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Functional foods and food supplements for athletes: from myths to benefit claims substantiation through the study of selected biomarkers

Published online by Cambridge University Press:  09 March 2007

Fred Brouns ,
Michiel van Nieuwenhoven ,
Asker Jeukendrup  and
Wouter van Marken Lichtenbelt
Fred Brouns*
Affiliation:
Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands Cerestar-Cargill Vilvoorde R&D Centre, Havenstraat 84, B-1800 Vilvoorde, Belgium
Michiel van Nieuwenhoven
Affiliation:
Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
Asker Jeukendrup
Affiliation:
School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Wouter van Marken Lichtenbelt
Affiliation:
Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
*
*Corresponding author: Dr F. Brouns, fax +32 2 2570740, email fbrouns@be.cerestar.com
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Abstract

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The development of the sports food market and industrial involvement have led to numerous nutritional studies to define the type of nutrients that are most suited to support energy metabolism, fluid balance and muscle function. The key question in many of these studies was: ‘Does the product lead to a significant product/consumer benefit that can be used as a claim on the package?’ New methods and techniques have been developed, partly with sponsorship of the food industry, with the goal of measuring the effects of specific nutrients and supplements on athletic performance and metabolism. In line with this development, a wide variety of supplements and sports foods/drinks labelled with various performance or health benefit statements have been launched on the sports nutrition market. Although a variety of products have been tested clinically, there are also many products on the market with benefit claims that cannot be supported by sound nutritional and sports physiological science. The current short review highlights some of the methods and biomarkers that are used to substantiate product/consumer benefit claims for foods and drinks that are marketed as functional foods for athletes.

Keywords

Sports foodEnergy metabolismAthletic performanceBenefit claimsBiomarkers
Type
Research Article
Information
British Journal of Nutrition , Volume 88 , Issue S2 , November 2002 , pp. S177 - S186
Copyright
Copyright © The Nutrition Society 2002

