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Lesions of Left Basal Ganglia and Insula Structures Impair Executive Functions but not Emotion Recognition: A Case Report

Published online by Cambridge University Press:  06 December 2016

Domagoj Švegar ,
Ronald Antulov ,
Mladenka Tkalčić  and
Igor Antončić
Domagoj Švegar*
Affiliation:
Department of Psychology, Faculty of Humanities and Social Sciences, University of Rijeka, Rijeka, Croatia
Ronald Antulov
Affiliation:
Department of Radiology, Clinical Hospital Center Rijeka, Rijeka, Croatia
Mladenka Tkalčić
Affiliation:
Department of Psychology, Faculty of Humanities and Social Sciences, University of Rijeka, Rijeka, Croatia
Igor Antončić
Affiliation:
Department of Radiology, Clinical Hospital Center Rijeka, Rijeka, Croatia
*
Address for correspondence: Domagoj Švegar, Department of Psychology, Faculty of Humanities and Social Sciences, University of Rijeka, Filozofski fakultet u Rijeci, Odsjek za psihologiju, Sveucilisna avenija 4, 51000 Rijeka, Croatia (HR). Phone: +385 51 265 770. E-mail: dsvegar@ffri.hr
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Abstract

Increasing research evidence suggests that basal ganglia are an important part of frontal-subcortical circuit which is involved not only in motor control but also in affective, cognitive and executive functions. In this article, we describe the ability of facial emotion recognition and cognitive functioning in a patient with left basal ganglia and insula damage. The patient's ability to recognise facial emotional expressions was intact in spite of unilateral injury of the left insula and basal ganglia. He showed preserved intellectual function in general, but experienced difficulties on subsets of the executive functions: set-shifting and ability to activate or generate cognitive strategies, commonly found in patients with caudate lesions. This case contributes to evidence that striatal structures are important for executive functions.

Keywords

basal gangliainsulaemotion recognitionexecutive functionsinfarction
Type
Articles
Information
Brain Impairment , Volume 17 , Issue 3 , December 2016 , pp. 233 - 241
Copyright
Copyright © Australasian Society for the Study of Brain Impairment 2016 

