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Serum folates in young dairy heifers*

Published online by Cambridge University Press:  09 March 2007

Christiane L. Girard ,
J. Jacques Matte  and
Gabriel L. Roy
Christiane L. Girard
Affiliation:
Agriculture Canada Research Station, Lennoxville, Quebec J1M 1Z3, Canada
J. Jacques Matte
Affiliation:
Agriculture Canada Research Station, Lennoxville, Quebec J1M 1Z3, Canada
Gabriel L. Roy
Affiliation:
Agriculture Canada Research Station, Lennoxville, Quebec J1M 1Z3, Canada
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Abstract

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1. In the first trial, hourly blood samples were drawn during the light period (06·30–20·30 hours) from thirtyfour dairy heifers in two groups of different ages.

2. Concentrations of serum folates were 8·2 (se 0·1) ng/ml at the age of 18·2 (se 0·6) d and 14·8 (se 0·2) ng/ml at 120·7 (se 2·9) d (P ≤ 0·001).

3. In the second trial, forty heifers were randomly assigned to a factorial experiment where age (2 weeks v. 4 months) and quantity of pteroylmonoglutamic acid injected intramuscularly (2·5, 5·0, 10·0 and 20·0 mg) were the two factors studied. Blood samples were taken immediately before injection and on days 1,2,3,4,7 and 10 after the injection.

4. Serum folates reached a maximum on day 1 after the injection of pteroylmonoglutamic acid. The response to the injection was different for the two age groups (P ≤ 0·0002); concentration of serum folates for 2-week-old heifers markedly increased, while in 4-month-old heifers the effect of a supplement of pteroylmonoglutamic acid was less marked.

5. These results might indicate a need for pteroylmonoglutamic acid in young animals during the development of rumen function.

Type
Vitamins
Information
British Journal of Nutrition , Volume 61 , Issue 3 , May 1989 , pp. 595 - 600
Copyright
Copyright © The Nutrition Society 1989

References

Agricultural Research Council (1980). The Nutrient Requirements of Ruminant Livestock. Slough: Commonwealth Agricultural Bureaux.Google Scholar
Arbeiter, K. & Winding, W. (1973). Folatbestimmungen im Serum von Rindern mit besonderem Bezug auf die Fruchtbarkeit. Wiener Tierarzliche Monatsschrift 60, 323–326.Google Scholar
Cox, D. F. (1980). Design and analysis in nutritional and physiological experimentation. Journal of Dairy Science 63, 313–321.CrossRefGoogle ScholarPubMed
Fernandes-Costa, F. & Metz, J. (1979). Role of serum folate binders in the delivery of folate to tissues and to the fetus. British Journal of Haematology 41, 335–342.CrossRefGoogle ScholarPubMed
Gill, J. L. (1978). Design and Analysis of Experiments in the Animal and Medical Sciences Vol. 1. Ames, Iowa: Iowa University Press.Google Scholar
Gill, J. L. & Hafs, H. D. (1971). Analysis of repeated measurements of animals. Journal of Animal Science 33, 331–336.CrossRefGoogle ScholarPubMed
Kon, S. K. & Porter, J. W. G. (1954). The intestinal synthesis of vitamins in ruminants. Vitamins and Hormones 12, 53–68.CrossRefGoogle Scholar
LeClercg, E. L., Leonard, H. W. & Clark, A. G. (1966). Field Plot Technique. Minneapolis, MN: Burgess Publishing Co.Google Scholar
Lorin, D. (1980). Proceedings of the Second International Symposium of Veterinary Laboratory DiagnosticiansLucerne Vol. 2, pp. 153–166.Google Scholar
Mantzos, J. D., Alevizoo-Terzaki, V. & Gyftaki, E. (1974). Folate binding in animal plasma. Acta Haematologica 51, 204–210.CrossRefGoogle ScholarPubMed
Markkanen, T., Pajula, R.-L., Himanen, P. & Virtanen, S. (1974). Binding of folic acid to serum proteins, IV. In some animals species. International Journal for Vitamin and Nutrition Research 44, 347–356.Google ScholarPubMed
Markkanen, T., Pajula, R.-L., Virtanen, S. & Himanen, P. (1972). New carrier protein(s) of folic acid in human serum. Acta Haematologica 48, 145–150.CrossRefGoogle ScholarPubMed
Mornet, P. & Espinasse, J. (1977). Le Veau. Paris: Maloine S. A..Google Scholar
National Research Council (1978). Nutrient Requirements of Domestic Animals. no. 3, Nutrient Requirements of Dairy Cattle 5th revised ed. Washington, DC: National Academy of Sciences.Google Scholar
Roy, J. H. B. (1980). The Calf 4th ed. London: Butterworths.Google Scholar
SAS (1985). User's Guide. Cary, NC: Statistical Analysis System Institute Inc.Google Scholar
Snedecor, G. W. & Cochran, W. G. (1971). Méthodes Statistiques 6th ed. Paris: Association de Coordination Technique Agricole.Google Scholar
Wagner, C. (1985). Folate-binding proteins. Nutrition Reviews 43, 293–299.Google ScholarPubMed
Waxman, S. (1975). Folate binding proteins. British Journal of Haematology 29, 23–29.CrossRefGoogle ScholarPubMed