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Effect of dietary protein concentration on responses to Escherichia coli endotoxin in broiler chickens

Published online by Cambridge University Press:  09 March 2007

Kazuaki Takahashi ,
Shinichi Yodogawa ,
Yukio Akiba  and
Keiji Tamura
Kazuaki Takahashi
Affiliation:
Department of Animal Science, Faculty of Agriculture, Tohoku University, Sendai-shiJapan981
Shinichi Yodogawa
Affiliation:
Department of Animal Science, Faculty of Agriculture, Tohoku University, Sendai-shiJapan981
Yukio Akiba
Affiliation:
Department of Animal Science, Faculty of Agriculture, Tohoku University, Sendai-shiJapan981
Keiji Tamura
Affiliation:
Saikin Kagaku Institute, Sendai-shiJapan981
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Abstract

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The effect of dietary protein concentration on stress responses against injection of Escherichia coli lipopolysaccharide (LPS) was studied in male broiler chickens. Chickens (7 d of age) were fed on a 100 (low-protein; LP) or 300 g protein/kg (high-protein; HP) diet for 2 weeks. LPS was injected intraperitoneally every 2 d during the final 6 d, or once 16 h before the end of the experiment, at a concentration of 900 μg/chick. The LPS injection did not affect body-weight gain, feed intake, gain:intake ratio, or plasma Fe concentration. The single injection of LPS reduced plasma Zn concentration, but the repeated injections did not. Feeding the HP diet increased the response of plasma Zn concentration to the single injection of LPS. Plasma albumin concentration was reduced by LPS injection. Feeding the HP diet resulted in a higher plasma α 1-acid glycoprotein (AGP) concentration than feeding the LP diet, in chicks untreated with LPS. An increase in plasma AGP concentration observed after LPS injection in chicks fed on the LP diet was greater than that seen in chicks fed on the HP diet. No significant changes in plasma AGP concentration in response to repeated injections of LPS were observed in chicks fed on the HP diet. Plasma interleukin-1 (IL-l)-like activity was greater in chicks fed on the LP diet than in those fed on the HP diet, when LPS was injected. The response of plasma IL-1-like activity to the single injection of LPS in chicks fed on the LP diet was the greatest among the treatment groups. These results suggest that acute-phase responses to LPS injection are much greater in chicks fed on a LP diet than in those fed on a HP diet, and multiple injection of LPS weakens the responses.

Keywords

Acute-phase responseDietary proteinLipopolysaccharide
Type
Effects of dietary protein in chickens
Information
British Journal of Nutrition , Volume 74 , Issue 2 , August 1995 , pp. 173 - 182
Copyright
Copyright © The Nutrition Society 1995

