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The Alchemy of Clinical Trials

Published online by Cambridge University Press:  01 March 2007

Catherine M. Will
Catherine M. Will
Affiliation:
Department of Sociology, University of Sussex, Falmer, East Sussex BN1 9SN, UK E-mail: c.will@sussex.ac.uk
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Abstract

This article considers the complex construction of randomized controlled trials that lies behind the rhetoric of the gold standard. Drawing on insights from Science and Technology Studies and empirical material, I argue that trials in the field of cardiovascular disease prevention are constituted as ‘research’ rather than ‘science’. In these examples, control emerges out of a dual concern with practices of purification and involvement of aspects of the world outside the experiment, as the designers of trials aspire to relevance as well as rigour. Such strategies of ‘contextualization’ mean that trials are more like alchemy than assay, proceeding by complex moves to transform ‘base’ matters rather than distilling elements of clinical practice.

Keywords

boundary workclinical trialcontextualization RCTtransaction space
Type
Articles
Information
BioSocieties , Volume 2 , Issue 1: Special Issue: The Construction and Governance of Randomised Controlled Trials , March 2007 , pp. 85 - 99
Copyright
Copyright © London School of Economics and Political Science 2007

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