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Bioavailability of β-carotene (βC) from purple carrots is the same as typical orange carrots while high-βC carrots increase βC stores in Mongolian gerbils(Meriones unguiculatus)

Published online by Cambridge University Press:  08 March 2007

Mandy Porter Dosti ,
Jordan P. Mills ,
Philipp W. Simon  and
Sherry A. Tanumihardjo
Mandy Porter Dosti
Affiliation:
Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA
Jordan P. Mills
Affiliation:
Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA
Philipp W. Simon
Affiliation:
United States Department of Agriculture Agricultural Research Service, Vegetable Crops Research Unit, Department of Horticulture, University of Wisconsin-Madison, Madison, WI 53706, USA
Sherry A. Tanumihardjo*
Affiliation:
Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA
*
*Corresponding author: Dr Sherry A. Tanumihardjo, fax +1 608 262 5860, email sherry@nutrisci.wisc.edu
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Abstract

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Vitamin A (VA) deficiency is a worldwide public health problem. Biofortifying existing sources of β-carotene (βC) and increasing dietary βC could help combat the issue. Two studies were performed to investigate the relative βC bioavailability of a βC supplement to purple, high-βC orange, and typical orange carrots using Mongolian gerbils (Meriones unguiculatus). In study 1, which used a traditional bioavailability design, gerbils (n32) received a diet containing orange, purple, or white carrot powder, or white carrot powder +a βC supplement. In study 2, which included βC-biofortified carrots, gerbils (n 39) received orange, high-βC orange, purple, or white carrot powder in their diet. Both studies lasted 21 d and the gerbils were killed to determine the effect of carrot type or supplement on serum and liver βC, α-carotene, and VA concentrations. Liver stores of βC or VA in the gerbils did not differ between orange and purple carrot diets when equal amounts of βC from each of the diets were consumed (P>0·05). Both the orange and purple carrot diet resulted in higher liver VA compared with the supplement (P<0·05). High-βC carrots resulted in more than 2-fold higher βC and 1·1 times greater VA liver stores compared with typical orange carrots (P<0·05). These results suggest that high-βC carrots may be an alternative source of VA to typical carrots in areas of VA deficiency. Second, phenolics including anthocyanins and phenolic acids in purple carrot do not interfere with the bioavailability of βC from purple carrots.

Keywords

β-CaroteneGerbilsVitamin ACarrotsBiofortification
Type
Research Article
Information
British Journal of Nutrition , Volume 96 , Issue 2 , August 2006 , pp. 258 - 267
Copyright
Copyright © The Nutrition Society 2006

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