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A note on the concentrations of steroidal residues in tissues of mature female sheep implanted with trenbolone acetate

Published online by Cambridge University Press:  02 September 2010

L. J. MacVinish  and
H. Galbraith
L. J. MacVinish
Affiliation:
University of Aberdeen, School of Agriculture, 581 King Street, Aberdeen AB9 1UD
H. Galbraith
Affiliation:
University of Aberdeen, School of Agriculture, 581 King Street, Aberdeen AB9 1UD
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Abstract

Thirty-two Blackface female mature sheep weighing 45 kg on average were blocked by weight and randomly allocated 60 days before slaughter to be untreated controls (C) or subcutaneously implanted with 20 (TA1), 40 (TA2) or 60 (TA3) mg trenbolone acetate (TBA). Samples of blood were collected throughout the study and post-mortem samples of selected body tissues were analysed residues.

Concentrations in blood of 17β-hydroxy-trenbolone (TBOH) peaked within 1 to 2 weeks of implantation and declined thereafter. Concentrations in blood of oestradiol-17β (OE) were elevated and generally increased with increasing dose levels of TBA. The highest concentrations of solvent extractable residues (TBOH for group TA3) ranged from 613 ng/kg in kidney to 130 ng/kg for rib muscle. Trenbolone-17β- glucuronide was detected in liver and kidney at maximum concentrations of 157 ng/kg and 94 ng/kg respectively. Implantation with TBA had no effect on concentrations of OE in any of the post-mortem tissues examined.

Keywords

meat productionoestradiolsheeptrenbolone
Type
Research Article
Information
Animal Production , Volume 56 , Issue 2 , April 1993 , pp. 277 - 280
Copyright
Copyright © British Society of Animal Science 1993

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