Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-14T22:26:09.061Z Has data issue: false hasContentIssue false
  • English
  • Français

Retinol transport proteins and concentrations in human amniotic fluid, placenta, and fetal and maternal sera

Published online by Cambridge University Press:  24 July 2007

D. Sklan ,
I. Shalit ,
N. Lasebnik ,
Z. Spirer  and
Y. Weisman
D. Sklan
Affiliation:
Faculty of Agriculture, Israel
I. Shalit
Affiliation:
Departments of Pediatrics, and Obstetrics and Gynaecology, Tel Aviv Medical Center, Tel Aviv University, Sackler Medical School, Tel Aviv, Israel
N. Lasebnik
Affiliation:
Departments of Pediatrics, and Obstetrics and Gynaecology, Tel Aviv Medical Center, Tel Aviv University, Sackler Medical School, Tel Aviv, Israel
Z. Spirer
Affiliation:
Departments of Pediatrics, and Obstetrics and Gynaecology, Tel Aviv Medical Center, Tel Aviv University, Sackler Medical School, Tel Aviv, Israel
Y. Weisman
Affiliation:
Departments of Pediatrics, and Obstetrics and Gynaecology, Tel Aviv Medical Center, Tel Aviv University, Sackler Medical School, Tel Aviv, Israel
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. The proteins binding retinol, and retinol concentrations, were determined in amniotic fluid, placental cytosol and in the fetal and maternal circulation.

2. In non-pregnant women, plasma retinol was almost exclusively found in a transthyretin-retinol-binding-protein complex whereas, in pregnant women, retinol-binding-protein-bound retinol was observed not complexed to transthyretin. This latter fraction increased in concentration with fetal age. These two fractions were the major retinol-protein complexes in amniotic fluid and their relative amounts changed with progress of gestation.

3. In fetal blood both of these fractions were again found, with higher proportions of retinol-binding- protein-bound retinol in the umbilical artery than in the umbilical vein.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 54 , Issue 3 , November 1985 , pp. 577 - 583
Copyright
Copyright © The Nutrition Society 1985

References

Bates, C. J. (1983). Proceedings of the Nutrition Society 42, 65–79.CrossRefGoogle Scholar
Bradford, M. M. (1976). Analytical Biochemistry 72, 248–252.Google Scholar
Burnett, D. & Bradwell, A. R. (1980). Biology of the Neoate 37, 302–307.CrossRefGoogle Scholar
Donoghue, S., Richardson, D. W., Sklan, D. & Kronfeld, D. S. (1982). Journal of Nutrition 112, 2197–2203.Google Scholar
Hemmings, C. & Hemmings, W. A. (1979). In Protein Transmission through living membranes, pp. 269–276 [Hemmings, W. A., editor]. Amsterdam: Elsevier.Google Scholar
Ismadi, S. D. & Olson, J. A. (1975). American Journal of Clinical Nutrition 28, 967–972.CrossRefGoogle Scholar
Ismadi, S. D. & Olson, J. A. (1982). International Journal of Vitamin and Nutrition Research 52, 111–118.Google Scholar
Mallia, A. K., Smith, J. E. & Goodman, D. S. (1975). Journal of Lipid Research 16, 180–188.CrossRefGoogle Scholar
Moore, T. (1971). International Journal of Vitamin and Nutrition Research 41, 301–306.Google Scholar
Nanda, R., May, D. L. & Lite, S. (1977). Oral Biology 22, 613–618.Google Scholar
Ong, D. (1984). Journal of Biological Chemistry 259, 1476–1482.Google Scholar
Parkinson, C. E., Tan, J. C. Y. & Gal, I. (1982). British Journal of Obstetrics and Gynaecology 89, 935–939.Google Scholar
Sklan, D., Blaner, W. S., Adachi, N., Smith, J. E. & Goodman, D. S. (1982). Archives of Biochemistry and Biophysics 214, 35–44.CrossRefGoogle Scholar
Sklan, D. & Donoghue, S. (1982). Biochimica et Biophysica Acta 711, 532–538.Google Scholar
Sklan, D. & Halevy, O. (1984). British Journal of Nutrition 52, 107–114.Google Scholar
Smith, J. E. & Goodman, D. S. (1979). Federation Proceedings 38, 60–65.Google Scholar
Takahashi, Y. I., Smith, J. E. & Goodman, D. S. (1977). American Journal of Physiology 223, E263–E272.Google Scholar
Vahlquist, A., Rask, L., Peterson, P. A. & Berg, T. (1975). Scandinavian Journal of Laboratory and Clinical Investigation 35, 569–575.CrossRefGoogle Scholar
Wallingford, J. C., Milunsky, A. & Underwood, B. A. (1983). American Journal of Clinical Nutrition 38, 377–381.Google Scholar
Wild, A. E. (1974). Symposium of the Society of Experimental Biology 28, 521–546.Google Scholar
Wilson, J. G., Roth, C. B. & Warkany, J. (1953). American Journal of Anatomy 92, 189–217.Google Scholar