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The rat as a model for pigs: comparative values for the digestibility of NSP and other macronutrients

Published online by Cambridge University Press:  09 March 2007

Elisabeth Wisker  and
Knud Erik Bach Knudsen
Elisabeth Wisker
Affiliation:
Christian Albrechts-University of Kiel, Institute of Human Nutrition and Food Science, D-24105 Kiel, Germany
Knud Erik Bach Knudsen*
Affiliation:
Danish Institute of Agricultural Sciences, Department of Animal Nutrition and Physiology, Research Centre Foulum, PO Box 50, DK-8830 Tjele, Denmark
*
*Corresponding author: Research Professor Knud Erik Bach Knudsen, fax +45 89 99 13 78, email KnudErik.Bachknudsen@agrsci.dk
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Abstract

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The present investigation was undertaken to study whether conventional male Wistar rats could be used as a model for pigs with regard to total tract digestibilities of NSP and macronutrients and whether nebacitin-treated rats could be used as a model for small intestinal digestibility in pigs. Nineteen experimental diets prepared from different fractions of wheat and oats, and which all had been evaluated in experiments with ileal cannulated pigs, were used for the present study. There was a close relationship between the total tract digestibilities of organic matter in the two species. The same was the case with regard to the digestibility of total NSP and arabinoxylans, but the values were on average 6 % lower in rats than in pigs. On average, there were no significant differences between rats and pigs with regard to faecal protein digestibility. However, protein in oat-based diets was significantly better digested in the rat than the pig. The digestibility of fat was consistently higher in rats than in pigs, with the biggest difference being found in oat-based diets, in which most of the fat was locked in cell structures. For the wheat-based diets, in which a large proportion of the fat was present as added fat, there was a greater similarity between the two species. In nebacitin-treated rats the digestibility of organic matter, starch, protein and fat was negatively related to the dietary level of NSP, but this model could not be used to predict the small intestinal digestibility of NSP and macronutrients in ileal-cannulated pigs.

Keywords

DigestibilityNon-starch polysaccharidesProteinFatPigsRats
Type
Research Article
Information
British Journal of Nutrition , Volume 90 , Issue 2 , August 2003 , pp. 373 - 383
Copyright
Copyright © The Nutrition Society 2003

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