equilibrium. Animal Production 37: 165–178.Google Scholar
Lovendahl, P., Angus, K. D. and Woolliams, J. A. 1991a. The effect of genetic selection for milk yield on the response to growth hormone secretagogues in immature cattle. Journal of Endocrinology 128: 419–424.CrossRefGoogle ScholarPubMed
Løvendahl, P., Woolliams, J. A. and Sinnett-Smith, P. A. 1991b. Response of growth hormone to various doses of growth hormone releasing factor and thyrotropin releasing hormone administered separately and in combination to dairy calves. Canadian Journal of Animal Science 71: 1045–1052.CrossRefGoogle Scholar
Lukes, A. J., Barnes, M. A. and Pearson, R. E. 1989. Response to selection for milk yield and metabolic challenges in primiparous dairy cows. Domestic Animal Endocrinology 6: 287–298.CrossRefGoogle ScholarPubMed
McAtee, J. W. and Trenkle, A. 1971. Effect of feeding, fasting and infusion of energy substrates on plasma growth hormone levels in cattle. Journal of Animal Science 33: 612–616.CrossRefGoogle ScholarPubMed
Mackenzie, D. D. S., Wilson, G. F., McCutcheon, S. N. and Peterson, S. W. 1988. Plasma metabolite and hormone concentrations as predictors of dairy merit in young Friesian bulls: effect of metabolic challenges and fasting. Animal Production 47: 1–10.Google Scholar
National Committee on Danish Cattle Husbandry. 1990. Principles of Danish cattle breeding. National Committee on Danish Cattle Husbandry, Århus.Google Scholar
Nicholas, F. W. and Smith, C. 1983. Increased rates of genetic change in dairy cattle by embryo transfer and splitting. Animal Production 36: 341–353.Google Scholar
Plouzek, C. A. and Trenkle, A. 1991. Growth hormone parameters at four ages in intact and castrated male and female cattle. Domestic Animal Endocrinology 8: 63–72.CrossRefGoogle ScholarPubMed
Sejrsen, K. and Foldager, J. 1992. Mammary growth and milk production capacity of replacement heifers in relation to diet energy concentration and plasma hormone levels. Ada Agricultarae Scandinavica. Section A: Animal Science 42: 99–105.CrossRefGoogle Scholar
Sejrsen, K., Huber, J. T. and Tucker, H. A. 1983. Influence of amount fed on hormone concentrations and their relationship to mammary growth in heifers. Journal of Dairy Science 66: 845–855.CrossRefGoogle ScholarPubMed
Tannenbaum, G. S. and Ling, N. 1984. The interrelationship of growth hormone releasing factor and somatostatin in generation of the ultradian rhythm of GH secretion. Endocrinology 115: 1952–1957.CrossRefGoogle ScholarPubMed
Woolliams, J. A. 1990. Strategies to maximise selection progress in dairy cattle. Proceedings of the fourth world congress on genetics applied to livestock production, vol. XIV, pp. 15–24.Google Scholar
Xing, G. Q., Mackenzie, D. D. S., McCutcheon, S. N., Wilson, G. F. and Flux, D. S. 1988. Plasma metabolite and hormone concentrations in Friesian calves differing in genetic potential for milkfat production. New Zealand Journal of Agricultural Research 31: 159–167.CrossRefGoogle Scholar