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Genetic variability in resistance to gastro-intestinal strongyles during early lactation in Creole goats

Published online by Cambridge University Press:  09 March 2007

N. Mandonnet ,
A. Menendez-Buxadera ,
R. Arquet ,
M. Mahieu ,
M. Bachand  and
G. Aumont
N. Mandonnet*
Affiliation:
Institut National de Recherche Agronomique (INRA), Unité de Recherches Zootechniques, Domaine Duclos, 97170 Petit-Bourg, French West Indies
A. Menendez-Buxadera
Affiliation:
Institut National de Recherche Agronomique (INRA), Unité de Recherches Zootechniques, Domaine Duclos, 97170 Petit-Bourg, French West Indies
R. Arquet
Affiliation:
INRA, Domaine expérimental de Gardel, 91120 Le Moule, French West Indies
M. Mahieu
Affiliation:
Institut National de Recherche Agronomique (INRA), Unité de Recherches Zootechniques, Domaine Duclos, 97170 Petit-Bourg, French West Indies
M. Bachand
Affiliation:
Institut National de Recherche Agronomique (INRA), Unité de Recherches Zootechniques, Domaine Duclos, 97170 Petit-Bourg, French West Indies
G. Aumont
Affiliation:
Institut National de Recherche Agronomique (INRA), Unité de Recherches Zootechniques, Domaine Duclos, 97170 Petit-Bourg, French West Indies
*
†E-mail: Nathalie.Mandonnet@antilles.inra.fr
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Abstract

The study was undertaken in a Creole goat flock at INRA-Gardel in Guadeloupe, to evaluate the opportunity to use artificial selection as a means of controlling gastro-intestinal infection during early lactation. The flock grazed all year on Digitaria decumbens pastures. Faecal and blood samples were taken from kids at 11 months of age and from does at kidding before drenching (week 0) and at weeks 4 and 6 after kidding. Faecal egg counts (FEC) were estimated using a modified McMaster method. Blood samples were used to determine packed cell volume (PCV) and eosinophil concentrations (EOS) values. Haemonchus contortus, Trichostrongylus colubriformis and Oesophagostomum columbianum were the main strongyle species identified in faecal cultures. The data came from 1092 litters obtained from 688 does sired by 142 bucks and 413 dams. Variance and covariance components for genetic and residual effects were estimated with multivariate animal models using the restricted maximum likelihood VCE package. Repeatability and overall heritability for FEC during the post-partum period were 0·17 and 0·10±0·02. The genetic correlations between FEC and PCV were −0·56±0·11 at 4 weeks after kidding and −0·79±0·13 at 6 weeks after kidding. The genetic correlations between FEC and EOS were 0·37±0·15 at 4 weeks after kidding and 0·68±0·17 at 6 weeks after kidding. Hence, does that contributed least to pasture contamination during the postpartum period also had low EOS and high PCV breeding values. The genetic correlations between FEC measured at 11 months of age and FEC during periparturient period ranged from 0·57±0·12 to 0·76±0·16. Therefore, breeding goats for increased resistance during the post-weaning period will lead to a less marked and less persistent rise in doe FEC during early lactation. The epidemiological implications of this selection have to be quantified in terms of lower pasture contamination, lower kid parasitism, and higher milk production of does.

Keywords

genetic parametersgoatsNematodaresistance
Type
Research Article
Information
Animal Science , Volume 82 , Issue 3 , June 2006 , pp. 283 - 287
Copyright
Copyright © British Society of Animal Science 2006