References

Adopo, E, Peronnet, F, Massicotte, D, Brisson, GR & Hillaire-Marcel, C (1994) Respective oxidation of exogenous glucose and fructose given in the same drink during exercise. Journal of Applied Physiology 76, 1014–1019.Google Scholar
Arner, P (1999) Microdialysis use in human exercise studies. Proceedings of the Nutrition Society 58, 913–917.CrossRefGoogle Scholar
Balsom, PD, Soderlund, B & Ekblom, B (1994) Creatine in humans, with special reference to creatine supplementation. Sports Medicine 18, 268–280.Google Scholar
Beckers, E, Leiper, JB & Davidson, J (1992) Comparison of aspiration and scintigraphic techniques for the measurement of gastric emptying rates of liquids in humans. Gut 31, 115–117.Google Scholar
Beckers, E, Rehrer, NJ & Brouns, F (1988) Determination of total gastric volume, gastric secretion and residual meal using the double sampling technique of George. Gut 29, 1725–1729.Google Scholar
Boesch, C, Décombaz, J, Slotboom, J & Kreis, R (1999) Observation of intramyocellular lipids by means of H magnetic resonance spectroscopy. proceedings of the Nutrition Society 58, 841–850.Google Scholar
Boileau, RA & Horswill, CA (2000) Body composition in sports: measurement and applications for weight gain. In Exercise and Sport Science, pp. 319–338 [Garret, WE and Kirkendall, DT, editors]. Philadelphia, PA: Lippincott, Williams & Wilkins.Google Scholar
Brouns, F (1991 a) Etiology of gastrointestinal disturbances during endurance events. Scandinavian Journal of Medicine and Science in Sports 1, 66–77.Google Scholar
Brouns, F (1991 b) Heat-sweat-dehydration-rehydration: a praxis oriented approach. Journal of Sports Science 9, 143–152.Google Scholar
Brouns, F (1997) Aspects of dehydration and rehydration in sport. World Reviews in Nutrition and Diet 82, 63–80.Google Scholar
Brouns, F (2002) Essentials of Sports Nutrition. Chichester: John Wiley & Sons (in press).Google Scholar
Brouns, F & Beckers, E (1993) Is the gut an athletic organ: digestion, absorption and exercise. Sports Medicine 15, 242–257.Google Scholar
Brouns, F & Kovacs, E (1997 a) Functional drinks for athletes. Trends in Food Science and Technology 8, 414–421.Google Scholar
Brouns, F & Kovacs, E (1997 b) Functional foods for athletes. Trends in Food Science and Technology 8, 358–363.CrossRefGoogle Scholar
Brouns, F & van der vusse, G (1998) Utilization of lipids during exercise in human subjects: metabolic and dietary constraints. British Journal of Nutrition 79, 117–128.Google Scholar
Charles, F, Camilleri, M, Phillips, SF, Thomforde, GM & Forstrom, LA (1995) Scintigraphy of the whole gut: clinical evaluation of transit disorders. Mayo Clinical Proceedings 70, 113.CrossRefGoogle ScholarPubMed
Clarckson, PM (1992) Exercise induced muscle damage: animal and human models. Medicine Science Sports Exercise 24, 510–511.Google Scholar
Coggan, AR (1999) Use of stable isotopes to study carbohydrate and fat metabolism at the whole-body level. Proceedings of the Nutrition Society 58, 953–961.CrossRefGoogle ScholarPubMed
Coyle, EF, Coggan, AR, Hemmert, MK & Ivy, JL (1986) Muscle glycogen utilization during prolonged strenuous exercise when fed carbohydrate. Journal of Applied Physiology 61, 165–172.Google Scholar
Dill, DB & Costill, DL (1974) Calculation of percentage changes in volumes of blood, plasma and red cells in dehydration. Journal of Applied Physiology 37, 247–248.Google Scholar
Duthie, GG (1999) Determination of activity of antioxidants in human subjects. Proceedings of the Nutrition Society 58, 1015–1024.CrossRefGoogle ScholarPubMed
Evans, WJ (1991) Muscle damage: nutritional considerations. International Journal of Sports Nutrition 1, 214–224.Google Scholar
Folinsbee, LJ (2000) Effects of air pollutants on exercise. In Exercise and Sport Science, pp. 285–298 [Garret, WE and Kirkendall, DT, editors]. Philadelphia, PA: Lippincott, Williams & Wilkins.Google Scholar
Frayn, KN (1999) Macronutrient metabolism of adipose tissue at rest and during exercise: a methodological viewpoint. Proceedings of the Nutrition Society 58, 877–886.Google Scholar
Gadian, DG (1995) NMR and its Applications to Living Systems. Oxford: Oxford University Press.Google Scholar
Halliwell, B & Gutteridge, JMC (1985) Free Radicals in Biology and Medicine. Oxford: Clarenden Press.Google Scholar
Hawley, JA, Brouns, F & Jeukendrup, A (1998) Strategies to enhance fat utilization during exercise. Sports Medicine 25, 241–257.Google Scholar
Hawley, JA, Dennis, SC & Noakes, TD (1992) Oxidation of carbohydrate ingested during prolonged endurance exercise. Sports Medicine 14, 27–42.Google Scholar
Heerschap, A, Houtman, C, in't Zandt, HJA, Van den bergh, AJ & Wieringa, B (1999) Introduction to in vivo 31P magnetic resonance spectroscopy of (human) skeletal muscle. Proceedings of the Nutrition Society 58, 861–870.CrossRefGoogle ScholarPubMed
Henriksson, J (1999) Microdialysis of skeletal muscle at rest. Proceedings of the Nutrition Society 58, 919–923.CrossRefGoogle ScholarPubMed
