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Inactivation and adaptation of number neurons

Published online by Cambridge University Press:  27 August 2009

J. Patrick Mayo
Affiliation:
Department of Neuroscience, Center for the Neural Basis of Cognition, Center for Neuroscience at the University of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15260. jpm49@pitt.edu

Abstract

Single-neuron recordings may help resolve the issue of abstract number representation in the parietal lobes. Two manipulations in particular – reversible inactivation and adaptation of apparent numerosity – could provide important insights into the causal influence of “numeron” activity. Taken together, these tests can significantly advance our understanding of number processing in the brain.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2009

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References

Burr, D. & Ross, J. (2008) A visual sense of number. Current Biology 18:425–28.CrossRefGoogle ScholarPubMed
Diester, I. & Nieder, A. (in press) Numerical values leave a semantic imprint on associated signs in monkeys. Journal of Cognitive Neuroscience.Google Scholar
Durgin, F. H. (2008) Texture density adaptation and visual number revisited. Current Biology 18:R855–56; author reply R857–58.CrossRefGoogle ScholarPubMed
Li, C. S., Mazzoni, P. & Andersen, R. A. (1999) Effect of reversible inactivation of macaque lateral intraparietal area on visual and memory saccades. Journal of Neurophysiology 81:1827–38.CrossRefGoogle ScholarPubMed
Nieder, A. & Merten, K. (2007) A labeled-line code for small and large numerosities in the monkey prefrontal cortex. Journal of Neuroscience 27:5986–93.CrossRefGoogle ScholarPubMed
Wardak, C., Olivier, E. & Duhamel, J.-R. (2002) Saccadic target selection deficits after lateral intraparietal area inactivation in monkeys. Journal of Neuroscience 22:9877–84.CrossRefGoogle ScholarPubMed