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References

Aumont, G., Pouillot, R. and Mandonnet, N. 1997. Le dénombrement des éléments parasitaires: un outil pour l'étude de la résistance génétique aux endo-parasites chez les petits ruminants. Proceedings of final workshop of ATP CIRAD-MIPA 72/94, Guadeloupe, FranceGoogle Scholar
Aumont, G., Mandonnet, N., Mahieu, M., Arquet, R., Varo, H. and Hostache, G. 1998. Peri parturient rise in small ruminants of the French West Indies. Proceedings of the second international conference on novel approaches to the control of helminth parasites of livestock, Baton Rouge, Louisiana, 22–26 March, 1998 , p.114Google Scholar
Baker, R. L., Audho, J. O., Aduda, E. O. and Thorpe, W. 2001. Genetic resistance to gastro-intestinal nematode parasites in Galla and Small East African goats in the sub-humid tropics. Animal Science 73: 61–70.CrossRefGoogle Scholar
Baker, R. L., Mwamachi, D. M., Audho, J. O., Aduda, E. O. and Thorpe, W. 1998. Resistance of Galla and Small East African goats in the sub-humid tropics to gastrointestinal nematode infections and the peri-parturient rise in faecal egg counts. Veterinary Parasitology 79: 53–64.CrossRefGoogle ScholarPubMed
Barger, I. A. 1993. Influence of sex and reproductive status on susceptibility of ruminants to nematode parasitism. International Journal for Parasitology 23: 463–469.CrossRefGoogle ScholarPubMed
Bishop, S. C. and Stear, M. J. 1999. Genetic and epidemiological relationships between productivity and disease resistance: gastro-intestinal parasite infection in growing lambs. Animal Science 69: 515–524.CrossRefGoogle Scholar
Bishop, S. C. and Stear, M. J. 2001. Inheritance of faecal egg counts during early lactation in Scottish Blackface ewes facing mixed, natural nematode infections. Animal Science 73: 389–395.CrossRefGoogle Scholar
Chauhan, K. K., Rout, P. K., Singh, P. K., Mandal, A., Singh, H. N., Roy, R. and Singh, S. K. 2003. Susceptibility to natural gastro-intestinal nematode infection in different physiological stages in Jamunapari and Barbari goats in the semi-arid tropics. Small Ruminant Research 50: 219–223.CrossRefGoogle Scholar
Chemineau, P. 1987. Possibilities for using bucks to stimulate ovarian and oestrus cycles in anovulatory goats–a review. Livestock Production Science 17: 135–147.CrossRefGoogle Scholar
Courtney, C. H., Gessner, R., Sholz, S. R. and Loggins, P. E. 1986. The peri-parturient rise in fecal egg counts in the three strains of the Florida Native ewes and its value in predicting resistance of the lambs to Haemonchus contortus. International Journal for Parasitology 16: 185–189.CrossRefGoogle Scholar
Davies, G., Stear, M. J. and Bishop, S. C. 2005. Genetic relationships between indicator traits and nematode parasite infection levels in 6-month-old lambs. Animal Science 80: 143–150.CrossRefGoogle Scholar
Dawkins, H. J. S., Windon, R. G. and Eagleson, G. K. 1989. Eosinophil responses in sheep selected for high and low responsiveness to Trichostrongylus colubriformis. International Journal for Parasitology 19: 199–205.CrossRefGoogle ScholarPubMed
Eady, S. J., Woolaston, R. R. and Barger, I. A. 2003. Comparison of genetic and nongenetic strategies for control of gastrointestinal nematodes of sheep. Livestock Production Science 81: 11–23.CrossRefGoogle Scholar
Gruner, L., Cortet, J., Sauve, C., Limouzin, C. and Brunel, J. C. 2002. Evolution of nematode community in grazing sheep selected for resistance and susceptibility to Teladorsagia circumcincta and Trichostrongylus colubriformis: a 4-year experiment. Veterinary Parasitology 109: 277–291.CrossRefGoogle ScholarPubMed
Kovac, M., Groeneveld, E. and Garcia-Cortés, L. A. 2002. VCE-5, a package for the estimation of dispersion parameters. Proceedings of the seventh world congress on genetics applied to livestock production, Montpellier, France, vol. 28, p. 6.Google Scholar
Mandonnet, N., Aumont, G., Fleury, J., Arquet, R., Varo, H., Gruner, L., Bouix, J. and Vu Tien Khang, J. 2001. Assessment of genetic variability of resistance to gastrointestinal nematode parasites in Creole goats in the humid tropics. Journal of Animal Science 79: 1706–1712.CrossRefGoogle ScholarPubMed
Mandonnet, N., Bachand, M., Mahieu, M., Arquet, R., Baudron, F., Abinne-Molza, L., Varo, H. and Aumont, G. 2005. Impact on productivity of peri-parturient rise in fecal egg counts in Creole goats in the humid tropics. Veterinary Parasitology 134: 249–259.CrossRefGoogle ScholarPubMed
Morris, C. A., Bisset, S. A., Vlassoff, A., West, C. J. and Wheeler, M. 1998. Faecal nematode egg counts in lactating ewes from Romney flocks selectively bred for divergence in lamb faecal egg count. Animal Science 67: 283–288.CrossRefGoogle Scholar
Morris, C. A., Wheeler, M., Hosking, B. C., Watson, T. G., Hurford, A. P., Foote, B. J. and Foote, J. F. 1997. Genetic parameters for milk yield and faecal nematode egg count in Saanen does. New Zealand Journal of Agricultural Research 40: 523–528.CrossRefGoogle Scholar
O'Sullivan, B. M. and Donald, A. D. 1973. Responses to infection with Haemonchus contortus and Trichostrongylus colubriformis in ewes of different reproductive status. International Journal for Parasitology 3: 521–530.CrossRefGoogle ScholarPubMed
Over, H. J., Jansen, J. and Von Olm, P. W. 1992. Distribution and impact of helminth diseases of livestock in developing countries. Food and Agriculture Organisation of the United Nations Animal Production and Health paper 96.Google Scholar
Pépin, L. 1994. Recherche de polymorphisme génétique chez les caprins: Application à l'étude de la diversité des populations, au contrôle de filiation et à la résistance à la Cowdriose. Thèse de l'Université Paris XIGoogle Scholar
Vanimisetti, H. B., Andrew, S. L., Zajac, A. M. and Notter, D. R. 2004. Inheritance of fecal egg count and packed cell volume and their relationship with production traits in sheep infected with Haemonchus contortus. Journal of Animal Science 82: 1602–1611.CrossRefGoogle ScholarPubMed
Waller, P. J. 1999. International approaches to the concept of integrated control of nematode parasites of livestock. International Journal for Parasitology 29: 155–164.CrossRefGoogle Scholar
Watson, T. G., Hosking, B. C., Morris, C. A. and Hurford, A. P. 1995. Faecal nematode egg counts and haematology in Perendale ewes near lambing. Proceedings of the New Zealand Society of Animal Production 55: 204.Google Scholar
Woolaston, R. R. 1992. Selection of Merino sheep for increased and decreased resistance to Haemonchus contortus: peri-parturient effects on faecal egg counts. International Journal for Parasitology 22: 947–953.CrossRefGoogle ScholarPubMed