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A newly constructed and validated isoflavone database for the assessment of total genistein and daidzein intake

Published online by Cambridge University Press:  08 March 2007

Margaret R. Ritchie ,
John H. Cummings ,
Michael S. Morton ,
C. Michael Steel ,
Caroline Bolton-Smith  and
Andrew C. Riches
Margaret R. Ritchie*
Affiliation:
Bute Medical School, University of St Andrews, St Andrews, Fife KY16 9TS, UK
John H. Cummings
Affiliation:
Ninewells Hospita, Division of Neuroscience and Pharmacology, Dundee, UK
Michael S. Morton
Affiliation:
University of Cardiff College of Medicine, Department of Medical Biochemistry, Cardiff, UK
C. Michael Steel
Affiliation:
Bute Medical School, University of St Andrews, St Andrews, Fife KY16 9TS, UK
Caroline Bolton-Smith
Affiliation:
14 Six Mile Bottom Road, West Wratting, Cambridge, UK
Andrew C. Riches
Affiliation:
Bute Medical School, University of St Andrews, St Andrews, Fife KY16 9TS, UK
*
*Corresponding author:fax +44 1334 463482, email mrr3@st-andrews.ac.uk
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Abstract

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The principal phyto-oestrogens (PO) in food are isoflavones, lignans, coumestans and prenylated flavonoids, with isoflavones and lignans being the most commonly found in UK diets. Until recently obtaining accurate data on the PO content of foods was hampered by lack of suitable analytical methods and validation techniques. Furthermore, although PO data exist for some foods, these foods may not be available in the UK. The aim of the present study was to construct a new, comprehensive isoflavone (total genistein + daidzein) database. Using data, mainly from recent GC–MS analysis, for approximately 300 foods available in the UK, and extensive recipe calculations, a new database was constructed containing approximately 6000 foods allocated an isoflavone value. By analysing 7d weighed food diaries, the database was subsequently used to estimate isoflavone intake in two groups of healthy volunteers, omnivores (n 9) and vegetarians (n 10). Mean isoflavone intake in the vegetarian and omnivorous group was 7·4 (sem 3·05) and 1·2 (sem 0·43) mg/d, respectively. Mean intake for the total group was 4·5 (sem 1·89) mg/d. Main food sources of isoflavones for the vegetarian group were soya milk (plain), meat-substitute foods containing textured vegetable protein and soya protein isolate, soya mince, wholemeal bread and rolls, white bread and rolls, croissants and pitta breads, beans, raisins and soya sauce. Main food sources of isoflavones for the omnivorous group were soya yogurts, wholemeal bread and rolls, white bread and rolls, garlic bread, nan bread and brown bread, sultanas and scones.

Keywords

Isoflavone databaseRecipe calculationsDietary intake
Type
Research Article
Information
British Journal of Nutrition , Volume 95 , Issue 1 , January 2006 , pp. 204 - 213
Copyright
Copyright © The Nutrition Society 2006

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