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The influence of dietary molybdenum on the xanthine oxidase activity of the milk of ruminants

Published online by Cambridge University Press:  09 March 2007

L. I. Hart
Affiliation:
Hannah Dairy Research Institute, Ayr, Scotland
E. C. Owen
Affiliation:
Hannah Dairy Research Institute, Ayr, Scotland
R. Proudfoot
Affiliation:
Hannah Dairy Research Institute, Ayr, Scotland
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Abstract

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1.The oral administration of sodium molybdate caused a rapid rise of molybdenum in the milk of cows and goats fed on a low-molybdenum diet, but did not affect the xanthine oxidase activities of the milk of either species.

2.In the milks of cows not dosed with sodium molybdate, the regression of the xanthin oxidase activity (y) on the molybdenum content (x) was found to be y = 170.7x+43.86 (r = +0.9386; P < 0.0001), suggesting that all the molybdenum of such milk is bound to enzymically active xanthine oxidase.

3.The molybdenum contents of the milk of goats not does with sodium molybdate varied from animal to anumal and the xanthine oxidase activites were much lower than those of cow' milk. there was no correlation between xanthine oxidase activity and the molybdenum contend of the milks of the goats.

4. These results are discussed in relation to previous work of the authors and others.

Type
Research Article
Copyright
Copyright © The Nutrition Society 1967

References

Andrews, P., Bray, R. C., Edwards, P. & Shooter, K. V. (1964). Biochem. J. 93, 627.CrossRefGoogle Scholar
Avis, P. G., Bergel, F. & Bray, R. C. (1956). J. chem. Soc. p. 1219.CrossRefGoogle Scholar
Bergel, F. & Bray, R. C. (1958). Symp. Biochem. Soc. 15, 64.Google Scholar
Bray, R. C. (1959). Biochem. J. 73, 690.CrossRefGoogle Scholar
Bray, R. C., Pettersson, R. & Ehrenberg, A. (1961). Biochem. J. 81, 178.CrossRefGoogle Scholar
Crossland, A., Owen, E. C. & Proudfoot, R. (1958). Br. J. Nutr. 12, 312.CrossRefGoogle Scholar
De Renzo, E. C., Kaleita, E., Heytler, P. G., Oleson, J. J., Hutchings, B. L. & Williams, J. H. (1953). Archs Biochem. Biophys. 45, 247.CrossRefGoogle Scholar
Fisher, R. A. & Yates, F. (1938). Statistical Tables for Biological, Agricultural and Medical Research. London: Oliver and Boyd.Google Scholar
Green, D. E. & Beinert, H. (1953). Biochim. biophys. Acta 11, 599.CrossRefGoogle Scholar
Hart, L. I. (1964). Some aspects of riboflavin metabolism in the ruminant. PhD Thesis, University of Glasgow.Google Scholar
Keilin, D. & Hartree, E. F. (1945). Biochem. J. 39, 293.CrossRefGoogle Scholar
Kiermeier, F. & Capellari, K. (1958). Biochem. Z. 330, 160.Google Scholar
Litwack, G., Williams, J. N. Jr., Chen, L. & Elvehjem, C. A. (1952). J. Nutr. 47, 299.CrossRefGoogle Scholar
Litwack, G., Williams, J. N. Jr., Fatterpaker, P., Chen, L. & Elvehjem, C. A. (1953). J. Nutr. 49, 579.CrossRefGoogle Scholar
Litwack, G., Williams, J. N. Jr., Feigelson, P. & Elvehjem, C. A. (1950). J. biol. Chem. 187, 605.CrossRefGoogle Scholar
Middleton, G. & Stuckey, R. E. (1954). Analyst, Lond. 79, 138.CrossRefGoogle Scholar
Modi, V. V., Owen, E. C. & Proudfoot, R. (1959). Proc. Nutr. Soc. 18, i.Google Scholar
Morgan, E. J., Stewart, C. P. & Hopkins, F. G. (1922). Proc. R. Soc. B, 94, 109.Google Scholar
Owen, E. C., Hart, L. I. & Hytten, F. E. (1962). Proc. Nutr. Soc. 21, xv.Google Scholar
Richert, D. A. & Westerfeld, W. W. (1953). J. biol. Chem. 203, 915.CrossRefGoogle Scholar
Robert, L. & Polonovski, J. (1955). Disc. Faraday Soc. 20, 54.CrossRefGoogle Scholar
Teresi, J. D., Elvehjem, C. A. & Hart, E. B. (1942). Am. J. Physiol. 137, 504.CrossRefGoogle Scholar
ter Meulen, H. (1932). Nature, Lond. 130, 966.CrossRefGoogle Scholar
Totter, J. R., Burnett, W. T. Jr., Monroe, R. A., Whitney, I. B. & Comar, C. L. (1953). Science, N. Y. 118, 555.CrossRefGoogle Scholar
Underwood, E. J. (1962). Trace Elements in Human and Animal Nutrition, 2nd ed., p. 109. New York and London: Academic Press Inc.Google Scholar
Wieland, H. & Macrae, T. F. (1930). Liebigs Ann. 483, 217.CrossRefGoogle Scholar
Wood, T. B. & Woodman, H. E. (1939). Bull. Minist. Agric. Fish. Fd, Lond. no. 48, 10th ed.Google Scholar
Worden, A. N. (1943). Nature, Lond. 152, 505.CrossRefGoogle Scholar