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Taql growth hormone gene polymorphism and milk production traits in Holstein-Friesian cattle

Published online by Cambridge University Press:  02 September 2010

M. Falaki ,
M. Sneyers ,
A. Prandi ,
S. Massart ,
C. Corradini ,
A. Formigoni ,
A. Burny ,
D. Portetelle  and
R. Renaville
M. Falaki
Affiliation:
Molecular Biology and Animal Physiology Department, Faculty of Agronomy, 13 Avenue Maréchal Juin, B-5030 Gembloux, Belgium
M. Sneyers
Affiliation:
Molecular Biology and Animal Physiology Department, Faculty of Agronomy, 13 Avenue Maréchal Juin, B-5030 Gembloux, Belgium Microbiology Department, Faculty of Agronomy, 6 Avenue Maréchal Juin, B-5030 Gembloux, Belgium
A. Prandi
Affiliation:
Dipartimento di Scienze degli Alimenti, Sezione di Fisiologia Veterinaria e Nutrizione, Università degli Studi di Udine, 33010 Pagnacco (Udine), Italy
S. Massart
Affiliation:
Molecular Biology and Animal Physiology Department, Faculty of Agronomy, 13 Avenue Maréchal Juin, B-5030 Gembloux, Belgium Microbiology Department, Faculty of Agronomy, 6 Avenue Maréchal Juin, B-5030 Gembloux, Belgium
C. Corradini
Affiliation:
Dipartimento di Scienze degli Alimenti, Sezione di Fisiologia Veterinaria e Nutrizione, Università degli Studi di Udine, 33010 Pagnacco (Udine), Italy
A. Formigoni
Affiliation:
Facultà di Medicina Veterinaria, Istituto di Zootecnia e Nutrizione Animate, Università degli Studi di Bologna, 40064 Ozzano Emilia (Bologna), Italy
A. Burny
Affiliation:
Molecular Biology and Animal Physiology Department, Faculty of Agronomy, 13 Avenue Maréchal Juin, B-5030 Gembloux, Belgium
D. Portetelle
Affiliation:
Microbiology Department, Faculty of Agronomy, 6 Avenue Maréchal Juin, B-5030 Gembloux, Belgium
R. Renaville
Affiliation:
Molecular Biology and Animal Physiology Department, Faculty of Agronomy, 13 Avenue Maréchal Juin, B-5030 Gembloux, Belgium
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Abstract

The positive effect of administration of growth hormone (GH) on milk production and its presence in selected dairy cattle lines of higher GH concentrations prompted an examination of the presence of restriction fragment length polymorphism (RFLP) in the growth hormone gene using the enzyme Taq/ and to investigate associations between this polymorphism and milk production traits. Blood was sampled from 251 Italian Holstein-Friesian cows. Three fragment bands, arbitrarily denoted A, B and E, of 6·2, 5·2 and 1·9 kilobase (kb), respectively, were observed. Their combinations exhibited six patterns, AA, AB, ABE, AE, BB and BE with frequencies of 64·5, 24·3, 2·4, 6·8, 1·4 and 0·4%, respectively. The statistical analysis was performed using linear mixed animal models. The results indicated an effect of the GHgene polymorphic Taq/restriction fragment on 305-day productions of milk, fat and protein; the low frequency pattern AE showed productions inferior to those for AA or AB patterns. Effect estimates of AA, AB and AE were, respectively, 200 (s.e. 215), 218 (s.e. 267) and -910 (s.e. 380) kg for milk production, 7·75 (s.e. 7·98), 16·10 (s.e. 9·79) and -22·14 (s.e. 14·42) kg for fat production, and 6·78 (s.e. 6·21), 8·57 (s.e. 7·58) and -20·74 (s.e. 11·14) kg for protein production. The average substitution effect estimates of E were -891 (s.e. 278), -26·56 (s.e. 10·16) and -24·50 (s.e. 9·43) kg for milk, fat and protein yields, respectively. In conclusion, these results suggest that the E fragment deserves further designed and specific study.

Keywords

dairy cattlemilk productionrestriction fragment length polymorphismsomatotropin
Type
Research Article
Information
Animal Science , Volume 63 , Issue 2 , October 1996 , pp. 175 - 181
Copyright
Copyright © British Society of Animal Science 1996

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