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Prospective comparison of modified-fat–high-carbohydrate with standard low-carbohydrate dietary advice in the treatment of diabetes: one year follow-up study

Published online by Cambridge University Press:  24 July 2007

T. D. R. Hockaday ,
J. M. Hockaday ,
J. I. Mann  and
R. C. Turner
T. D. R. Hockaday
Affiliation:
Diabetic Clinic, Radcliffe Infirmary, Oxford
J. M. Hockaday
Affiliation:
Diabetic Clinic, Radcliffe Infirmary, Oxford
J. I. Mann
Affiliation:
Diabetic Clinic, Radcliffe Infirmary, Oxford
R. C. Turner
Affiliation:
Diabetic Clinic, Radcliffe Infirmary, Oxford
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Abstract

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1. A prospective randomized study of two dietary regimens has been started in newly-diagnosed diabetics to determine their effect on circulating metabolites and on diabetic complications.

2. During the first year of treatment the fasting plasma glucose concentrations on both the low-carbohydrate diet and the high-carbohydrate, modified-fat (MF) diet showed a similar decrease.

3. Plasma cholesterol showed a sustained decrease only in patients recommended a MF diet. Transient changes in plasma triglyceride concentrations occurred in patients on both dietary regimens.

4. Increased plasma cholesterol levels are associated with atheromatous disease which is common in diabetics in Europe and North America. A MF diet may therefore have an advantage in that it lowers the plasma cholesterol as well as being effective in lowering the plasma glucose.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 39 , Issue 2 , March 1978 , pp. 357 - 362
Copyright
Copyright © The Nutrition Society 1978

References

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