Hoppeler, H, Billeter, R, Horvath, PJ, Leddy, JJ & Pendergast, DR (1999) Muscle structure with low and high fat diets in well trained male runners. International Journal of Sports Medicine 20, 522–526.CrossRefGoogle ScholarPubMed
Hultman, E (1967) Studies on muscle metabolism of glycogen and active phosphate in man with special reference to exercise and diet. Scandinavian Journal of Clinical and Laboratory Investigation 19, Suppl. 94, 1–64.Google Scholar
Jackson, MJ (1999) An overview of methods for assessment of free radical activity in biology. Proceedings of the Nutrition Society 58, 1001–1006.CrossRefGoogle ScholarPubMed
Jenkins, RR (1988) Free radical chemistry: relationship to exercise. Sports Medicine 5, 156–170.Google Scholar
Jeukendrup, AE (1999) Dietary fat and physical performance. Current Opinions in Clinical Nutrition and Metabolism Care 2, 521–526.Google Scholar
Jeukendrup, AE, Brouns, F, Wagenmakers, AJM & Saris, WHM (1997) Carbohydrate feedings improve 1 h time trial cycling performance. International Journal of Sports Medicine 18, 125–129.Google Scholar
Jeukendrup, AE & Jentjens, R (2000) Oxidation of carbohydrate feedings during prolonged exercise: current thoughts, guidelines and directions for future research. Sports Medicine 29, 407–424.Google Scholar
Jeukendrup, AE, Saris, WHM, Brouns, F & Kester, ADM (1995) A new validated endurance performance test. Medicine Science Sport Exercise 27, 266–270.Google Scholar
Jeukendrup, AE, Saris, WHM & Wagenmakers, AJM (1998) Fat metabolism during exercise: a review. Part III: The effects of nutritional interventions. International Journal of Sports Medicine 19, 371–379.Google Scholar
Kanter, M (1994) Free radicals, exercise and antioxidant supplementation. International Journal of Sport Nutrition 4, 205–220.Google Scholar
Kearney, JT, Rundell, KW & Wilber, RL (2000) Measurement of work and power in sport. In Exercise and Sport Science, pp. 31–52 [Garret, WE and Kirkendall, DT, editors]. Philadelphia, PA: Lippincott, Williams & Wilkins.Google Scholar
Kleiner, SM, Bazzarre, TL & Litchford, MD (1990) Metabolic profiles, diet, and health practices of championship male and female bodybuilders. Journal of the American Dietetic Association 90, 962–967.Google Scholar
Landau, BR (1999) Glycerol production and utilization measured using stable isotopes. Proceedings of the Nutrition Society 58, 973–978.Google Scholar
Leiper, JB & Maughan, RJ (1988) Experimental models for the investigation of water and solute transport in man: implications for oral rehydration solutions. Drugs 36, Suppl. 4, 65–79.Google Scholar
Lemon, PWR (2000) Protein metabolism during exercise. In Exercise and Sport Science, pp. 19–30 [Garret, WE and Kirkendall, DT, editors]. Philadelphia, PA: Lippincott, Williams & Wilkins.Google Scholar
Levitt, MD (1969) Production and excretion of hydrogen gas in man. New England Journal of Medicine 281, 122–127.Google Scholar
Li, LJ (2000) Free radicals and antioxidants in exercise and sports. In Exercise and Sport Science, pp. 299–317 [WE Garret and DT Kirkendall, editors]. Philadelphia, PA: Lippincott, Williams & Wilkins.Google Scholar
Mcdonald, IA (1999) Arterio-venous differences to study macronutrient metabolism: introduction and overview. Proceedings of the Nutrition Society 58, 871–875.Google Scholar
Mcmurray, RG & Hackney, AC (2000) Endocrine responses to exercise and training. In Exercise and Sport Science, pp. 135–162 [Garret, WE and Kirkendall, DT, editors]. Philadelphia, PA: Lippincott, Williams & Wilkins.Google Scholar
Maughan, R (1999) Nutritional ergogenic aids and exercise performance. Nutrition Research Reviews 12, 255–276.Google Scholar
Maughan, RJ (1986) Exercise induced muscle cramp: a prospective biochemical study in marathon runners. Journal of Sports Science 4, 31–34.CrossRefGoogle ScholarPubMed
Nicholas, CW, Nuttall, FE & Williams, C (2000) The Loughborough Intermittent Shuttle Test: a field test that simulates the activity pattern of soccer. Journal of Sports Science 18, 97–104.Google Scholar
Op, t'EindeB, van leempurtte, B, Brouns, F & van der vusse, G (2001) No effects of oral ribose supplementation on repeated maximal exercise and de novo ATP resynthesis. Journal of Applied Physiology 91, 2278–2281.Google Scholar
Paton, CD & Hopkins, WG (2001) Tests of cycling performance. Sports Medicine 31, 489–496.Google Scholar
Penning, C, Gielkens, HA, Hemelaar, M, Lamers, CB & Masclee, AA (2001) Reproducibility of antroduodenal motility during prolonged ambulatory recording. Neurogastroenterology and Motility 2, 133–141.Google Scholar
Poulsen, HE, Weimann, A & Loft, S (1999) Methods to detect DNA damage by free radicals: relation to exercise. Proceedings of the Nutrition Society 58, 1007–1014.Google Scholar
Powers, SK & Lennon, SL (1999) Analysis of cellular responses to free radicals: focus on exercise and skeletal muscle. Proceedings of the Nutrition Society 58, 1025–1033.Google Scholar
Price, TB, Rothman, DL & Shulman, RG (1999) NMR of glycogen in exercise. Proceedings of the Nutrition Society 58, 851–859.CrossRefGoogle ScholarPubMed
