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Response of circulating leptin to Ramadan daytime fasting: a circadian study

Published online by Cambridge University Press:  08 March 2007

André Bogdan ,
Belal Bouchareb  and
Yvan Touitou
André Bogdan
Affiliation:
Laboratoire de Biochimie, Faculté de Médecine Pitié-Salpétrière 91 boulevard de l'hôpital, 75 013, Paris, France
Belal Bouchareb
Affiliation:
Laboratoire d'hormonologie, Hôpital Militaire Universitaire Oran, Algeria
Yvan Touitou*
Affiliation:
Laboratoire de Biochimie, Faculté de Médecine Pitié-Salpétrière 91 boulevard de l'hôpital, 75 013, Paris, France
*
*Corresponding author: Professor Yvan Touitou, fax +3 1 40 77 96 65, email touitou@ccr.jussieu.fr
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Abstract

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Although the effects of short-term fasting on serum leptin concentrations are known, those resulting from long-lasting modifications of food intake schedule, as during the month of Ramadan, have not yet been extensively studied. Therefore, serum concentrations of leptin were measured around the clock at 4-hourly intervals before the beginning of Ramadan and on the twenty-third day of Ramadan daytime fasting in ten male subjects keeping the same usual activity pattern and general synchronisation in both situations. Time series were analysed with repeated measures ANOVA and Cosinor. No significant changes in amplitude or 24 h mean concentration were seen, but significant shifts of 5 h 30 min in peak and trough serum leptin levels were found on the twenty-third day of Ramadan.

Keywords

RhythmsLeptinFastingRamadan
Type
Research Article
Information
British Journal of Nutrition , Volume 93 , Issue 4 , April 2005 , pp. 515 - 518
Copyright
Copyright © The Nutrition Society 2005

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