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The estimation of whole-body zinc and Zn turnover in rheumatoid and osteoarthritis using 65Zn tracer

Published online by Cambridge University Press:  09 March 2007

A. C. Kennedy
Affiliation:
Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow G4 0EH and Department of Nuclear Medicine, Royal Infirmary and West of Scotland Health Boards, Department of Clinical Physics and Bio-Engineering, Glasgow
R. G. Bessent
Affiliation:
Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow G4 0EH and Department of Nuclear Medicine, Royal Infirmary and West of Scotland Health Boards, Department of Clinical Physics and Bio-Engineering, Glasgow
P. Davis
Affiliation:
Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow G4 0EH and Department of Nuclear Medicine, Royal Infirmary and West of Scotland Health Boards, Department of Clinical Physics and Bio-Engineering, Glasgow
P. M. G. Reynolds
Affiliation:
Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow G4 0EH and Department of Nuclear Medicine, Royal Infirmary and West of Scotland Health Boards, Department of Clinical Physics and Bio-Engineering, Glasgow
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Abstract

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1. A method of estimating whole-body zinc, and Zn balances using a two-compartment model in combination with whole-body counting of 65Zn, is described. The method is applied to patients with rheumatoid and osteoarthritis.

2. The results suggested that there was not a wide variation in whole-body Zn and Zn turnover in individuals with these two diseases and no clearcut difference between patients with one or the other.

Type
Papers of direct relevance to Clinical and Human Nutrition
Copyright
Copyright © The Nutrition Society 1978

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