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References

Adolphs, R., Damasio, H., Tranel, D., Cooper, G., & Damasio, A.R. (2000). A role for somatosensory cortices in the visual recognition of emotion as revealed by three-dimensional lesion mapping. The Journal of Neuroscience, 20 (7), 2683–2690.Google Scholar
Adolphs, R., Tranel, D., Koenigs, M., & Damasio, A.R. (2005). Preferring one taste over another without recognizing either. Nature Neuroscience, 8 (7), 860–861.Google Scholar
Alexander, G.E., DeLong, M.R., & Strick, P.L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual Review of Neuroscience, 9 (1), 357–381.Google Scholar
Anderson, A.K., Christoff, K., Panitz, D., De Rosa, E., & Gabrieli, J.D. (2003). Neural correlates of the automatic processing of threat facial signals. The Journal of Neuroscience, 23 (13), 5627–5633.CrossRefGoogle ScholarPubMed
Backman, L., Robins-Wahlin, T.B., Lundin, A., Ginovart, N., & Farde, L. (1997). Cognitive deficits in Huntington's disease are predicted by dopaminergic PET markers and brain volumes. Brain, 120 (12), 2207–2217.CrossRefGoogle ScholarPubMed
Birn, R.M., Kenworthy, L., Case, L., Caravella, R., Jones, T.B., Bandettini, P.A., & Martin, A. (2010). Neural systems supporting lexical search guided by letter and semantic category cues: A self-paced overt response fMRI study of verbal fluency. Neuroimage, 49 (1), 1099–1107.Google Scholar
Bonelli, R.M., & Cummings, J.L. (2007). Frontal-subcortical circuitry and behavior. Dialogues in Clinical Neuroscience, 9 (2), 141.Google Scholar
Calder, A.J., Keane, J., Manes, F., Antoun, N., & Young, A.W. (2000). Impaired recognition and experience of disgust following brain injury. Nature Neuroscience, 3 (11), 1077–1078.Google Scholar
Calvo, M.G., & Lundqvist, D. (2008). Facial expressions of emotion (KDEF): Identification under different display-duration conditions. Behavior Research Methods, 40 (1), 109–115.CrossRefGoogle ScholarPubMed
Ekman, P., & Friesen, W.V. (1976). Pictures of facial affect. Palo Alto, CA: Consulting Psychologists Press.Google Scholar
Elliott, R. (2003). Executive functions and their disorders. British Medical Bulletin, 65 (1), 49–59.CrossRefGoogle ScholarPubMed
Galić, S. (2002). Neuropsihologijska procjena: Testovi i tehnike. Jastrebarsko: Naklada Slap.Google Scholar
Heaton, R.K., Chelune, G.J., Talley, J.L., Kay, G.G., & Curtiss, J. (1993). Wisconsin card sorting test manual. Odessa, FL: Psychological Assessment Resources.Google Scholar
Huang, Y., Tang, S., Helmeste, D., Shioiri, T., & Someya, T. (2001). Differential judgement of static facial expressions of emotions in three cultures. Psychiatry and Clinical Neurosciences, 55 (5), 479–483.Google Scholar
Johnson, S.A., Stout, J.C., Solomon, A.C., Langbehn, D.R., Aylward, E.H., Cruce, C.B., . . . & Predict-HD Investigators of the Huntington Study Group. (2007). Beyond disgust: Impaired recognition of negative emotions prior to diagnosis in Huntington's disease. Brain, 130 (7), 1732–1744.Google Scholar
Jones-Gotman, M., & Milner, B. (1977). Design fluency: The invention of nonsense drawings after focal cortical lesions. Neuropsychologia, 15 (4–5), 653–674.Google Scholar
Kaplan, E., Goodglass, H., & Weintraub, S. (1983). The Boston Naming Test. Philadelphia: Lea & Febiger.Google Scholar
Levy, R., & Dubois, B. (2006). Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cerebral Cortex, 16 (7), 916–928.CrossRefGoogle ScholarPubMed
Lezak, M.D., Howieson, D.B., Bigler, E.D., & Tranel, D. (2012). Neuropsychological assessment. New York: Oxford University Press.Google Scholar
Lichter, D.G., & Cummings, J.L. (Eds.) (2001). Frontal-subcortical circuits in psychiatric and neurological disorders. New York: The Guilford Univeristy Press.Google Scholar
Lundqvist, D., Flykt, A., & Öhman, A. (1998). The Karolinska Directed Emotional Faces - KDEF, CD ROM from Department of Clinical Neuroscience, Psychology section, Karolinska Institutet, ISBN 91-630-7164-9.CrossRefGoogle Scholar
Matsumoto, D., & Ekman, P. (1988). Japanese and caucasian facial expressions of emotion (JACFEE) and neutral faces. San Francisco: Department of Psychiatry, University of California.Google Scholar
Meyers, J.E. & Meyers, K.R. (1995). Rey complex figure test and recognition trial : RCFT : professional manual. Odessa: PAR.Google Scholar
Middleton, F.A., & Strick, P.L. (2002). Basal-ganglia ‘projections’ to the prefrontal cortex of the primate. Cerebral Cortex, 12 (9), 926–935.Google Scholar
Milovanović, T., Švegar, D., & Kardum, I. (2013). Efekti anksioznosti i depresivnosti na prepoznavanje emocionalnih izraza lica. Psihologijske teme, 22 (1), 29–49.Google Scholar
Palermo, R., & Coltheart, M. (2004). Photographs of facial expression: Accuracy, response times, and ratings of intensity. Behavior Research Methods, Instruments, & Computers, 36 (4), 634–638.Google Scholar
Phillips, M.L., Williams, L.M., Heining, M., Herba, C.M., Russell, T., Andrew, C., . . . Gray, J.A. (2004). Differential neural responses to overt and covert presentations of facial expressions of fear and disgust. Neuroimage, 21 (4), 1484–1496.Google Scholar
Phillips, M.L., Young, A.W., Senior, C., Brammer, M., Andrew, C., Calder, A.J., . . . David, A.S. (1997). A specific neural substrate for perceiving facial expressions of disgust. Nature, 389 (6650), 495–498.Google Scholar
Postuma, R.B., & Dagher, A. (2006). Basal ganglia functional connectivity based on a meta-analysis of 126 positron emission tomography and functional magnetic resonance imaging publications. Cerebral Cortex, 16 (10), 1508–1521.Google Scholar
Ruiz, S., Lee, S., Soekadar, S.R., Caria, A., Veit, R., Kircher, T., . . . Sitaram, R. (2013). Acquired self‐control of insula cortex modulates emotion recognition and brain network connectivity in schizophrenia. Human Brain Mapping, 34 (1), 200–212.CrossRefGoogle ScholarPubMed
Salmon, D.P., Heindel, W.C., & Hamilton, J.M. (2001). Cognitive abilities mediated by frontal-subcortical circuits. In Lichter, D.G. and Cummings, J.L. (Eds.), Frontal-subcortical circuits in psychiatric and neurological disorders (pp. 114–150). New York: The Guilford Univeristy Press.Google Scholar
Schroeder, U., Hennenlotter, A., Erhard, P., Haslinger, B., Stahl, R., Lange, K.W., & Ceballos‐Baumann, A.O. (2004). Functional neuroanatomy of perceiving surprised faces. Human Brain Mapping, 23 (4), 181–187.Google Scholar
Shulman, K.I. (2000). Clock‐drawing: is it the ideal cognitive screening test?. International Journal of Geriatric Psychiatry, 15 (6), 548–561.3.0.CO;2-U>CrossRefGoogle ScholarPubMed
Sprengelmeyer, R., Rausch, M., Eysel, U.T., & Przuntek, H. (1998). Neural structures associated with recognition of facial expressions of basic emotions. Proceedings of the Royal Society of London B: Biological Sciences, 265 (1409), 1927–1931.CrossRefGoogle ScholarPubMed
Strauss, E., Sherman, E.M.S., & Spreen, O. (2006). A compendium of neuropsychological tests. Administration, norms, and commentary. Oxford: Oxford University Press.Google Scholar