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Plasma concentration of leptin and ghrelin in Standardbred foals as related to the age, sex, exercise and training

Published online by Cambridge University Press:  01 April 2008

W. Kędzierski  and
M. Kapica
W. Kędzierski*
Affiliation:
Department of Animal Biochemistry and Physiology, Faculty of Veterinary Medicine, Agricultural University, Akademicka 12, 20-033 Lublin, Poland
M. Kapica
Affiliation:
Department of Animal Biochemistry and Physiology, Faculty of Veterinary Medicine, Agricultural University, Akademicka 12, 20-033 Lublin, Poland
*
E-mail: witold.kedzierski@ar.lublin.pl
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Abstract

The effect of acute exercise was studied in a group of 42 clinically healthy young Standardbred trotters. These trotters had been divided into four groups according to their age. Their ages were from 1.5 to 3 years. Three jugular venous blood samples were collected via venipuncture from each horse. These samples were collected while (1) at rest, (2) after the end of the exercise and (3) 30 min after the end of the exercise. Exercise showed a significant increase in plasma leptin concentration (3.8 ± 0.31 at rest v. 4.3 ± 0.37 just after exercise and 4.4 ± 0.47 ng/ml after a 30-min rest; ANOVA P < 0.05). The difference between values obtained 30 min after exercise and at rest was significantly greater in 1.5-year-old horses than in those aged 2.5 years (+1.3 ± 0.43 v. +0.1 ± 0.15 ng/ml; ANOVA P < 0.05). The mean plasma leptin concentration was higher in fillies than in colts (4.9 ± 0.47 v. 3.5 ± 0.36 ng/ml; ANOVA P < 0.05). A positive correlation between the plasma concentrations of leptin and triacylglycerides measured just after exercise was detected (r = 0.65). The acute exercise significantly increased the plasma concentration of ghrelin that was measured just after exercise (1255 ± 55.9 v. 1127 ± 54.2 pg/ml; ANOVA P < 0.05). The exercise-induced age-related changes in the plasma ghrelin concentration were significantly lower in 2.5-year-old trotters than in 1.5-year olds. To sum up, the changes in plasma leptin and ghrelin concentrations during bouts of exertion tend to decrease with age and/or training of Standardbred foals.

Keywords

ghrelinleptintraininghorse
Type
Full Paper
Information
animal , Volume 2 , Issue 4 , April 2008 , pp. 582 - 587
Copyright
Copyright © The Animal Consortium 2008

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