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Gestational protein–energy malnutrition affects the composition of developing skins of rat fetuses and their dams

Published online by Cambridge University Press:  09 March 2007

Takashi Miwa ,
Hiromu Shoji ,
Moshe Solomonow ,
Malektaj Yazdani  and
Tetsuo Nakamoto
Takashi Miwa
Affiliation:
Department of Orthopedic Surgery, Louisiana State University Medical Center, 1542 Tulane Avenue, New Orleans, Louisiana 70112, USA
Hiromu Shoji
Affiliation:
Department of Orthopedic Surgery, Louisiana State University Medical Center, 1542 Tulane Avenue, New Orleans, Louisiana 70112, USA
Moshe Solomonow
Affiliation:
Department of Orthopedic Surgery, Louisiana State University Medical Center, 1542 Tulane Avenue, New Orleans, Louisiana 70112, USA
Malektaj Yazdani
Affiliation:
Department of Pediatrics, Louisiana State University Medical Center, 1542 Tulane Avenue, New Orleans, Louisiana 70112, USA
Tetsuo Nakamoto
Affiliation:
Department of Physiology, Louisiana State University Medical Center, 1542 Tulane Avenue, New Orleans, Louisiana 70112, USA
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Abstract

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1. Various biochemical variables of the skins of rat dams and their fetuses in which protein-energy malnutrition was induced during pregnancy were analysed.

2. One group of dams was fed on a 200 g protein/kg diet as a control and the other was fed on a 60 g protein/kg diet as an experimental group. Each group of dams was fed from day 13 of gestation until day 22.

3. Water, protein and hexosamine concentrations of the fetal skins in the malnourished group were greater than those in the control group, whereas in the dams′ skins, protein concentration was greater in the malnourished group than in the control group.

4. Extractability of collagen with neutral salt and pepsin showed no difference between the groups in the skins of fetuses and dams. The content of type III collagen in the fetal skin did not differ between the groups, but was increased in the malnourished dams′ skins compared with that of the control group.

5. The present study showed that protein-energy malnutrition during pregnancy significantly affects the metabolism of the skin in both fetuses and their dams. Furthermore, the skins of fetuses and dams are structurally altered in different ways by this nutritional stress.

Type
Clinical and Human Nutrition papers: Other Studies Relevant to Human Nutrition
Information
British Journal of Nutrition , Volume 58 , Issue 2 , September 1987 , pp. 215 - 220
Copyright
Copyright © The Nutrition Society 1987

References

REFERENCES

Anasuya, A. & Narasinga Rao, B. S. (1970). British Journal of Nutrition 24, 97–107.CrossRefGoogle Scholar
Bailey, A. J. & Robins, S. P. (1972). FEBS Letters 21, 350–354.CrossRefGoogle Scholar
Bornstein, P. & Piez, K. A. (1966). Biochemistry 5, 3460–3473.CrossRefGoogle Scholar
Cabak, V., Dickerson, J. W. T. & Widdowson, E. M. (1963). British Journal of Nutrition 17, 601–616.CrossRefGoogle Scholar
Dawson, R. & Milne, G. (1978). British Journal of Nutrition 39, 181–192.CrossRefGoogle Scholar
Department of Health, Education and Welfare (1972). Ten State Nutrition Survey in the United Stares 1968–1970. DHEW Publication no. (HSM) 72, pp. 8130–8134. Washington, DC: Department of Health, Education and Welfare.Google Scholar
Deyl, Z., Macek, K., Horakova, M. & Adam, M. (1981). Physiologia Bohemoslovaca 30, 243–250.Google Scholar
Epstein, E. H. (1974). Journal of Biological Chemistry 249, 3225–3231.CrossRefGoogle Scholar
Etherington, D. J. & Bailey, A. J. (1982). Collagen Related Research 2, 307–322.CrossRefGoogle Scholar
Gatt, R. & Berman, E. R. (1966). Analytical Biochemistry 15, 167–171.CrossRefGoogle Scholar
Jefferey, J. J., Dipetrillo, T., Counts, D. F. & Catvoneo, K. R. (1985). Collagen Related Research 5, 157–165.CrossRefGoogle Scholar
Klein, L. & Chandrorajan, J. (1977). Proceedings of the National Academy of Sciences, USA 78, 1436–1439.CrossRefGoogle Scholar
Lowry, O. H., Rosebrough, N. J., Farr, A. L. & Randall, R. J. (1951). Journal of Biological Chemistry 193, 267–275.CrossRefGoogle Scholar
Miyahara, T., Murai, A., Tanaka, T., Shiozawa, S. & Kaneyama, M. (1982). Journal of Gerentology 37, 651–655.CrossRefGoogle Scholar
Nakamoto, T., Porter, J. R. & Winkler, M. M. (1983). British Journal of Nutrition 50, 75–80.CrossRefGoogle Scholar
Nowak, T. S. & Munro, H. N. (1977). Nutrition and the Brain, pp. 193–260New York: Raven Press.Google Scholar
Shoji, H., Kimura, H., Miller, D. R. & Nakamoto, T. (1983). Nutrition Research 3, 113–118.CrossRefGoogle Scholar
Spray, C. M. & Widdowson, E. M. (1950). British Journal of Nutrition 4, 332–353.CrossRefGoogle Scholar
Sykes, B., Puddle, B., Francis, M. & Smith, R. (1971). Biochemical and Biophysical Research Communications 43, 340–346.CrossRefGoogle Scholar
Taniguchi, K., Shoji, H., Quinby, G. E. & Nakamoto, T. (1984). Nutrition Research 4, 639–645.CrossRefGoogle Scholar
Woessner, J. F. (1961). Archives of Biochemistry and Biophysics 93, 440–447.CrossRefGoogle Scholar
Zeman, F. J. (1970). Journal of Nutrition 100, 530–538.CrossRefGoogle Scholar
Zlatnik, F. J. & Burmeister, L. F. (1983). American Journal of Obstetrics and Gynecology 146, 199–203.CrossRefGoogle Scholar