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Genetic and phenotypic relationships among faecal egg count, anti-nematode antibody level and live weight in Angus cattle

Published online by Cambridge University Press:  18 August 2016

C.A. Morris ,
R.S. Green ,
N.G. Cullen  and
S.M. Hickey
C.A. Morris*
Affiliation:
AgResearch, Ruakura Research Centre, Private Bag 3123, Hamilton, New Zealand
R.S. Green
Affiliation:
AgResearch, Wallaceville Animal Research Centre, PO Box 40-063, Upper Hutt, New Zealand
N.G. Cullen
Affiliation:
AgResearch, Ruakura Research Centre, Private Bag 3123, Hamilton, New Zealand
S.M. Hickey
Affiliation:
AgResearch, Ruakura Research Centre, Private Bag 3123, Hamilton, New Zealand
*
†E-mail: chris.morris@agresearch.co.nz
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Abstract

Genetic variation in host resistance to nematode infection was studied in two calf crops of Angus cattle under natural pasture challenge conditions in New Zealand, using faecal egg count (FEC) as a marker trait. Genetic and phenotypic correlations of FEC with anti-nematode antibody (Ab) level and live weights were also estimated. Ab to the third larval stages of Cooperia curticei (Cc), Cooperia oncophora (Co), Ostertagia ostertagi (Oo) and Trichostrongylus colubriformis (Tc) were assayed, along with Ab to the adult stages of Co and Oo. Calves were born in the late winter/early spring of 1995 and 1996 over a 7-week period each year; they were weaned at an average of 4 months of age, and faecal samples for FEC were taken at 10 months of age (1995 crop) and at 7 months of age (1996 crop). Blood samples for Ab were taken from both calf crops at intervals between 4 and 20 months of age, and later in peri-partum heifers and cows (23 to 25, and 36 to 37 months of age). For the two calf crops combined, there were 370 animals by 24 sires. Additional blood samples were taken on related animals from the 1993 and 1994 calf crops (218 extra animals, 19 different extra sires). The heritability of loge (FEC + 100) was 0•32 (s.e. 0•16), and heritabilities of loge Ab between 4 and 9 months of age averaged 0•30, between 11 and 20 months of age 0•22, and peri-partum 0•30. Between-animal repeatabilities of Ab levels from samples taken between 4 and 9 months of age averaged 0•40, between 11 and 20 months 0•48, and peri-partum 0•35. Genetic and phenotypic correlations among loge Abs for various nematode species (in hosts aged 4 to 9 months) averaged 0•82 and 0•61, respectively. The corresponding genetic and phenotypic correlations between loge Ab and loge(FEC + 100) averaged –0•48 and –0•07, respectively, whilst those between loge Ab and yearling weight averaged 0•29 and 0•13, respectively. It was concluded that direct selection to reduce FEC should be feasible if required, but index selection combining increased live weight and reduced FEC would often be preferable; anti-nematode Ab levels were repeatable, and FEC and Ab levels were negatively associated genetically.

Keywords

cattledisease resistancegeneticsnematodaparasites.
Type
Breeding and genetics
Information
Animal Science , Volume 76 , Issue 2 , April 2003 , pp. 167 - 174
Copyright
Copyright © British Society of Animal Science 2003

