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Are delusions biologically adaptive? Salvaging the doxastic shear pin

Published online by Cambridge University Press:  28 January 2010

Aaron L. Mishara  and
Phil Corlett
Aaron L. Mishara
Affiliation:
Department of Psychiatry, Brain Mapping Unit and Behavioural and Clinical Neurosciences Institute, University of Cambridge, School of Clinical Medicine, and Addenbrooke's Hospital, Cambridge CB2 2QQ, United Kingdomaaron.mishara@yale.edu Department of Psychiatry, Clinical Neuroscience Research Unit, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT 06519
Phil Corlett
Affiliation:
Department of Psychiatry, Brain Mapping Unit and Behavioural and Clinical Neurosciences Institute, University of Cambridge, School of Clinical Medicine, and Addenbrooke's Hospital, Cambridge CB2 2QQ, United Kingdomaaron.mishara@yale.edu Department of Psychiatry, Abraham Ribicoff Research Facilities, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT 06519. philip.corlett@yale.edu
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Abstract

In their target article, McKay & Dennett (M&D) conclude that only “positive illusions” are adaptive misbeliefs. Relying on overly strict conceptual schisms (deficit vs. motivational, functional vs. organic, perception vs. belief), they prematurely discount delusions as biologically adaptive. In contrast to their view that “motivation” plays a psychological but not a biological function in a two-factor model of the forming and maintenance of delusions, we propose a single impairment in prediction-error–driven (i.e., motivational) learning in three stages in which delusions play a biologically adaptive role.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 32 , Issue 6 , December 2009 , pp. 530 - 531
Copyright
Copyright © Cambridge University Press 2010

