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Selective breeding of primates for use in research: consequences and challenges

Published online by Cambridge University Press:  01 January 2023

P Honess ,
M-A Stanley-Griffiths ,
S Narainapoulle ,
S Naiken  and
T Andrianjazalahatra
P Honess*
Affiliation:
Oxford University Veterinary Services, Parks Road, Oxford OX1 3PT, UK School of Veterinary Medicine and Science, Sutton Bonington, University of Nottingham, UK
M-A Stanley-Griffiths
Affiliation:
Bioculture (Mauritius) Ltd, Riviere des Anguilles, Mauritius
S Narainapoulle
Affiliation:
Bioculture (Mauritius) Ltd, Riviere des Anguilles, Mauritius
S Naiken
Affiliation:
Bioculture (Mauritius) Ltd, Riviere des Anguilles, Mauritius
T Andrianjazalahatra
Affiliation:
Bioculture (Mauritius) Ltd, Riviere des Anguilles, Mauritius
*
* Contact for correspondence and requests for reprints: paul.honess@vet.ox.ac.uk
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Abstract

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Primates are bred in captivity for a number of purposes, from zoo-based captive breeding programmes for conservation to breeding for biomedical research. In each case, breeding animals that are fit for purpose, either as viable candidates for reintroduction or as valid research models, has presented challenges and resulted in steep learning curves. The breeding of animals for biomedical research has become increasingly focused on the production of animals that are less stressed by captive (specifically laboratory) environments. This is because elevated, particularly chronic, stress responses can result in altered physiological, neurological and behavioural states that have the potential to compromise the validity of scientific results. Selective breeding in captivity to, for example, maximise production, select for docile temperament or specific genotypes for biomedical research, is likely to be counter to natural selective pressures for evolutionary fitness. Given that many natural selective pressures active in the wild are absent in captivity, this paper reviews the selective breeding of primates (especially Old World monkeys) in captivity, its potential negative effects, and options that exist for ameliorating these negative effects.

Keywords

animal welfarebiomedical researchbreeding facilitiesmacaquesOld World primatesselective breeding
Type
Research Article
Information
Animal Welfare , Volume 19 , Issue S1: Proceedings of the UFAW International Symposium ‘Darwinian selection, selective breeding and the welfare of animals’ Bristol, 2009 , May 2010 , pp. 57 - 65
Copyright
© 2010 Universities Federation for Animal Welfare

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