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References

Barlow, R. and Piper, L. R. 1985. Genetic analyses of nematode egg counts in Hereford and crossbred Hereford cattle in the subtropics of New South Wales. Livestock Production Science 12: 79–84.CrossRefGoogle Scholar
Bisset, S. A. 1994. Helminth parasites of economic importance in cattle in New Zealand. New Zealand Journal of Zoology 21: 9–22.CrossRefGoogle Scholar
Bisset, S. A., Morris, C. A., McEwan, J. C. and Vlassoff, A. 2001. Breeding sheep in New Zealand that are less reliant on anthelmintics to maintain health and productivity. New Zealand Veterinary Journal 49: 236–246.CrossRefGoogle ScholarPubMed
Bisset, S. A., Vlassoff, A., Douch, P. G. C., Jonas, W. E., West, C. J. and Green, R. S. 1996. Nematode burdens and immunological responses following natural challenge in Romney lambs selectively bred for low or high faecal worm egg count. Veterinary Parasitology 61: 249–263.CrossRefGoogle ScholarPubMed
Burrow, H. M. 2001. Variances and covariances between productive and adaptive traits and temperament in a composite breed of tropical beef cattle. Livestock Production Science 70: 213–233.CrossRefGoogle Scholar
Douch, P. G. C., Green, R. S., Morris, C. A., Bisset, S. A., Vlassoff, A., Baker, R. L., Watson, T. G., Hurford, A. P. and Wheeler, M. 1995a. Genetic and phenotypic relationships among anti-Trichostrongylus colubriformis antibody level, faecal egg count and body weight traits in grazing Romney sheep. Livestock Production Science 41: 121–132.CrossRefGoogle Scholar
Douch, P. G. C., Green, R. S., Morris, C. A. and Hickey, S. M. 1995b. Genetic factors affecting antibody responses to four species of nematode parasite in Romney ewe lambs. International Journal for Parasitology 25: 823–828.CrossRefGoogle ScholarPubMed
Douch, P. G. C., Green, R. S. and Risdon, P. L. 1994. Antibody responses of sheep to challenge with Trichostrongylus colubriformis and the effect of dexamethasone treatment. International Journal for Parasitology 24: 921–928.CrossRefGoogle ScholarPubMed
Esdale, C. R., Leutton, R. D., O’Rourke, P. K. and Rudder, T.H. 1986. The effects of sire selection for helminth egg counts on progeny helminth egg counts and live weight. Proceedings of the Australian Society of Animal Production 16: 199–202.Google Scholar
Familton, A. S., Mason, P. and Coles, G. C. 2001. Anthelmintic-resistant Cooperia species in cattle. Veterinary Record 149: 719–720.Google ScholarPubMed
Gasbarre, L. C., Leighton, E. A. and Davies, C. J. 1993a. Influence of host genetics upon antibody responses against gastrointestinal nematode infections in cattle. Veterinary Parasitology 46: 1-4 and 81-91.CrossRefGoogle ScholarPubMed
Gasbarre, L. C. and Miller, J. E. 2000. Genetics of helminth resistance. In Breeding for disease resistance in farm animals (ed. Axford, R.F.E., Bishop, S.C., Nicholas, F.W. and Owen, J.B.), pp. 129–152. CABI Publishing, Wallingford.Google Scholar
Gasbarre, L. C., Nansen, P., Monrad, J., Gronveld, J., Steffan, P. and Henriksen, S. A. 1993b. Serum anti-trichostrongyle antibody responses of first and second season grazing calves. Research in Veterinary Science 54: 340–344.CrossRefGoogle ScholarPubMed
Gilmour, A. R. 1997. ASREML for testing fixed effects and estimating multiple trait variance components. Proceedings of the Association for the Advancement of Animal Breeding and Genetics 12: 386–390.Google Scholar
Green, R. S., Morris, C. A., Douch, P. G. C., Wheeler, M., West, C. J. and Hickey, S. M. 1999. Means and heritabilities of concentrations of antibody to Trichostrongylus colubriformis and other nematode parasites in lambs from three to seventeen months of age. Livestock Production Science 58: 129–135.CrossRefGoogle Scholar
Kloosterman, A., Albers, G. A. A. and Brink, R. van den. 1978. Genetic variation among calves in resistance to nematode parasites. Veterinary Parasitology 4: 353–368.CrossRefGoogle Scholar
Kloosterman, A., Parmentier, H. K. and Ploeger, H. W. 1992. Breeding cattle and sheep for resistance to gastrointestinal nematodes. Parasitology Today 8: 330–335.CrossRefGoogle ScholarPubMed
Leighton, E. A., Murrell, K. D. and Gasbarre, L. C. 1989. Evidence for genetic control of nematode egg-shedding rates in calves. Journal of Parasitology 75: 498–504.CrossRefGoogle ScholarPubMed
McKenna, P.B. 1996. Anthelmintic resistance in cattle nematodes in New Zealand: is it increasing? New Zealand Veterinary Journal 44: 76.Google Scholar
Morris, C. A., Bisset, S. A., Vlassoff, A., West, C. J. and Wheeler, M. 1998. Faecal nematode egg counts in lactating ewes from Romney flocks selectively bred for divergence in lamb faecal egg count. Animal Science 67: 283–288.CrossRefGoogle Scholar
Morris, C. A., Cullen, N. G., Green, R. S. and Hickey, S. M. 2002. Sire effects on antibodies to nematode parasites in grazing dairy cows. New Zealand Journal of Agricultural Research 45: 179–185.CrossRefGoogle Scholar
Morris, C. A., Jones, K. R., Wilson, J. A. and Watson, T. G. 1992. Comparison of the Brahman and Friesian breeds as sires for beef production in New Zealand. New Zealand Journal of Agricultural Research 35: 277–286.CrossRefGoogle Scholar
Morris, C. A., Vlassoff, A., Bisset, S. A., Baker, R. L., Watson, T. G., West, C. J. and Wheeler, M. 2000a. Continued selection of Romney sheep for resistance or susceptibility to nematode infection: estimates of direct and correlated responses. Animal Science 70: 17–27.CrossRefGoogle Scholar
Morris, C. A., Watson, T. G., Bisset, S. A., Vlassoff, A. and Douch, P. G. C. 1995. Breeding sheep in New Zealand for resistance or resilience to nematode parasites. In Breeding for resistance to infectious diseases in small ruminants (ed. G. D. Gray, R. R. Woolaston and Eaton, B. T.), pp. 77–98. Australian Centre for International Agricultural Research.Google Scholar
Morris, C. A. and Wilson, J. A. 1997. Progress with selection to change age at puberty and reproductive rate in Angus cattle. Proceedings of the New Zealand Society of Animal Production 57: 9–11.Google Scholar
Morris, C. A., Wilson, J. A., Bennett, G. L., Cullen, N. G., Hickey, S. M. and Hunter, J. C. 2000b. Genetic parameters for growth, puberty, and beef cow reproductive traits in a puberty selection experiment. New Zealand Journal of Agricultural Research 43: 83–91.CrossRefGoogle Scholar
Seifert, G. W. 1977. The genetics of helminth resistance in cattle. Proceedings of the third international congress of the Society for the Advancement of Breeding Researches in Asia and Oceania, Canberra, Australia, February 1977, section 7, pp. 4–8.Google Scholar
Statistical Analysis Systems Institute. 1995. JMP version 3. SAS Institute, Cary, NC.Google Scholar
Vermunt, J. J., West, D. M. and Pomroy, W. E. 1996. Inefficacy of moxidectin and doramectin against ivermectin-resistant Cooperia spp. of cattle in New Zealand. New Zealand Veterinary Journal 44: 188–193.CrossRefGoogle ScholarPubMed
Woolaston, R. R. and Piper, L. R. 1996. Selection of Merino sheep for resistance to Haemonchus contortus: genetic variation. Animal Science 62: 451–460.CrossRefGoogle Scholar