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A Model for Ischaemic Heart Disease and Stroke III: Applications

Published online by Cambridge University Press:  10 May 2011

T. Chatterjee ,
A. S. Macdonald  and
H. R. Waters
H. R. Waters
Affiliation:
Department of Actuarial Mathematics and Statistics, and the Maxwell Institute for Mathematical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, U.K., Email: H.R.Waters@hw.ac.uk
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Abstract

This is the third in a series of three papers. In the first paper we describe a comprehensive stochastic model of an individual's lifetime that includes diagnosis with ischaemic heart disease and stroke and also the development of the major risk factors for these conditions. The second paper discusses in some detail models for changes in body mass index (BMI) and also the effects of these changes, in particular the current trend towards increasing prevalence of obesity, on diabetes, cardiovascular diseases and expected future lifetime. This paper is devoted to the following applications of the model described in the first paper:

(a) quantifying the effects of smoking and of changes in smoking habits, and,

(b) quantifying the effects of treatment with statins (drugs designed to lower cholesterol).

Keywords

DiabetesFramingham Heart StudyHypercholesterolaemiaHypertensionIschaemic Heart DiseaseMarkov ModelMortalitySmokingStatinsStroke
Type
Papers
Information
Annals of Actuarial Science , Volume 3 , Issue 1-2 , September 2008 , pp. 105 - 119
Copyright
Copyright © Institute and Faculty of Actuaries 2008

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References

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