Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-10T11:40:28.347Z Has data issue: false hasContentIssue false
  • English
  • Français

Mechanisms of insecticide resistance in Aedes aegypti (L.) (Diptera: Culicidae) from Puerto Rico

Published online by Cambridge University Press:  10 July 2009

J. Hemingway ,
R. G. Boddington ,
J. Harris  and
S. J. Dunbar
J. Hemingway*
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, Gower Street, London, WCIE 7HT, UK
R. G. Boddington
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, Gower Street, London, WCIE 7HT, UK
J. Harris
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, Gower Street, London, WCIE 7HT, UK
S. J. Dunbar
Affiliation:
I.C.I., Jealott's Hill Research Station, Bracknell, Berks, RG12 6EY, UK
*
*To whom all correspondence should be sent.
Get access Rights & Permissions [Opens in a new window]

Abstract

A strain of Aedes aegypti (L.) was collected in Rio Piedras, Puerto Rico, in 1987 and reared through to the F2 generation. The strain was shown to be heterozygous for resistance to a range of pyrethroids, but there was no evidence of organophosphate and carbamate resistance. Biochemical studies indicated that the pyrethroid resistance was not metabolically based. Electrophysiological studies at the neuromuscular junction of resistant insects indicated that a kdr (nerve insensitivity) type mechanism was operating in this strain. It is not known whether this mechanism was selected by earlier DDT exposure or by the recent ultra-low-volume applications of pyrethroids.

Type
Original Articles
Information
Bulletin of Entomological Research , Volume 79 , Issue 1 , March 1989 , pp. 123 - 130
Copyright
Copyright © Cambridge University Press 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Booth, J. E., Boyland, E. & Sim, R. (1961). An enzyme from rat liver catalysing conjugation with glutathione.—Biochem. J. 79, 516.Google Scholar
Brown, A. W. A. & Pal, R. (1971). Insecticide resistance in arthropods.—2nd edn, 491 pp. Geneva, Wld Hlth Org. (Monograph ser. no. 38).Google Scholar
Chadwick, P. R., Invest, J. F. & Bowron, M. J. (1977). An example of cross-resistance to pyrethroids in DDT-resistant Aedes aegypti.—Pestic. Sci. 8, 618–624.Google Scholar
Farnham, A. W. (1977). Genetics of resistance of houseflies (Musca domestica L.) to pyrethroids. I. Knock-down resistance.—Pestic. Sci. 8, 631–636.Google Scholar
Hemingway, J., Jayawardena, K. G. I. & Herath, P. R. J. (1986 a). Pesticide resistance mechanisms produced by field selection pressures on Anopheles nigerrimus and A. culicifacies in Sri Lanka.—Bull. Wld Hlth Org. 64, 753–758.Google Scholar
Hemingway, J., Smith, C., Jayawardena, K. G. I. & Herath, P. R. J. (1986 b). Field and laboratory detection of the altered acetylcholinesterase resistance genes which confer organophosphate and carbamate resistance in mosquitoes (Diptera: Culicidae).—Bull. ent. Res. 76, 559–565.Google Scholar
Kulkarni, A. P. & Hodgson, E. (1976). Spectral interactions of insecticide synergists with microsomal cytochrome P-450 from insecticide-resistant and susceptible house flies.—Pestic. Biochem. & Physiol. 6, 183–191.Google Scholar
Lowry, O. H., Rosebrough, N. J., Farr, A. L. & Randall, R. J. (1951). Protein measurement with the folin phenol reagent.—J. biol. Chem. 193, 265.Google Scholar
Malcolm, C. A. & Wood, R. J. (1982). Location of a gene conferring resistance to knockdown by permethrin and bioresmethrin in adults of the BKPM3 strain of Aedes aegypti.—Genetica 59, 233–237.Google Scholar
McDonald, A. E. & Wood, R. J. (1979). Mechanism of DDT resistance in larvae of the mosquito Aedes aegypti L.; the effect of DDT selection.—Pestic. Sci. 10, 383–388.Google Scholar
Rathor, H. R. & Wood, R. J. (1981). In-vivo and in-vitro studies on DDT uptake and metabolism in susceptible and resistant strains of the mosquito Aedes aegypti L.—Pestic. Sci. 12, 255–264.Google Scholar
Rongsriyam, Y. & Busvine, J. R. (1975). Cross-resistance in DDT-resistant strains of various mosquitoes (Diptera, Culicidae).—Bull. ent. Res. 65, 459–471.Google Scholar
Salgado, V. L., Irving, S. N. & Miller, T. A. (1983). Depolarization of motor nerve terminals by pyrethroids in susceptible and kdr-resistant house flies.—Pestic. Biochem. & Physiol. 20, 100–114.Google Scholar
Sawicki, R. M. (1985). Resistance to pyrethroid insecticides in arthropods.—pp. 143–192in Hutson, D. H. & Roberts, T. R. (Eds.). Insecticides.—London, Wiley.Google Scholar