Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-10T23:54:16.328Z Has data issue: false hasContentIssue false
  • English
  • Français

The origin of addictions by means of unnatural decision

Published online by Cambridge University Press:  29 July 2008

Serge H. Ahmed
Serge H. Ahmed
Affiliation:
Movement Adaptation Cognition, Université Bordeaux 2, Université Bordeaux 1, CNRS, UMR5227, Bordeaux 33076, France. sahmed@u-bordeaux2.frhttp://www.inb.u-bordeaux2.fr
Get access Rights & Permissions [Opens in a new window]

Abstract

The unified framework for addiction (UFA) formulated by Redish et al. is a tour de force. It uniquely predicts that there should be multiple addiction syndromes and pathways – a diversity that would reflect the complexity of the mammalian brain decision system. Here I explore some of the evolutionary and developmental ramifications of UFA and derive several new avenues for research.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 31 , Issue 4 , August 2008 , pp. 437 - 438
Copyright
Copyright © Cambridge University Press 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ahmed, S. H. & Cador, M. (2006) Dissociation of psychomotor sensitization from compulsive cocaine consumption. Neuropsychopharmacology 31:563–71.CrossRefGoogle ScholarPubMed
Ahmed, S. H., Kenny, P. J., Koob, G. F. & Markou, A. (2002) Neurobiological evidence for hedonic allostasis associated with escalating cocaine use. Nature Neuroscience 5:625–66.CrossRefGoogle ScholarPubMed
Ahmed, S. H., Lin, D., Koob, G. F. & Parsons, L. H. (2003) Escalation of cocaine self-administration does not depend on altered cocaine-induced nucleus accumbens dopamine levels. Journal of Neurochemistry 86:102–13.CrossRefGoogle Scholar
Ahmed, S. H., Lutjens, R., van der Stap, L. D., Lekic, D., Romano-Spica, V., Morales, M., Koob, G. F., Repunte-Canonigo, V., Sanna, P. P. (2005) Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction. Proceeding of the National Academy of Sciences USA 102:11533–38.CrossRefGoogle ScholarPubMed
Baumeister, R. F. & Heatherton, T. F. (1996) Self-regulation failure: An overview. Psychological Inquiry 7:1–15.CrossRefGoogle Scholar
Blakemore, S. J. (2008) The social brain in adolescence. Nature Reviews Neuroscience 9:267–77.CrossRefGoogle ScholarPubMed
Dickinson, A. & Balleine, B. (1994) Motivational control of goal-directed action. Animal Learning and Behavior 22:1–18.CrossRefGoogle Scholar
Ernst, M., Pine, D. S. & Hardin, M. (2006) Triadic model of the neurobiology of motivated behavior in adolescence. Psychological Medicine 36:299–312.CrossRefGoogle ScholarPubMed
Lenoir, M., Serre, F., Cantin, L. & Ahmed, S. H. (2007) Intense sweetness surpasses cocaine reward. PLoS ONE 2 (8):e698.CrossRefGoogle ScholarPubMed
Mantsch, J. R., Yuferov, V., Mathieu-Kia, A. M., Ho, A. & Kreek, M. J. (2004) Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. Psychopharmacology 175:26–36.CrossRefGoogle ScholarPubMed
McClure, S. M., Laibson, D. I., Loewenstein, G. & Cohen, J. D. (2004) Separate neural systems value immediate and delayed monetary rewards. Science 306(5695):503–507.CrossRefGoogle ScholarPubMed
Paterson, N. E. & Markou, A. (2003) Increased motivation for self-administered cocaine after escalated cocaine intake. Neuroreport 14:2229–32.CrossRefGoogle ScholarPubMed
Roberts, W. A. (2002) Are animals stuck in time? Psychological Bulletin 128:473–489.CrossRefGoogle ScholarPubMed
Searle, J. R. (2001) Rationality in action. MIT Press.Google Scholar
Suddendorf, T. & Corballis, M. C. (2007) The evolution of foresight: What is mental time travel, and is it unique to humans? Behavioral and Brain Sciences 30:298–313.CrossRefGoogle ScholarPubMed
Thaler, R. H. & Shefrin, H. M. (1981) An economic theory of self-control. Journal of Political Economy 89:392–406.CrossRefGoogle Scholar