Rennie, MJ (1999) An introduction to the use of tracers in nutrition and metabolism. Proceedings of the Nutrition Society 58, 935–944.Google Scholar
Rennie, MJ & Tipton, KD (2000) Protein and amino acid metabolism during and after exercise and the effects of nutrition. Annual Review of Nutrition 20, 457–483.Google Scholar
Romer, LM, Barrington, JP & Jeukendrup, AE (2001) Effects of oral creatine supplementation on high intensity, intermittent exercise performance in competitive squash players. International Journal of Sports Medicine 22, 546–552.Google ScholarPubMed
Schabort, EJ, Hawley, JA, Hopkins, WG & Blum, H (1999) High reliability of performance of well-trained rowers on a rowing ergometer. Journal of Sports Science 17, 627–632.Google Scholar
Schoeman, MN, Tippett, MD, Akkermans, LMA, Dent, J & Holloway, RH (1995) Mechanisms of gastroesophageal reflux in ambulant healthy human subjects. Gastroenterology 108, 83–91.Google Scholar
Smith, LL & Miles, MP (2000) Exercise induced muscle injury and inflammation. In Exercise and Sport Science, pp. 401–412. [Garret, WE and Kirkendall, DT, editors]. Philadelphia, PA: Lippincott, Williams & Wilkins.Google Scholar
Spriet, L (1999) Ergogenic aids: recent advances and threats. In Optimizing Sports Performance, pp. 185–238 [Lamb, DR and Murray, D, editors]. Carmel, CA: Cooper Publishing.Google Scholar
Van hall, G (1999) Correction factors for 13C-labelled substrate oxidation at whole-body and muscle level. Proceedings of the Nutrition Society 58, 979–986.Google Scholar
Van hall, G, Gonzalez-alonso, J, Sacchetti, M & Saltin, B (1999) Skeletal muscle substrate metabolism during exercise: methodological considerations. Proceedings of the Nutrition Society 58, 899–912.Google Scholar
Van Marken Lichtenbelt, WD (2001) The use of bioelectrical impedance analysis (BIA) for estimation of body composition. In Body Composition Analysis of Animals. A Handbook of Nondestructive Methods, pp. 161–187 [Speakman, J, editor]. Edinburgh: Cambridge University Press.CrossRefGoogle Scholar
Van Marken Lichtenbelt, WD & Fogelmholm, M (1999) Body composition. In Regulation of Food Intake and Energy Expenditure, pp. 383–404 [Westerterp-Plantenga, MS, Steffens, AB and Tremblay, A, editors]. Milan: Medical Publishing & New Media (EDRA).Google Scholar
Van marken lichtenbelt, WD, Kester, A, Baarends, EM & Westerterp, KR (1996) Bromide dilution in adults: optimal equilibration time after oral administration. Journal of Applied Physiology 81, 653–656.Google Scholar
Van nieuwenhoven, MA, Brouns, F & Brummer, RJ (2000) Exercise and gastrointestinal function. In Exercise and Sport Science, pp. 191–216 [Garret, WE and Kirkendall, DT, editors]. Philadelphia, PA: Lippincott, Williams & Wilkins.Google Scholar
Van nieuwenhoven, MA, Wagenmakers, AJM, Senden, JMG, Brouns, F & Brummer, R-JM (1999) Performance of the [13C]-acetate gastric emptying breath test during physical exercise. European Journal of Clinical Investigation 29, 922–928.Google Scholar
Vergauwen, L, Brouns, F & Hespel, P (1998) Carbohydrate supplementation improves stroke performance in tennis. Medicine Science Sports Exercise 30, 1289–1295.Google Scholar
Volek, JS (2000) Enhancing exercise performance: nutritional implications. In Exercise and Sport Science, pp. 471–486 [Garret, WE and Kirkendall, DT, editors]. Philadelphia, PA: Lippincott, Williams & Wilkins.Google Scholar
Volfinger, I, Lassourd, V, Michaux, JM, Braun, JP & Toutain, PL (1994) Kinetic evaluation of muscle damage during exercise by calculation of amounts of creatine kinase released. American Journal of Physiology 266, R434–R441.Google Scholar
Wagenmakers, AJM (1999 a) Nutritional supplements: effects on exercise performance and metabolism. In Perspectives in Exercise Science and Performance, Vol. 12, 207–259 [Lamb, DR, editor]. Carmel, CA: Cooper Publishing.Google Scholar
Wagenmakers, AJM (1999 b) Tracers to investigate protein and amino acid metabolism in human subjects. Proceedings of the Nutrition Society 58, 987–1000.Google Scholar
Walberg-rankin, J, Ecksteien Edmonds, C & Gwazdauskas, FC (1993) Diet and weight changes of female bodybuilders before and after competition. International Journal of Sport Nutrition 3, 87–102.Google Scholar
Wang, Z & Heymsfield, SB et al. (1995) Systematic organisation of body-composition methodology: an overview with emphasis on component-based methods. American Journal of Clinical Nutrition 61, 457–465.CrossRefGoogle ScholarPubMed
Westerterp, KR (1999) Body composition, water turnover and energy turnover assessment with labelled water. Proceedings of the Nutrition Society 58, 945–951.Google Scholar
Westerterp, KR, van marken lichtenbelt, W & Wouters, L (1995) The Maastricht protocol for the measurement of body composition and energy expenditure with labeled water. Obesity Research 49–57.Google Scholar
Williams, MH, Kreider, RB & Branch, JD (1999) Creatine: The Power Supplement. Champaign, IL: Human Kinetics.Google Scholar