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Clinical Manifestations of Parkinson's Disease and Parkinsonism

Published online by Cambridge University Press:  02 December 2014

Doug Everett Hobson
Doug Everett Hobson*
Affiliation:
University of Manitoba, Department of Medicine, Winnipeg, MB, Canada
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Abstract

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The most common disorder in a patient presenting to a movement disorder clinic will be parkinsonism. The challenge is to provide the patient with the most accurate diagnosis and prognosis possible. The assumption at the time of initial presentation of the clinical diagnosis of Parkinson's disease is often wrong (20-25%). Waiting to see the pattern of progression, and response to medication provides invaluable additional information. This manuscript summarizes the clinical manifestations of Parkinson's disease and the main akinetic-rigid syndromes (progressive supranuclear palsy, multiple system atrophy, cortical-basal ganglionic degeneration, and dementia with Lewy bodies) that make up the differential diagnosis.

Résumé

RÉSUMÉ

La majorité des patients d’une clinique des troubles du mouvement prénte du parkinsonisme. Le dé est de poser le diagnostic et de dérminer le pronostic avec le plus de présion possible. La prémption d’un diagnostic clinique de maladie de Parkinson au moment de la consultation initiale est souvent erroné(20 à5% des cas). Des informations suppléntaires préeuses peuvent éner de l’élution de la maladie et de la rénse àa mécation. Cet article prénte un sommaire des manifestations cliniques de la maladie de Parkinson et des principaux syndromes akineto-rigides (paralysie supranuclére progressive, atrophie multisystéque, dénéscence cortico-basale et dénce à corps de Lewy) faisant partie du diagnostic difféntiel.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 30 , supplement S1: A Peer-Reviewed Supplement to the Canadian Journal of Neurological Sciences , February 2003 , pp. S2 - S9
Copyright
Copyright © The Canadian Journal of Neurological 2003

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