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Blood leptin concentrations in Japanese Black cattle

Published online by Cambridge University Press:  18 August 2016

T. Tokuda
Affiliation:
Laboratory of Animal Nutrition, Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto, 606-8502, Japan
H. Yano
Affiliation:
Laboratory of Animal Nutrition, Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto, 606-8502, Japan
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Abstract

The objective of this study was to examine the changes of serum leptin levels in heifers and steers during fattening. Seven steers and seven heifers at 14 months of age were used in the experiment. Live weight and serum leptin levels were determined at 2-month intervals. Initial live weight was greater in steers than heifers and a similar trend of growth was recorded during the experiment. As a result, live weight was higher in the steers than in the heifers during the experiment. Serum leptin concentration in both groups increased during the experiment and reached optimum level at 22 months of age and did not change thereafter. The increase in serum leptin level was more marked in heifers and leptin level was higher (P < 0·05) in heifers than steers between 18 and 26 months of age. The results suggest that serum leptin level increases during fattening in cattle and the trend is possibly affected by gender.

Type
Growth, development and meat science
Copyright
Copyright © British Society of Animal Science 2001

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References

Campfield, L. A., Smith, F. J. and Burn, P. 1996. The OB protein (leptin) pathway – a link between adipose tissue mass and central neural networks. Hormone and Metabolic Research 28: 619632.CrossRefGoogle ScholarPubMed
Campfield, L. A., Smith, F. J., Guisez, Y., Devos, R. and Burn, P. 1995. Recombinant mouse ob protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269: 546549.Google Scholar
Caro, J. F., Sinha, M. K., Kolaczynski, J. W., Zhang, P. L. and Considine, R. V. 1996. Leptin: the tale of an obesity gene. Diabetes 45: 14551462.Google Scholar
Considine, R. V., Sinha, M. K., Heiman, M. L., Kriauciunas, A., Stephens, T. W., Nyce, M. R., Ohannesian, J. P., Marco, C. C., McKee, L. J., Bauer, T. L. and Caro, J. F. 1996. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. The New England Journal of Medicine 334: 292295.Google Scholar
Coppack, S. W., Pinkney, J. H. and Mohamed-Ali, V. 1998. Leptin production in human adipose tissue. Proceedings of the Nutrition Society 57: 461470.CrossRefGoogle ScholarPubMed
Dulphy, J. P., Remond, B. and Theriez, M. 1979. Ingestive behaviour and related activities in ruminants. In Digestive physiology and metabolism in ruminants (ed. Ruckebusch, Y. and Thivend, P.), pp. 103122. MTP Press Limited, England.Google Scholar
Halaas, J. L., Gajiwala, K. S., Maffei, M., Cohen, S. L., Chait, B. T., Rabinowitz, D., Lallone, R. L., Burley, S. K. and Friedman, J. M. 1995. Weight-reducing effects of the plasma-protein encoded by the obese gene. Science 269: 543546.CrossRefGoogle ScholarPubMed
Havel, P. J., Kasim-Karakas, S., Dubuc, G. R., Mueller, W. and Phinney, S.D. 1996. Gender differences in plasma leptin concentrations. Nature Medicine 2: 949950.Google Scholar
Hoshi, S. and Yamauchi, M. 1990. Kachikurinsyohansyokugaku, pp. 6061. Asakura-shoten Co. Ltd, Tokyo.Google Scholar
Hoshino, T. 1987. [An aspect of fat accumulation.] In Shin Nyugyu no Kagaku (ed. Tsuda, T. and Shibata, F.), pp. 322326. Nousan Gyoson Bunka Kyoukai, Tokyo.Google Scholar
Hosoda, K., Masuzaki, H., Ogawa, Y., Miyawaki, T., Hiraoka, J., Hanaoka, I., Yasuno, A., Nomura, T., Fujisawa, Y., Yoshimasa, Y., Nishi, S., Yamori, Y. and Nakao, K. 1996. Development of radioimmunoassay for human leptin. Biochemical and Biophysical Research Communications 221: 234239.CrossRefGoogle ScholarPubMed
Houseknecht, K. L., Baile, C. A., Matteri, R. L. and Spurlock, M. E. 1998. The biology of leptin: a review. Journal of Animal Science 76: 14051420.Google Scholar