References

REFERENCES

Akiba, Y. & Matsumoto, T. (1978) Effect of force-feeding and dietary cellulose on liver lipid accumulation and lipid composition of liver and plasma in growing chicks. Journal of Nutrition 108, 739–748.CrossRefGoogle ScholarPubMed
Amrani, D. L., Mauzy-Melity, D. & Mossessen, M. W. (1986) Effect of hepatic-stimulating factor and glucocorticoids on plasma fibronectin level. Biochemical Journal 238, 365–371.CrossRefGoogle Scholar
Beisel, W. R. (1977) Magnitude of the host nutritional responses to infection. American Journal of Clinical Nutrition 30, 1239–1247.CrossRefGoogle ScholarPubMed
Bennett, M. & Schmid, K. (1980) Immunosuppression by human plasma α1 acid glycoprotein: importance of the carbohydrate moiety. Proceedings of the National Academy of Sciences USA 77, 6109–6113.CrossRefGoogle Scholar
Benson, B. N., Calvert, C. C., Roura, E. & Klasing, K. C. (1993) Dietary energy source and density modulate the expression of immunologic stress in chicks. Journal of Nutrition 123, 1714–1723.CrossRefGoogle ScholarPubMed
Besedovsky, H., Rey, A. D., Sorkin, E. & Dinarello, C. A. (1986) Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 233, 652–654.CrossRefGoogle ScholarPubMed
Bories, P. N., Feger, J., Benbernou, N., Rouzeau, J.-D., Agneray, J. & Durand, G. (1990) Prevalence of tri- and tetraantennary glycans of human alpha 1-acid glycoprotein in release of macrophage inhibitor of interleukin-1 activity. Inflammation 14, 315–323.CrossRefGoogle ScholarPubMed
Bradley, S. F. & Kauffman, C. A. (1988) Protein malnutrition and the febrile response in the Fisher rat. Journal of Leukocyte Biology 43, 36–40.CrossRefGoogle Scholar
Bradley, S. F., Kuluger, M. J. & Kauffman, C. A. (1987) Age and protein malnutrition effects on the febrile response. Gerontology 33, 99–108.CrossRefGoogle ScholarPubMed
Chiu, K. M., Mortensen, R. F., Osmond, A. P. & Gewurz, H. (1977) Interactions of alpha 1-acid glycoprotein with the immune system. Immunology 32, 997–1005.Google ScholarPubMed
Coyle, P., Philcox, J. C. & Rofe, A. M. (1993) Corticosterone enhances the zinc and interleukin-6-mediated induction of metallothionein in cultured rat hepatocytes. Journal of Nutrition 123, 1464–1470.CrossRefGoogle ScholarPubMed
Curtis, M. J. & Flack, I. H. (1980) The effect of Escherichia coli endotoxins on the concentration of corticosterone and growth hormone in the plasma of the domestic fowl. Research of Veterinary Science 28, 123–127.CrossRefGoogle ScholarPubMed
Drabik, M. D., Schnure, F. C., Mok, K. T., Moldawer, L. L., Dinarello, C. A., Blackburn, G. L. & Bistrian, B. R. (1987) Effect of protein depletion and short-term parenteral refeeding on the host response to interleukin-1 administration. Journal of Laboratory and Clinical Medicine 109, 509–516.Google ScholarPubMed
Eisenberg, S. P., Evans, R. J., Arend, W. P., Verderber, E., Brewer, M. T., Hannum, C. H. & Thompson, R. C. (1990) Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature 343, 341–346.CrossRefGoogle ScholarPubMed
Fleck, A. (1989) Clinical and nutritional aspects of changes in acute-phase proteins during inflammation. Proceedings of the Nutrition Society 48, 347–354.CrossRefGoogle ScholarPubMed
Flynn, A., Loftus, M. A. & Finke, J. H. (1984) Production of interleukin-1 and interleukin-2 in allogeneic mixed lymphocyte cultures under copper, magnesium and zinc deficient conditions. Nutrition Research 4, 673–679.CrossRefGoogle Scholar
Friedman, H., Newton, C., Widen, R., Klein, T. & Spitzer, J. D. (1992) Continuous endotoxin infusion suppresses rat spleen cell production of cytokines. Proceedings of the Society for Experimental Biology and Medicine 199, 360–364.CrossRefGoogle ScholarPubMed
Grimble, R. F. (1990) Nutrition and cytokine action. Nutrition Research Reviews 3, 193–210.CrossRefGoogle ScholarPubMed
Grimble, R. F. (1992) Dietary manipulation of the inflammatory response. Proceedings of the Nutrition Society 51, 285–294.CrossRefGoogle ScholarPubMed
Guyre, P. M., Girard, M. T., Morganelli, P. M. & Manganiello, P. D. (1988) Glucocorticoid effects on the production and actions of immune cytokines. Journal of Steroid Biochemistry 30, 89–93.CrossRefGoogle ScholarPubMed
Hannum, C. H., Wilcox, C. J., Arend, P. A., Joslin, G., Dripps, D. J., Heimdal, P. L., Armes, L. G., Sommer, A., Eisenberg, S. P. & Thompson, R. C. (1990) Interleukiu-1 receptor antagonist activity of a human interleukin-1 inhibitor. Nature 343, 336–340.CrossRefGoogle ScholarPubMed
Helyar, L. & Sherman, A. R. (1987) Iron deficiency and interleukin-1 production by rat leukocytes. American Journal of Clinical Nutrition 46, 346–352.CrossRefGoogle ScholarPubMed
