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Relation of BMI to a dual-energy X-ray absorptiometry measure of fatness

Published online by Cambridge University Press:  09 March 2007

Alfredo Morabia ,
Alan Ross ,
François Curtin ,
Claude Pichard  and
Daniel O. Slosman
Alfredo Morabia*
Affiliation:
Division of Clinical Epidemiology, University Hospital of Geneva, Switzerland
Alan Ross
Affiliation:
Department of Biostatistics, The Johns Hopkins School of Hygiene and Public Health, Baltimore, MD, USA
François Curtin
Affiliation:
Division of Clinical Epidemiology, University Hospital of Geneva, Switzerland
Claude Pichard
Affiliation:
Division of Nutrition, University Hospital of Geneva, Switzerland
Daniel O. Slosman
Affiliation:
Division of Nuclear Medicine, University Hospital of Geneva, Switzerland
*
*Corresponding author: Dr Alfredo Morabia, fax: +41 22 372 9565, email Alfredo.Morabia@hcuge.ch
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Abstract

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Dual-energy X-ray absorptiometry (DXA) is a valid technique for measuring the fat, bone and lean (muscle, organs and water) masses of the body. We evaluated relationships of BMI (kg/m2) with independent measurements of fat and lean masses using DXA in 226 adult volunteers. The evaluation was an application of a general approach to compositional data which has not previously been used for describing body composition. Using traditional regression analyses, when lean mass was held constant, BMI varied with fat mass (men r 0·75, P < 0·05 ; women r 0·85, P < 0·05); when fat mass was held constant, BMI varied with lean mass (men r 0·63, P < 0·05; women r 0·47, P < 0·05). In contrast, a regression model for compositional data revealed that BMI was: (a) strongly associated with log fat mass in both sexes (b1 4·86, P < 0·001 for all women and b1 5·96, P < 0·001 for all men); (b) not associated with bone mass, except in older men; (c) related to lean mass in women but not in men (b3 −4·04, P < 0·001 for all women and b1 −2·59, P < 0·15 for all men). Women with higher BMI tended to have more fat mass and more lean mass than women with lower BMI. Men with higher BMI had more fat mass but similar lean mass to men with lower BMI. Investigators need to be alert to the inaccuracy of BMI to assign a fatness risk factor to individuals, especially among women.

Keywords

Body compositionBMIDual-energy X-ray absorptiometry
Type
Research Article
Information
British Journal of Nutrition , Volume 82 , Issue 1 , July 1999 , pp. 49 - 55
Copyright
Copyright © The Nutrition Society 1999

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