Jago, J. G., Cox, N. R., Bass, J. J. and Matthews, L. R. 1997. The effect of prepubertal immunization against gonadotropin-releasing hormone on the development of sexual and social behavior of bulls. Journal of Animal Science 75: 26092619.Google Scholar
Jenkins, A. B., Markovic, T. P., Fleury, A. and Campbell, L. V. 1997. Carbohydrate intake and short-term regulation of leptin in humans. Diabetrogia 40: 348351.Google Scholar
Kameoka, K. 1966. [Digestion of feed in the rumen. ] In Nyugyu no Kagaku (ed. Umezu, M.), pp. 241251. Nousan Gyoson Bunka Kyoukai, Tokyo.Google Scholar
Landt, M., Gingerich, R. L., Havel, P. J., Mueller, W. M., Schoner, B. J., Hale, E. and Heiman, M. L. 1998. Radioimmunoassay of rat leptin: sexual dimorphism reversed from humans. Clinical Chemistry 44: 565570.Google Scholar
Luukkaa, V., Pesonen, U., Huhtaniemi, I., Lehtonen, A., Tilvis, R., Tuomilehto, J., Koulu, M. and Huupponen, R. 1998. Inverse correlation between serum testosterone and leptin in men. Journal of Clinical Endocrinology and Metabolism 83: 32433246.Google ScholarPubMed
Mantzoros, C. S., Flier, J. S. and Rogol, A. D. 1997. A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty. Journal of Clinical Endocrinology and Metabolism 82: 10661070.Google Scholar
Minton, J. E., Bindel, D. J., Drouillard, J. S., Titgemeyer, E. C., Grieger, D. M. and Hill, C. M. 1998. Serum leptin is associated with carcass traits in finishing cattle. Journal of Animal Science 76: (suppl. ) 231.Google Scholar
Murakami, T., Iida, M. and Shima, K. 1995. Dexamethasone regulates obese expression in isolated rat adipocytes. Biophysiology Research Communications 214: 12601267.Google Scholar
Ostlund Jr, R. E., Wang, J. W., Klein, S. and Gingerrich, R. 1996. Relation between plasma leptin concentration and body fat, gender, diet, age, and metabolic covariates. Journal of Clinical Endocrinology and Metabolism 81: 39093913.Google ScholarPubMed
Pelleymounter, M. A., Cullen, M. J., Baker, M. B., Hecht, R., Winters, D., Soone, T. and Collins, F. 1995. Effects of the obese gene-product on body-weight regulation in ob/ob mice. Science 269: 540543.Google Scholar
Shimize, H., Shimomura, Y., Nakanishi, Y., Futawatari, T., Ohtani, K., Sato, N. and Mori, M. 1997. Estrogen increases in vivo leptin production in rats and human subjects. Journal of Endocrinology 154: 285292.Google Scholar
Sinha, M. K., Sturis, J., Ohannesian, J., Magosin, S., Stephens, T., Heiman, M. L., Polonsky, K. S. and Caro, J. F. 1996. Ultradian oscillations of leptin secretion in humans. Biochemical and Biophysical Research Communications 228: 733738.Google Scholar
Statistical Analysis Systems Institute. 1985. SAS user’s guide: statistics, version 5 edition. SAS Institute Inc., Cary, NC. Google Scholar
Takahashi, E., Matsui, T., Wakamatsu, S., Yuri, N., Shiojiri, Y., Matsuyama, R., Murakami, H., Tanaka, S., Torii, S. and Yano, H. 1999. [Serum vitamin C concentration in fattening and fattened beef cattle. ] Animal Science Journal 70: J114J118.Google Scholar
Tokuda, T., Matsui, T., Ito, J., Torii, S. and Yano, H. 2000. The changes in body weight and plasma metabolite levels during leptin injection are caused by the reduction of food intake in sheep. Animal Science 70: 343348.Google Scholar
Tokuda, T., Matsui, T. and Yano, H. 1999. Leptin concentrations in the blood of ruminants. Proceedings of the ninth international symposium on ruminant physiology, Pretoria, South Africa, pp. 211212.Google Scholar
Yoneda, N., Saito, S., Kimura, M., Yamada, M., Iida, M., Murakami, T., Irahara, M., Sima, K. and Aono, T. 1998. The influence of ovariectomy on ob gene expression in rats. Hormone and Metabolic Research 30: 263265.CrossRefGoogle ScholarPubMed
Zhang, Y. Y., Proenca, R., Maffei, M., Barone, M., Leopold, L. and Friedman, J. M. 1994. Positional cloning of the mouse obese gene and its human homolog. Nature 372: 425432.Google Scholar