Hoffman-Goetz, L., Bell, R. C. & Keir, R. (1985) Effect of protein malnutrition and interleukin-l on in vivo rabbit lymphocyte mitogenesis. Nutrition Research 5, 769–780.CrossRefGoogle Scholar
Hoffman-Goetz, L. & Kluger, M. J. (1979) Protein deprivation: its effects on fever and plasma iron during bacterial infection in rabbits. Journal of Physiology 295, 419–430.CrossRefGoogle ScholarPubMed
Hoffman-Goetz, L., McFarlane, D., Bistrian, B. R. & Blackburn, G. L. (1981) Febrile and plasma iron responses of rabbits injected with endogenous pyrogen from malnourished patients. American Journal of Clinical Nutrition 34, 1109–1116.CrossRefGoogle ScholarPubMed
Hoffman-Goetz, L. & Marcon, T. (1983) Effect of in vitro amino acid supplementation on endogenous pyrogen fever. Nutrition Research 3, 237–241.CrossRefGoogle Scholar
Johnson, R. W., Curtis, S. E., Dantzer, R., Bahr, J. M. & Kelley, K. W. (1993) Sickness behavior in birds caused by peripheral or central injection of endotoxin. Physiology and Behavior 53, 343–348.CrossRefGoogle ScholarPubMed
Kauffman, R. A., Jones, P. G. & Kluger, M. J. (1982) Fever and malnutrition: endogenous pyrogen/interleukin-1 in malnourished patients. American Journal of Clinical Nutrition 44, 449–452.CrossRefGoogle Scholar
Keenan, R. A, Modawer, L. L., Yang, R. D., Kawamura, I., Blackburn, G. L. & Bistrian, R. R. (1982) An altered response by peripheral leukocytes to synthesize or release leukocyte endogenous mediator in critically ill protein-malnourished patients. Journal of Laboratory and Clinical Medicine 100, 844–857.Google ScholarPubMed
Klasing, K. C. (1988) Nutritional aspects of leukocytic cytokines. Journal of Nutrition 118, 1436–1446.CrossRefGoogle ScholarPubMed
Klasing, K. C. & Barnes, D. M. (1988) Decreased amino acid requirements of growing chicks due to immunologic stress. Journal of Nutrition 118, 1158–1164.CrossRefGoogle ScholarPubMed
Klasing, K. C. & Johnstone, B. J. (1991) Monokines in growth and development. Poultry Science 70, 1781–1789.CrossRefGoogle ScholarPubMed
Klasing, K. C., Laurin, D. E., Peng, R. K. & Fry, D. M. (1987) Immunologically mediated growth depression in chicks: influence of feed intake, corticosterone and interleukin-1. Journal of Nutrition 117, 1629–1637.CrossRefGoogle ScholarPubMed
Laurin, D. E. & Klasing, K. C. (1987) Effects of repetitive immunogen injections and fasting versus feeding on iron, zinc and copper metabolism in chicks. Biological Trace Element Research 14, 153–165.CrossRefGoogle ScholarPubMed
Makino, T., Saito, M., Horiguchi, S. & Kina, K. (1982) A highly sensitive colorimetric determination of serum zinc using water–soluble pyridylazo dye. Clinica Chimica Acta 120, 127–135.Google ScholarPubMed
Motoi, Y., Itoh, H., Tamura, K., Miyamoto, T., Ohashi, T. & Nagasawa, S. (1992) Correlation of serum concentration of alpha 1-acid glycoprotein with lymphocyte blastogenesis and development of experimentally induced or naturally acquired hepatic abscesses in cattle. American Journal of Veterinary Research 53, 514–579.CrossRefGoogle ScholarPubMed
National Research Council (1984) Nutrient Requirements of poultry, 8th revised ed., pp. 35–47. Washington, DC: National Academic Press.Google Scholar
Powis, G. (1975) Binding of catecholamines to human serum. Biochemical Pharmacology 24, 707–712.CrossRefGoogle ScholarPubMed
Sager, G., Bratlid, H. & Lettle, C. (1987) Binding of catecholamines to alpha-1 acid glycoprotein, albumin and lipoproteins in human serum. Biochemical Pharmacology 36, 3607–3612.CrossRefGoogle ScholarPubMed
Saito, M., Horiguchi, D. & Kina, K. (1981) Spectrophotometric determination of tracers of iron(II)with novel water-soluble nitrosophenolderivatives (in Japanese). Bunseki Kagaku 30, 635–639.CrossRefGoogle Scholar
Takahashi, K., Kaji, N., Akiba, Y. & Tamura, K. (1994) Plasma alpha-1 acid glycoprotein concentration in broilers: influence of age, sex and injection of Escherichia coli lipopolysaccharide. British Poultry Science 35, 507–511.CrossRefGoogle ScholarPubMed
Trechsel, U., Wener, L. & Watson, R. R. (1985) Stimulation of interleukin 1 and 3 production by retinoic acid in vitro. Biochemical Journal 230, 339–344.CrossRefGoogle ScholarPubMed
Wan, J. M. F., Haw, M. P. & Blackburn, G. L. (1989) Nutrition, immune function, and inflammation: an overview. Proceedings of the Nutrition Society 48, 315–335.CrossRefGoogle ScholarPubMed
Winchurch, R. A. (1988) Activation of thymocyte response to Interleukin-1 by zinc. Clinical Immunology and Immunopathology 47, 174–180.CrossRefGoogle ScholarPubMed
Wing, E. J., Stanko, R. T., Winkelstein, A. & Adibi, S. A. (1983) Fasting–enhanced immune effector mechanisms in obese subjects. American Journal of Medicine 75, 91–96.CrossRefGoogle ScholarPubMed