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References

Adams, C. D. & Dickinson, A. (1981) Actions and habits: Variations in associative representations during instrumental learning. In: Information processing in animals: Memory mechanisms, ed. Spear, N. E. & Miller, R. R., pp. 143–66. Erlbaum.Google Scholar
Binswanger, L. (1965) Wahn. Neske.Google Scholar
Conrad, K. (1958) Die beginnende Schizophrenie. Versuch einer Gestaltanalyse des Wahns. Thieme.Google Scholar
Corlett, P. R., Frith, C. D. & Fletcher, P. C. (2009a) From drugs to deprivation: A Bayesian framework for understanding models of psychosis. Psychopharmacology 206(4):515–30.CrossRefGoogle ScholarPubMed
Corlett, P. R., Honey, G. D. & Fletcher, P. C. (2007) From prediction error to psychosis: Ketamine as a pharmacological model of delusions. Journal of Psychopharmacology 21(3):238–52.Google Scholar
Corlett, P. R., Krystal, J. K., Taylor, J. R. & Fletcher, P. C. (2009b) Why do delusions persist? Frontiers in Human Neuroscience 3. Available at: http://www.frontiersin.org/humanneuroscience/paper/10.3389/neuro.09/012.2009/html/Google Scholar
Davies, M. & Coltheart, M. (2000) Introduction: Pathologies of belief. In: Pathologies of belief, ed. Coltheart, M. & Davies, M., pp. 1–46. Blackwell.Google Scholar
Daw, N. D., Niv, Y. & Dayan, P. (2005) Uncertainty-based competition between prefrontal and dorsolateral striatal systems for behavioral control. Nature Neuroscience 8(12):1704–11.Google Scholar
Dickinson, A. & Shanks, D. (1995) Instrumental action and causal representation. In: Causal cognition: A multidisciplinary debate, ed. Sperber, D., Premack, D. & Premack, A. J., pp. 5–25. Oxford University Press.Google Scholar
Eisenhardt, D. & Menzel, R. (2007) Extinction learning, reconsolidation and the internal reinforcement hypothesis. Neurobiology of Learning and Memory 87(2):167–73.CrossRefGoogle ScholarPubMed
Fletcher, P. C. & Frith, C. D. (2009) Perceiving is believing: A Bayesian approach. Nature Reviews Neuroscience 10(1):48–58.Google Scholar
Fuster, J. M. (2006) The cognit: A network model of cortical representation. International Journal of Psychophysiology 60(2):125–32.Google Scholar
Haggard, P., Aschersleben, G., Gehrke, J. & Prinz, W. (2002) Action, binding and awareness. In Attention and performance XIX: Common mechanisms in perception and action, ed. Hommel, B. & Prinz, W., pp. 266–85. Oxford University Press.CrossRefGoogle Scholar
Hemsley, D. R. & Garety, P. A. (1986) The formation of maintenance of delusions: A Bayesian analysis. British Journal of Psychiatry 149(July):51–56.CrossRefGoogle ScholarPubMed
Hitchcott, P. K., Quinn, J. J. & Taylor, J. R. (2007) Bidirectional modulation of goal directed actions by prefrontal cortical dopamine. Cerebral Cortex 17(12):2820–27.CrossRefGoogle ScholarPubMed
Jaspers, K. (1963) General psychopathology, 7th edition, trans. Hoenig, J. & Hamilton, M. W.. The Johns Hopkins University Press. (Originally published in 1946.)Google Scholar
Kapur, S. (2003) Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia. American Journal of Psychiatry 160(1):13–23.CrossRefGoogle ScholarPubMed
Kraus, A. (1997) Technical delusions as form of stabilisation [Le Delire technique comme forme de stabilisation]. Evolution Psychiatrique 62(2):381–99.Google Scholar
McGhie, A. & Chapman, J. (1961) Disorders of attention and perception in early schizophrenia. British Journal of Medical Psychology 34:103–16.CrossRefGoogle ScholarPubMed
McKay, R., Langdon, R. & Coltheart, M. (2007a) Models of misbelief: Integrating motivational and deficit theories of delusions. Consciousness and Cognition 16:932–41.Google Scholar
Miller, R. (2008) A neurodynamic theory of schizophrenia (and related disorders). Lulu.Google Scholar
Milton, F., Patwa, V. K. & Hafner, R. J. (1978) Confrontation vs. belief modification in persistently deluded patients. British Journal of Medical Psychology 51(2):127–30.Google Scholar
Mishara, A. L. (2007a) Is minimal self preserved in schizophrenia? A subcomponents view. Consciousness and Cognition 16(3):715–21.CrossRefGoogle ScholarPubMed
Mishara, A. L. (2007b) Missing links in phenomenological clinical neuroscience? Why we are still not there yet. Current Opinion in Psychiatry 60(20):559–69.CrossRefGoogle Scholar
Mishara, A. L. (in press a) Kafka's doubles, paranoia and the brain: Hypnagogic vs. hyper-reflexive models of disruption of self in neuropsychiatric disorders and anomalous conscious states. Philosophy, Ethics, and Humanities in Medicine (PEHM), PubMed Central Open Access Journal. Available at: http://www.peh-med.com/Google Scholar
Mishara, A. L. (in press b) The unconscious in paranoid delusional psychosis? Phenomenology, nuroscience, psychoanalysis. In: Founding psychoanalysis, ed. Lohmar, D. & Bruzinska, J.. Springer.Google Scholar
Mishara, A. L. (2010) Klaus Conrad (1905–1961): Delusional mood, psychosis and beginning schizophrenia. Schizophrenia Bulletin 36(1):9–13.Google Scholar
Tsuang, M. T., Faraone, S. V. & Day, M. (1988) Schizophrenic disorders. In: The new Harvard guide to psychiatry, ed. Nicholi, A. Jr., pp. 259–95. Belknap Press.Google Scholar
Uhlhaas, P. J. & Mishara, A. L. (2007) Perceptual anomalies in schizophrenia: Integrating phenomenology and cognitive neuroscience. Schizophrenia Bulletin 33(1):142–56.Google Scholar
von Weizsäcker, V., (1950) Der Gestaltkreis. Theorie der Einheit von Wahrnnehmen und Bewegen 4. Aufl. (4th edition). Georg Thieme Verlag.Google Scholar
von Weizsäcker, V. (1956) Pathosophie. Vandenhoeck & Ruprecht.Google Scholar
Wegner, D. M. (2004) Précis of The illusion of conscious will. Behavioral and Brain Sciences 27 (5):649–59; discussion660–92.CrossRefGoogle ScholarPubMed