Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-10T16:00:22.619Z Has data issue: false hasContentIssue false
  • English
  • Français

The cholesterol-raising effect of coffee in the Syrian hamster

Published online by Cambridge University Press:  09 March 2007

T. A. B. Sanders  and
Sanoja Sandaradura
T. A. B. Sanders
Affiliation:
Department of Nutrition and Dietetics, King's College, University of London, Campden Hill Road, London W8 7AH
Sanoja Sandaradura
Affiliation:
Department of Nutrition and Dietetics, King's College, University of London, Campden Hill Road, London W8 7AH
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Adult male Syrian hamsters were fed on a high-fat diet with or without access to boiled coffee. Plasma total, low-density-lipoprotein- and high-density-lipoprotein-cholesterol and triacylglycerol concentrations were increased by the coffee and very-low-density-lipoprotein-cholesterol concentrations were lowered. It is concluded that the Syrian hamster is a suitable animal model in which to study the hypercholesterolaemic effect of coffee

Keywords

CholesterolLipoproteinsCoffeeSyrian hamster
Type
Effects of Diet on Lipid Metabolism
Information
British Journal of Nutrition , Volume 68 , Issue 2 , September 1992 , pp. 431 - 434
Copyright
Copyright © The Nutrition Society 1992

References

REFERENCES

Bak, A. A. & Grobbee, D. E. (1989). The effect on serum cholesterol levels of coffee brewed by filtering or boiling. New England Journal of Medicine 321, 1432–1437.CrossRefGoogle ScholarPubMed
Ohtani, H., Hayashi, K., Hirata, Y., Dojo, S., Nakashima, K., Nishio, E., Kurushima, H., Saeki, M. & Kajiyama, G. (1990). Effects of dietary cholesterol and fatty acids on plasma cholesterol level and hepatic protein metabolism. Journal of Lipid Research 31, 1413–1422.CrossRefGoogle Scholar
Reichl, D. & Miller, N. E. (1989). Pathophysiology of reverse cholesterol transport. Insights from inherited disorders of lipoprotein metabolism. Arteriosclerosis 9, 785–797.CrossRefGoogle ScholarPubMed
Spady, D. K. & Dietschy, J. M. (1988). Interaction of dietary cholesterol and triglycerides in the regulation of hepatic low density lipoprotein transport in the hamster. Journal of Clinical Investigation 81, 300–309.CrossRefGoogle ScholarPubMed
Spady, D. K. & Dietschy, J. M. (1989). Interaction of aging and dietary fat in the regulation of low density lipoprotein transport in the hamster. Journal of Lipid Research 30, 559–569.CrossRefGoogle ScholarPubMed
Terpstra, A. H. M., Woodward, C. J. H. & Sanchez-Muniz, F. J. (1981). Improved techniques for separation of serum lipoproteins by density gradient ultracentrifugation: visualization by prestaining and rapid separation of serum lipoproteins from small volumes of serum. Analytical Biochemistry 111, 149–157.CrossRefGoogle ScholarPubMed
Thelle, D. S., Heyden, S. & Fodor, J. G. (1987). Coffee and cholesterol in epidemiological and experimental studies. Atherosclerosis 67, 97–103.CrossRefGoogle ScholarPubMed
Tverdal, A., Stensvold, I., Solvoll, K., Foss, O. P., Lund-Larsen, P. & Bjartveit, K. (1990). Coffee consumption and death from coronary heart disease in middle-aged Norwegian men and women. British Medical Journal 300, 566–569.CrossRefGoogle ScholarPubMed
Widdowson, E. M. (1986). Animals in the service of human nutrition. In Proceedings of the XIIIth International Congress of Nutrition, pp. 52–57 [Taylor, T. G. and Jenkins, N. K., editors]. London: John Libbey.Google Scholar
Williams, P. T., Wood, P. D., Vranizan, K. M., Albers, J. J., Garay, S. C. & Taylor, C. B. (1985). Coffee intake and elevated cholesterol and apoprotein B levels in men. Journal of the American Medical Association 253, 1407–1411.CrossRefGoogle ScholarPubMed
Zock, P. L., Katan, M. B., Merkus, M. P., van Dusseldorp, M. & Harrycan, J. L. (1990). Effect of a lipid-rich fraction from boiled coffee on serum cholesterol. Lancet 335, 1235–1237.CrossRefGoogle ScholarPubMed